⊟Summary[edit | edit source]

pan ID^?: SAUPAN004134000
symbol^?: sodA
synonym:
description^?: superoxide dismutase
- superoxide dismutase
- Fe/Mn family superoxide dismutase
- superoxide dismutase, Mn, putative
- superoxide dismutase Mn/Fe family protein
- superoxide dismutase SodA
- Superoxide dismutase [Mn] 1
- Manganese superoxide dismutase
- Superoxide dismutase (Fe)
- superoxide dismutase, Mn
- superoxide dismutase [Mn] (General stress protein 24)(GSP24)
strand^?: -
coordinates^?: 4402806..4403405
synteny block^?: BlockID0031640
occurrence^?: in 100% of 34 strains

sodA : endogenous ROS-inducible superoxide dismutase ^[1]

• A crystal structure is available: 6EX3

⊟Orthologs[edit | edit source]

COL:

SACOL1610 (sodA2)

N315:

SA1382 (sodA)

NCTC8325:

SAOUHSC_01653

Newman:

NWMN_1456 (sodA)

USA300_FPR3757:

SAUSA300_1513

04-02981:

SA2981_1511 (sodA)

08BA02176:

C248_1596 (sodA)

11819-97:

MS7_1570 (sodA)

6850:

RSAU_001418 (sodA2)

71193:

ST398NM01_1618

ECT-R 2:

ECTR2_1403

ED133:

SAOV_1553

ED98:

SAAV_1545 (sodA2)

HO 5096 0412:

SAEMRSA15_14730 (sodA)

JH1:

SaurJH1_1645

JH9:

SaurJH9_1611

JKD6008:

SAA6008_01522 (sodA)

JKD6159:

SAA6159_01488 (sodA)

JSNZ:

JSNZ_001544

LGA251:

SARLGA251_14590 (sodA)

M013:

M013TW_1568

MRSA252:

SAR1630 (sodA)

MSHR1132:

SAMSHR1132_13930

MSSA476:

SAS1491

Mu3:

SAHV_1540 (sodA)

Mu50:

SAV1553 (sodA)

MW2:

MW1505 (sodA)

RF122:

SAB1425c (sodA)

ST398:

SAPIG1618

T0131:

SAT0131_01647 (purR)

TCH60:

HMPREF0772_11587 (sodA2)

TW20:

SATW20_15490 (sodA)

USA300_TCH1516:

USA300HOU_1555 (sodA)

VC40:

SAVC_07015

⊟Genome Viewer[edit | edit source]

⊟Alignments[edit | edit source]

alignment of orthologues:
CLUSTAL format alignment by MAFFT L-INS-i (v7.307)

COL             MAFELPKLPYAFDALEPHFDKETMEIHHDRHHNTYVTKLNAAVEGTDLESKSIEEIVANL
N315            MAFELPKLPYAFDALEPHFDKETMEIHHDRHHNTYVTKLNAAVEGTDLESKSIEEIVANL
NCTC8325        MAFELPKLPYAFDALEPHFDKETMEIHHDRHHNTYVTKLNAAVEGTDLESKSIEEIVANL
Newman          MAFELPKLPYAFDALEPHFDKETMEIHHDRHHNTYVTKLNAAVEGTDLESKSIEEIVANL
USA300_FPR3757  MAFELPKLPYAFDALEPHFDKETMEIHHDRHHNTYVTKLNAAVEGTDLESKSIEEIVANL
                ************************************************************

COL             DSVPANIQTAVRNNGGGHLNHSLFWELLSPNSEEKGTVVEKIKEQWGSLEEFKKEFADKA
N315            DSVPANIQTAVRNNGGGHLNHSLFWELLSPNSEEKGTVVEKIKEQWGSLEEFKKEFADKA
NCTC8325        DSVPANIQTAVRNNGGGHLNHSLFWELLSPNSEEKGTVVEKIKEQWGSLEEFKKEFADKA
Newman          DSVPANIQTAVRNNGGGHLNHSLFWELLSPNSEEKGTVVEKIKEQWGSLEEFKKEFADKA
USA300_FPR3757  DSVPANIQTAVRNNGGGHLNHSLFWELLSPNSEEKGTVVEKIKEQWGSLEEFKKEFADKA
                ************************************************************

COL             AARFGSGWAWLVVNNGQLEIVTTPNQDNPLTEGKTPILGLDVWEHAYYLKYQNKRPDYIG
N315            AARFGSGWAWLVVNNGQLEIVTTPNQDNPLTEGKTPILGLDVWEHAYYLKYQNKRPDYIG
NCTC8325        AARFGSGWAWLVVNNGQLEIVTTPNQDNPLTEGKTPILGLDVWEHAYYLKYQNKRPDYIG
Newman          AARFGSGWAWLVVNNGQLEIVTTPNQDNPLTEGKTPILGLDVWEHAYYLKYQNKRPDYIG
USA300_FPR3757  AARFGSGWAWLVVNNGQLEIVTTPNQDNPLTEGKTPILGLDVWEHAYYLKYQNKRPDYIG
                ************************************************************

COL             AFWNVVNWEKVDELYNATK
N315            AFWNVVNWEKVDELYNATK
NCTC8325        AFWNVVNWEKVDELYNATK
Newman          AFWNVVNWEKVDELYNATK
USA300_FPR3757  AFWNVVNWEKVDELYNATK
                *******************

↑ M O Clements, S P Watson, S J Foster
Characterization of the major superoxide dismutase of Staphylococcus aureus and its role in starvation survival, stress resistance, and pathogenicity.
J Bacteriol: 1999, 181(13);3898-903
[PubMed:10383955] [WorldCat.org] [DOI] (P p)M W Valderas, M E Hart
Identification and characterization of a second superoxide dismutase gene (sodM) from Staphylococcus aureus.
J Bacteriol: 2001, 183(11);3399-407
[PubMed:11344148] [WorldCat.org] [DOI] (P p)Michail H Karavolos, Malcolm J Horsburgh, Eileen Ingham, Simon J Foster
Role and regulation of the superoxide dismutases of Staphylococcus aureus.
Microbiology (Reading): 2003, 149(Pt 10);2749-2758
[PubMed:14523108] [WorldCat.org] [DOI] (P p)Janina Treffon, Diego Chaves-Moreno, Silke Niemann, Dietmar Helmut Pieper, Thomas Vogl, Johannes Roth, Barbara C Kahl
Importance of superoxide dismutases A and M for protection of Staphylococcus aureus in the oxidative stressful environment of cystic fibrosis airways.
Cell Microbiol: 2020, 22(5);e13158
[PubMed:31895486] [WorldCat.org] [DOI] (I p)

[1] M O Clements, S P Watson, S J Foster
Characterization of the major superoxide dismutase of Staphylococcus aureus and its role in starvation survival, stress resistance, and pathogenicity.
J Bacteriol: 1999, 181(13);3898-903
[PubMed:10383955] [WorldCat.org] [DOI] (P p)M W Valderas, M E Hart
Identification and characterization of a second superoxide dismutase gene (sodM) from Staphylococcus aureus.
J Bacteriol: 2001, 183(11);3399-407
[PubMed:11344148] [WorldCat.org] [DOI] (P p)Michail H Karavolos, Malcolm J Horsburgh, Eileen Ingham, Simon J Foster
Role and regulation of the superoxide dismutases of Staphylococcus aureus.
Microbiology (Reading): 2003, 149(Pt 10);2749-2758
[PubMed:14523108] [WorldCat.org] [DOI] (P p)Janina Treffon, Diego Chaves-Moreno, Silke Niemann, Dietmar Helmut Pieper, Thomas Vogl, Johannes Roth, Barbara C Kahl
Importance of superoxide dismutases A and M for protection of Staphylococcus aureus in the oxidative stressful environment of cystic fibrosis airways.
Cell Microbiol: 2020, 22(5);e13158
[PubMed:31895486] [WorldCat.org] [DOI] (I p)

[1]

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Contents

⊟Summary[edit | edit source]

⊟Orthologs[edit | edit source]

⊟Genome Viewer[edit | edit source]

⊟Alignments[edit | edit source]

COL
N315
NCTC8325
Newman
USA300_FPR3757

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⊟Summary[edit | edit source]

⊟Orthologs[edit | edit source]

⊟Genome Viewer[edit | edit source]

⊟Alignments[edit | edit source]