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⊟Summary[edit | edit source]
- pan ID?: SAUPAN003548000
- symbol?: topA
- synonym:
- description?: DNA topoisomerase I
- DNA topoisomerase I
- type I DNA topoisomerase
- DNA topoisomerase TopA
descriptions from strain specific annotations:
- strand?: +
- coordinates?: 3882965..3885040
- synteny block?: BlockID0026250
- occurrence?: in 100% of 33 strains
⊟Orthologs[edit | edit source]
04-02981:
SA2981_1208 (topA)
08BA02176:
C248_1281 (topA)
11819-97:
MS7_1208 (topA)
6850:
RSAU_001132 (topA)
71193:
ST398NM01_1252
ECT-R 2:
ECTR2_1106 (topA)
ED133:
SAOV_1252 (topA)
ED98:
SAAV_1224 (topA)
HO 5096 0412:
SAEMRSA15_10830 (topA)
JH1:
SaurJH1_1335
JH9:
SaurJH9_1310
JKD6008:
SAA6008_01205 (topA)
JKD6159:
SAA6159_01105 (topA)
LGA251:
SARLGA251_11610 (topA)
M013:
M013TW_1190
MRSA252:
SAR1226 (topA)
MSHR1132:
SAMSHR1132_10930
MSSA476:
SAS1184
Mu3:
SAHV_1240
Mu50:
SAV1250
MW2:
MW1133
RF122:
SAB1112 (topA)
ST398:
SAPIG1252 (topA)
T0131:
SAT0131_01301
TCH60:
HMPREF0772_11980 (topA)
TW20:
SATW20_12440 (topA)
USA300_TCH1516:
USA300HOU_1181 (topA)
VC40:
SAVC_05415
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL --MADNLVIVESPAKAKTIEKYLGKKYKVIASMGHVRDLPRSQMGVDTEDNYEPKYITIR
N315 --MADNLVIVESPAKAKTIEKYLGKKYKVIASMGHVRDLPRSQMGVDTEDNYEPKYITIR
NCTC8325 MTLADNLVIVESPAKAKTIEKYLGKKYKVIASMGHVRDLPRSQMGVDTEDNYEPKYITIR
Newman MTLADNLVIVESPAKAKTIEKYLGKKYKVIASMGHVRDLPRSQMGVDTEDNYEPKYITIR
USA300_FPR3757 MTLADNLVIVESPAKAKTIEKYLGKKYKVIASMGHVRDLPRSQMGVDTEDNYEPKYITIR
:*********************************************************
COL GKGPVVKELKKHAKKAKNVFLASDPDREGEAIAWHLSKILELEDSKENRVVFNEITKDAV
N315 GKGPVVKELKKHAKKAKNVFLASDPDREGEAIAWHLSKILELEDSKENRVVFNEITKDAV
NCTC8325 GKGPVVKELKKHAKKAKNVFLASDPDREGEAIAWHLSKILELEDSKENRVVFNEITKDAV
Newman GKGPVVKELKKHAKKAKNVFLASDPDREGEAIAWHLSKILELEDSKENRVVFNEITKDAV
USA300_FPR3757 GKGPVVKELKKHAKKAKNVFLASDPDREGEAIAWHLSKILELEDSKENRVVFNEITKDAV
************************************************************
COL KESFKNPREIEMNLVDAQQARRILDRLVGYNISPVLWKKVKKGLSAGRVQSVALRLVIDR
N315 KESFKNPREIEMNLVDAQQARRILDRLVGYNISPVLWKKVKKGLSAGRVQSVALRLVIDR
NCTC8325 KESFKNPREIEMNLVDAQQARRILDRLVGYNISPVLWKKVKKGLSAGRVQSVALRLVIDR
Newman KESFKNPREIEMNLVDAQQARRILDRLVGYNISPVLWKKVKKGLSAGRVQSVALRLVIDR
USA300_FPR3757 KESFKNPREIEMNLVDAQQARRILDRLVGYNISPVLWKKVKKGLSAGRVQSVALRLVIDR
************************************************************
COL ENEIRNFKPEEYWTIEGEFRYKKSKFNAKFLHYKNKPFKLKTKKDVEKITAALDGDQFEI
N315 ENEIRNFKPEEYWTIEGEFRYKKSKFNAKFLHYKNKPFKLKTKKDVEKITAALDGDQFEI
NCTC8325 ENEIRNFKPEEYWTIEGEFRYKKSKFNAKFLHYKNKPFKLKTKKDVEKITAALDGDQFEI
Newman ENEIRNFKPEEYWTIEGEFRYKKSKFNAKFLHYKNKPFKLKTKKDVEKITAALDGDQFEI
USA300_FPR3757 ENEIRNFKPEEYWTIEGEFRYKKSKFNAKFLHYKNKPFKLKTKKDVEKITAALDGDQFEI
************************************************************
COL TNVTKKEKTRNPANPFTTSTLQQEAARKLNFKARKTMMVAQQLYEGIDLKKQGTIGLITY
N315 TNVTKKEKTRNPANPFTTSTLQQEAARKLNFKARKTMMVAQQLYEGIDLKKQGTIGLITY
NCTC8325 TNVTKKEKTRNPANPFTTSTLQQEAARKLNFKARKTMMVAQQLYEGIDLKKQGTIGLITY
Newman TNVTKKEKTRNPANPFTTSTLQQEAARKLNFKARKTMMVAQQLYEGIDLKKQGTIGLITY
USA300_FPR3757 TNVTKKEKTRNPANPFTTSTLQQEAARKLNFKARKTMMVAQQLYEGIDLKKQGTIGLITY
************************************************************
COL MRTDSTRISDTAKVEAKQYITDKYGESYTSKRKASGKQGDQDAHEAIRPSSTMRTPDDMK
N315 MRTDSTRISDTAKAEAKQYITDKYGESYTSKRKASGKQGDQDAHEAIRPSSTMRTPDDMK
NCTC8325 MRTDSTRISDTAKVEAKQYITDKYGESYTSKRKASGKQGDQDAHEAIRPSSTMRTPDDMK
Newman MRTDSTRISDTAKVEAKQYITDKYGESYTSKRKASGKQGDQDAHEAIRPSSTMRTPDDMK
USA300_FPR3757 MRTDSTRISDTAKVEAKQYITDKYGESYTSKRKASGKQGDQDAHEAIRPSSTMRTPDDMK
*************.**********************************************
COL SFLTKDQYRLYKLIWERFVASQMAPAILDTVSLDITQGDIKFRANGQTIKFKGFMTLYVE
N315 SFLTKDQYRLYKLIWERFVASQMAPAILDTVSLDITQGDIKFRANGQTIKFKGFMTLYVE
NCTC8325 SFLTKDQYRLYKLIWERFVASQMAPAILDTVSLDITQGDIKFRANGQTIKFKGFMTLYVE
Newman SFLTKDQYRLYKLIWERFVASQMAPAILDTVSLDITQGDIKFRANGQTIKFKGFMTLYVE
USA300_FPR3757 SFLTKDQYRLYKLIWERFVASQMAPAILDTVSLDITQGDIKFRANGQTIKFKGFMTLYVE
************************************************************
COL TKDDSDSEKENKLPKLEQGDKVTATQIEPAQHYTQPPPRYTEARLVKTLEELKIGRPSTY
N315 TKDDSDSEKENKLPKLEQGDKVTATQIEPAQHYTQPPPRYTEARLVKTLEELKIGRPSTY
NCTC8325 TKDDSDSEKENKLPKLEQGDKVTATQIEPAQHYTQPPPRYTEARLVKTLEELKIGRPSTY
Newman TKDDSDSEKENKLPKLEQGDKVTATQIEPAQHYTQPPPRYTEARLVKTLEELKIGRPSTY
USA300_FPR3757 TKDDSDSEKENKLPKLEQGDKVTATQIEPAQHYTQPPPRYTEARLVKTLEELKIGRPSTY
************************************************************
COL APTIDTIQKRNYVKLESKRFVPTELGEIVHEQVKEYFPEIIDVEFTVNMETLLDKIAEGD
N315 APTIDTIQKRNYVKLESKRFVPTELGEIVHEQVKEYFPEIIDVEFTVNMETLLDKIAEGD
NCTC8325 APTIDTIQKRNYVKLESKRFVPTELGEIVHEQVKEYFPEIIDVEFTVNMETLLDKIAEGD
Newman APTIDTIQKRNYVKLESKRFVPTELGEIVHEQVKEYFPEIIDVEFTVNMETLLDKIAEGD
USA300_FPR3757 APTIDTIQKRNYVKLESKRFVPTELGEIVHEQVKEYFPEIIDVEFTVNMETLLDKIAEGD
************************************************************
COL ITWRKVIDGFFSSFKQDVERAEEEMEKIEIKDEPAGEDCEICGSPMVIKMGRYGKFMACS
N315 ITWRKVIDGFFSSFKQDVERAEEEMEKIEIKDEPAGEDCEVCGSPMVIKMGRYGKFMACS
NCTC8325 ITWRKVIDGFFSSFKQDVERAEEEMEKIEIKDEPAGEDCEICGSPMVIKMGRYGKFMACS
Newman ITWRKVIDGFFSSFKQDVERAEEEMEKIEIKDEPAGEDCEICGSPMVIKMGRYGKFMACS
USA300_FPR3757 ITWRKVIDGFFSSFKQDVERAEEEMEKIEIKDEPAGEDCEICGSPMVIKMGRYGKFMACS
****************************************:*******************
COL NFPDCRNTKAIVKSIGVKCPKCNDGDVVERKSKKNRVFYGCSKYPECDFISWDKPIGRDC
N315 NFPDCRNTKAIVKSIGVKCPKCNDGDVVERKSKKNRVFYGCSKYPECDFISWDKPIGRDC
NCTC8325 NFPDCRNTKAIVKSIGVKCPKCNDGDVVERKSKKNRVFYGCSKYPECDFISWDKPIGRDC
Newman NFPDCRNTKAIVKSIGVKCPKCNDGDVVERKSKKNRVFYGCSKYPECDFISWDKPIGRDC
USA300_FPR3757 NFPDCRNTKAIVKSIGVKCPKCNDGDVVERKSKKNRVFYGCSKYPECDFISWDKPIGRDC
************************************************************
COL PKCNQYLVENKKGKTTQVICSNCDYKEAAQK
N315 PKCNQYLVENKKGKTTQVICSNCDYKEAAQK
NCTC8325 PKCNQYLVENKKGKTTQVICSNCDYKEAAQK
Newman PKCNQYLVENKKGKTTQVICSNCDYKEAAQK
USA300_FPR3757 PKCNQYLVENKKGKTTQVICSNCDYKEAAQK
*******************************