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⊟Summary[edit | edit source]
- pan ID?: SAUPAN005061000
- symbol?: —
- synonym:
- description?: phage head-tail adapter protein
- phage head-tail adapter protein
- phage head-tail adaptor
- phage protein
- phage head-tail joining protein
descriptions from strain specific annotations:
- strand?: -
- coordinates?: 5228101..5228463
- synteny block?: BlockID0039340
- occurrence?: in 44% of 34 strains
htcp (cp) : serogroup F prophage head-tail closure-connection protein [1]
Most staphylococcal prophage require four small proteins to connect phage capsids to phage tails. Head-tail closure-connection protein (HTCP) binds to HTAP conformation-adapted capsids forming a cap to prevent premature genome leakage and a capsid capable of binding phage tails. During the head-tail connection process, HTCP will form the capsid-tail interface with the joining protein component of the phage tail assembly.
⊟Orthologs[edit | edit source]
04-02981:
SA2981_1922
08BA02176:
—
11819-97:
—
6850:
—
71193:
ST398NM01_2926
ECT-R 2:
ECTR2_1834
ED133:
—
ED98:
—
HO 5096 0412:
SAEMRSA15_18760
JH1:
SaurJH1_2053
JH9:
SaurJH9_2017
JKD6008:
SAA6008_02016
JKD6159:
—
LGA251:
—
M013:
—
MRSA252:
SAR2058
MSHR1132:
—
MSSA476:
—
Mu3:
SAHV_1946
Mu50:
SAV1960
MW2:
—
RF122:
—
ST398:
—
T0131:
SAT0131_02095
TCH60:
—
TW20:
SATW20_19530
USA300_TCH1516:
USA300HOU_1965
VC40:
—
⊟Genome Viewer[edit | edit source]
| N315 | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
N315 MKKVFKKPRITTKRLNTRVHFYKYTENNGPEAGEKEEKLLYSCWASIDGVWLRELEQAIS
USA300_FPR3757 MKKVFKKPRITTKRLNTRVHFYKYTENNGPEAGEKEEKLLYSCWASIDGVWLRELEQAIS
************************************************************
N315 NGTQNDIKLYIRDPQGDYLPSEEHYLEIESRYFKNRLNIKQVSPDLDNKDFIMIRGGYSS
USA300_FPR3757 NGTQNDIKLYIRDPQGDYLPSEEHYLEIESRYFKNRLNIKQVSPDLDNKDFIMIRGGYSS
************************************************************
- ↑ R Lurz, E V Orlova, D Günther, P Dube, A Dröge, F Weise, M van Heel, P Tavares
Structural organisation of the head-to-tail interface of a bacterial virus.
J Mol Biol: 2001, 310(5);1027-37
[PubMed:11501993] [WorldCat.org] [DOI] (P p)Lia Cardarelli, Robert Lam, Ashleigh Tuite, Lindsay A Baker, Paul D Sadowski, Devon R Radford, John L Rubinstein, Kevin P Battaile, Nickolay Chirgadze, Karen L Maxwell, Alan R Davidson
The crystal structure of bacteriophage HK97 gp6: defining a large family of head-tail connector proteins.
J Mol Biol: 2010, 395(4);754-68
[PubMed:19895817] [WorldCat.org] [DOI] (I p)Paulo Tavares, Sophie Zinn-Justin, Elena V Orlova
Genome gating in tailed bacteriophage capsids.
Adv Exp Med Biol: 2012, 726;585-600
[PubMed:22297531] [WorldCat.org] [DOI] (P p)