PangenomeCOLN315NCTC8325NewmanUSA300_FPR3757JSNZ04-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

⊟Summary

• organism: Staphylococcus aureus USA300_FPR3757
• locus tag: SAUSA300_RS01835 [old locus tag: SAUSA300_0346 ]
• pan locus tag^?: SAUPAN001884000
• symbol: SAUSA300_RS01835
• pan gene symbol^?: fepC
• synonym:
• product: iron permease FTR1 family protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SAUSA300_RS01835 [old locus tag: SAUSA300_0346 ]
• symbol: SAUSA300_RS01835
• product: iron permease FTR1 family protein
• replicon: chromosome
• strand: +
• coordinates: 398115..399797
• length: 1683
• essential: unknown other strains

⊟Accession numbers

• Location: NC_007793 (398115..399797) NCBI
• BioCyc: SAUSA300_RS01835 BioCyc
• MicrobesOnline: see SAUSA300_0346

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  901
  961
  1021
  1081
  1141
  1201
  1261
  1321
  1381
  1441
  1501
  1561
  1621
  1681
  
  ATGCTAATAACTGCTGCTATGGTGTGTAGCTTTGGGTTACTGAAAAGTCAGGCAGCAGAA
  CAACAAAGTATTAGTGATGTATATAGTGTGATAACGGATGCGAAATCTGCACTTTCTAAT
  AATTCGATATCGAATGACAATAAGCAGAAAGCAATTGAGCAAGTGGTAAGTGCAGTTAAG
  AAATTATCGCTTGAAGATAATAGTGAAAGTAATGCTGTCAAATCAGATGTGAGAAAGCTT
  GAAGATGCAAAAGCGAATGATAATCAAAAAGATACACTTTCGCAATTAACGAAGTCATTA
  ATTGCTTATGAAGAGAAATTGGCTAGTAAAGATGCGGGTTCTAAAATTAAACTATTGCAA
  CAGCAAGTCGATGCTAAAGATGCTGCGATGACAAAAGCGATTAAAGATAAAAATAAAGCG
  GAATTAGAATCTTTGAACAATAGTTTGAATCAGATTTGGACAAGTAATGAAACAGTGATT
  CGCAATTATGACGCAAATCAATATGGACAAATTGAAGTCGCATTATTACAACTTAGAATT
  GCAATTCATAAGTCACCATTAGATACGGCAAAAGTGTCACATGCTTGGACAACTTTTAAA
  TCAAATATTGATCATGTCGATAAAAAAAGTAATACGTCTGCAAATGATCAATACCATGTA
  TCACAATTAAATGATGCGTTAGAGAAGGCGATTAAAGCTATCGACGACAATCAATTGTCG
  GATGCTGATGCTGCGCTTACACATTTTATAGAAACTTGGCCGTATGTTGAAGGTCAAATT
  CAAACTAAAGACGGTGCTTTGTATACGAAAATTGAAGATAAAATACCATATTATCAAAGT
  GTATTAGACGAACATAATAAAGCACATGTGAAAGATGGTTTAGTAGATTTAAATAACCAA
  ATTAAAGAGGTTGTTGGCCATAGTTATAGCTTCGTCGATGTGATGATTATCTTTTTACGT
  GAAGGGCTAGAAGTGTTGTTAATTGTAATGACATTGACTACCATGACGCGTAATGTAAAA
  GATAAGAAAGGGACTGCAAGTGTGATTGGTGGTGCAATTGCCGGACTTGTACTGAGTATT
  ATCTTAGCAATTACGTTTGTAGAAACTTTAGGGAATAGTGGCATTCTTCGTGAAAGTATG
  GAAGCGGGATTAGGTATCGTTGCGGTCATATTAATGTTTATCGTTGGTGTTTGGATGCAC
  AAACGTTCAAATGCAAAACGTTGGAATGACATGATTAAAAATATGTATGCTAATGCGATT
  AGTAATGGTAATTTGGTATTGTTAGCGACGATTGGTTTAATATCTGTGTTGCGTGAAGGT
  GTCGAGGTTATCATTTTCTATATGGGGATGATAGGTGAGCTAGCGACCAAAGATTTTATT
  ATTGGTATTGCTTTAGCTATCGTTATTTTAATCATCTTTGCATTATTATTTAGATTTATA
  GTTAAATTAATACCTATTTTCTATATATTTAGAGTGTTGTCGATCTTTATTTTTATTATG
  GGATTCAAAATGCTTGGCGTAAGTATTCAAAAGTTACAATTATTAGGTGCGATGCCAAGA
  CATGTTATTGAAGGATTCCCAACGATTAACTGGTTGGGCTTTTATCCAAGTTATGAACCA
  TTGATAGCACAAGGTGCTTATATTATGGTAGTTGCTATCTTAATCTTTAAATTTAAAAAA
  TAA
  60
  120
  180
  240
  300
  360
  420
  480
  540
  600
  660
  720
  780
  840
  900
  960
  1020
  1080
  1140
  1200
  1260
  1320
  1380
  1440
  1500
  1560
  1620
  1680
  1683
  

⊟Protein

⊟General

• locus tag: SAUSA300_RS01835 [old locus tag: SAUSA300_0346 ]
• symbol: SAUSA300_RS01835
• description: iron permease FTR1 family protein
• length: 560
• theoretical pI: 7.82963
• theoretical MW: 62087.9
• GRAVY: 0.1775

⊟Function

• TIGRFAM:
  Unknown function General FTR1 family protein (TIGR00145; HMM-score: 89.8)
• TheSEED: see SAUSA300_0346
• PFAM:
  LysE (CL0292) FTR1; Iron permease FTR1 family (PF03239; HMM-score: 48.2)
  and 4 more
  no clan defined DUF6677; Family of unknown function (DUF6677) (PF20382; HMM-score: 12.1)
  STATB_N; Signal transducer and activator of transcription b N-terminal (PF24629; HMM-score: 11.8)
  DUF6350; Family of unknown function (DUF6350) (PF19877; HMM-score: 11.6)
  RecG_N; RecG N-terminal helical domain (PF17190; HMM-score: 9.1)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic Membrane
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 10
  • Cellwall Score: 0
  • Extracellular Score: 0
  • Internal Helices: 6
• DeepLocPro: Cytoplasmic Membrane
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 0.9985
  • Cell wall & surface Score: 0
  • Extracellular Score: 0.0015
• LocateP:
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.466602
  • TAT(Tat/SPI): 0.005883
  • LIPO(Sec/SPII): 0.030313
• predicted transmembrane helices (TMHMM): 6

⊟Accession numbers

• GI: see SAUSA300_0346
• RefSeq: WP_002869272 NCBI
• UniProt: see SAUSA300_0346

⊟Protein sequence

• MLITAAMVCSFGLLKSQAAEQQSISDVYSVITDAKSALSNNSISNDNKQKAIEQVVSAVKKLSLEDNSESNAVKSDVRKLEDAKANDNQKDTLSQLTKSLIAYEEKLASKDAGSKIKLLQQQVDAKDAAMTKAIKDKNKAELESLNNSLNQIWTSNETVIRNYDANQYGQIEVALLQLRIAIHKSPLDTAKVSHAWTTFKSNIDHVDKKSNTSANDQYHVSQLNDALEKAIKAIDDNQLSDADAALTHFIETWPYVEGQIQTKDGALYTKIEDKIPYYQSVLDEHNKAHVKDGLVDLNNQIKEVVGHSYSFVDVMIIFLREGLEVLLIVMTLTTMTRNVKDKKGTASVIGGAIAGLVLSIILAITFVETLGNSGILRESMEAGLGIVAVILMFIVGVWMHKRSNAKRWNDMIKNMYANAISNGNLVLLATIGLISVLREGVEVIIFYMGMIGELATKDFIIGIALAIVILIIFALLFRFIVKLIPIFYIFRVLSIFIFIMGFKMLGVSIQKLQLLGAMPRHVIEGFPTINWLGFYPSYEPLIAQGAYIMVVAILIFKFKK

⊟Experimental data

• experimentally validated:
• protein localization: data available for COL
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator: Fur* see SAUSA300_0346

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You can add further information about the gene and protein here. [edit]

⊟Literature

⊟References

⊟Relevant publications