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⊟Summary[edit | edit source]
- pan ID?: SAUPAN004564000
- symbol?: splC
- synonym:
- description?: serine protease SplC
- serine protease SplC
- serine protease
- peptidase S1 and S6, chymotrypsin/Hap
- peptidase S1 and S6 chymotrypsin/Hap
- S1B family serine protease SplC
- serine proteinase
descriptions from strain specific annotations:
- strand?: -
- coordinates?: 4796516..4801433
- synteny block?: BlockID0035530
- occurrence?: in 76% of 34 strains
splC : staphylococcal serine protease SplC [1]
• A crystal structure is available : 2AS9
⊟Orthologs[edit | edit source]
04-02981:
SA2981_1766 (splC)
08BA02176:
—
11819-97:
MS7_1812 (splC)
6850:
RSAU_001668 (splC)
71193:
—
ECT-R 2:
ECTR2_1643
ED133:
SAOV_1796 (splC)
ED98:
SAAV_1819 (splC)
HO 5096 0412:
—
JH1:
SaurJH1_1897
JH9:
SaurJH9_1862
JKD6008:
—
JKD6159:
—
LGA251:
SARLGA251_16950 (splC)
M013:
—
MRSA252:
SAR1906 (splC)
MSHR1132:
—
MSSA476:
SAS1734
Mu3:
SAHV_1796 (splC)
Mu50:
SAV1811 (splC)
MW2:
MW1753 (splC)
RF122:
SAB1671c (splC)
ST398:
—
T0131:
SAT0131_01930
TCH60:
HMPREF0772_11330 (splC)
TW20:
SATW20_18090 (splC)
USA300_TCH1516:
USA300HOU_1804 (splC)
VC40:
SAVC_08295
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 | |
| JSNZ |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MNKNIVIKSMAALAILTSVTGINAAVVEETQQIANAEKNVTQVKDTNIFPYNGVVSFKDA
N315 MNKNIVIKSMAALAILTSVTGINAAVVEETQQIANAEKNVTQVKDTNNFPYNGVVSFKDA
NCTC8325 MNKNIVIKSMAALAILTSVTGINAAVVEETQQIANAEKNVTQVKDTNIFPYNGVVSFKDA
Newman MNKNIVIKSMAALAILTSVTGINAAVVEETQQIANAEKNVTQVKDTNIFPYNGVVSFKDA
USA300_FPR3757 MNKNIVIKSMAALAILTSVTGINAAVVEETQQIANAEKNVTQVKDTNIFPYNGVVSFKDA
*********************************************** ************
COL TGFVIGKNTIITNKHVSKDYKVGDRITAHPNGDKGNGGIYKIKSISDYPGDEDISVMNIE
N315 TGFVIGKNTIITNKHVSKDYKVGDRITAHPNGDKGNGGIYKIKSISDYPGDEDISVMNIE
NCTC8325 TGFVIGKNTIITNKHVSKDYKVGDRITAHPNGDKGNGGIYKIKSISDYPGDEDISVMNIE
Newman TGFVIGKNTIITNKHVSKDYKVGDRITAHPNGDKGNGGIYKIKSISDYPGDEDISVMNIE
USA300_FPR3757 TGFVIGKNTIITNKHVSKDYKVGDRITAHPNGDKGNGGIYKIKSISDYPGDEDISVMNIE
************************************************************
COL EQAVERGPKGFNFNENVQAFNFAKDAKVDDKIKVIGYPLPAQNSFKQFESTGTIKRIKDN
N315 EQAVERGPKGFNFNENVQAFNFAKDAKVDDKIKVIGYPLPAQNSFKQFESTGTIKRIKDN
NCTC8325 EQAVERGPKGFNFNENVQAFNFAKDAKVDDKIKVIGYPLPAQNSFKQFESTGTIKRIKDN
Newman EQAVERGPKGFNFNENVQAFNFAKDAKVDDKIKVIGYPLPAQNSFKQFESTGTIKRIKDN
USA300_FPR3757 EQAVERGPKGFNFNENVQAFNFAKDAKVDDKIKVIGYPLPAQNSFKQFESTGTIKRIKDN
************************************************************
COL ILNFDAYIEPGNSGSPVLNSNNEVIGVVYGGIGKIGSEYNGAVYFTPQIKDFIQKHIEQ
N315 ILNFDAYIEPGNSGSPVLNSNNEVIGVVYGGIGKIGSEYNGAVYFTPQIKDFIQKHIEQ
NCTC8325 ILNFDAYIEPGNSGSPVLNSNNEVIGVVYGGIGKIGSEYNGAVYFTPQIKDFIQKHIEQ
Newman ILNFDAYIEPGNSGSPVLNSNNEVIGVVYGGIGKIGSEYNGAVYFTPQIKDFIQKHIEQ
USA300_FPR3757 ILNFDAYIEPGNSGSPVLNSNNEVIGVVYGGIGKIGSEYNGAVYFTPQIKDFIQKHIEQ
***********************************************************
- ↑ Grzegorz M Popowicz, Grzegorz Dubin, Justyna Stec-Niemczyk, Anna Czarny, Adam Dubin, Jan Potempa, Tad A Holak
Functional and structural characterization of Spl proteases from Staphylococcus aureus.
J Mol Biol: 2006, 358(1);270-9
[PubMed:16516230] [WorldCat.org] [DOI] (P p)