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⊟Summary[edit | edit source]
- pan ID?: SAUPAN005055000
- symbol?: —
- synonym:
- description?: phage tail protein
- phage tail protein
- phage major tail protein
- phi77 ORF020-like protein, phage major tail protein
- Phi13 family phage major tail protein
- Phage_hypothetical protein
- phage major tail protein, phi13 family protein
- prophage pi2 protein 39
- pseudogene
descriptions from strain specific annotations:
- strand?: -
- coordinates?: 5219932..5222395
- synteny block?: BlockID0039310
- occurrence?: in 53% of 34 strains
mtpS : serogroup F prophage major tail tube protein small subunit [1]
Most staphylococcal prophages require two major tail tube proteins to form orderly coiled polymers around the tail tape measure protein. After nucleation at the distal baseplate, MtpS monomers polymerize, spiraling their way up the tail tape measure protein, displacing tail assembly chaperones and incorporating MtpL monomers as necessary to maintain proper tight spirals. Upon reaching the end of the tape measure protein, the final MtpS spiral is stabilized by a ring of tail-completion/"neck" proteins resulting in a tail tube that is structurally-secure and competent for binding to phage capsids.
⊟Orthologs[edit | edit source]
04-02981:
SA2981_1919
08BA02176:
—
11819-97:
—
6850:
RSAU_000604
71193:
ST398NM01_2923
ECT-R 2:
ECTR2_1831
ED133:
—
ED98:
—
HO 5096 0412:
SAEMRSA15_18730
JH1:
SaurJH1_2050
JH9:
SaurJH9_2014
JKD6008:
SAA6008_02013
JKD6159:
—
JSNZ:
—
LGA251:
—
M013:
—
MRSA252:
SAR2054
MSHR1132:
—
MSSA476:
—
Mu3:
SAHV_1943
Mu50:
SAV1957
MW2:
—
RF122:
—
ST398:
—
T0131:
SAT0131_02092
TCH60:
HMPREF0772_11182
TW20:
SATW20_19500
USA300_TCH1516:
USA300HOU_1962
VC40:
—
⊟Genome Viewer[edit | edit source]
| N315 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
N315 MAVKHASAPKAYINITGLGFAKLTKEGAELKYSDITKTRGLQKIGVETGGELKTAYADGG
Newman MAVKHASAPKAYINITGLGFAKLTKEGAELKYSDITKTRGLQKIGVETGGDLKTAYADGG
USA300_FPR3757 MVVKQASAPKAYFNITGLGFAKLTKEGAKLEYSDITKTRGLQKIGVETGGDLKTAYADGG
*.**:*******:***************:*:*******************:*********
N315 PIESGNTDGEGKISLQMHAFPKEIRKIVFNEDYDEDGVYEEKQGKQNNYVAVWFRQERRD
Newman PIESGNTDGEGKISLQMHAFPKEIRKIVFNEEYDEDGVYKETQGKQNNYVAIWFRQERRD
USA300_FPR3757 PIESGNTDGEGKISLQMHAFPKEIRKIVFNEEYDEYGVYKETQGKQNNYVAIWFRQERRD
*******************************:*** ***:*.*********:********
N315 GTFRTVLLPKVMFTNPKIDGETAEKDWDFSSEEVEGEALFPLVDNKKSVRKYIFDSANMT
Newman GTFRTVLLPKVMFTNPKIDGETAEKDWDFSSEEVEGEALFPLVDNKKSVRKYIFDSANMT
USA300_FPR3757 GTFRTVLLPKVMFTNPKIDGETAEKDWDFSSEEVEGEALFPLIDNKKSVRKYIFDSANMT
******************************************:*****************
N315 NHDGDGEKGEEAFLKKILGEEYTGNVTEGNEETL
Newman NHDGDGEKGEEAFLKKILGEEYTGNVTEGNEETL
USA300_FPR3757 NHSGNGEKGEEAFLKKILGEEYTGNVTEDNGETL
**.*:***********************.* ***
- ↑ Jun Xu, Roger W Hendrix, Robert L Duda
Conserved translational frameshift in dsDNA bacteriophage tail assembly genes.
Mol Cell: 2004, 16(1);11-21
[PubMed:15469818] [WorldCat.org] [DOI] (P p)Isabelle Auzat, Anja Dröge, Frank Weise, Rudi Lurz, Paulo Tavares
Origin and function of the two major tail proteins of bacteriophage SPP1.
Mol Microbiol: 2008, 70(3);557-69
[PubMed:18786146] [WorldCat.org] [DOI] (I p)