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⊟Summary[edit | edit source]
- pan ID?: SAUPAN003500000
- symbol?: sun
- synonym:
- description?: 16S rRNA (cytosine(967)-C(5))-methyltransferase
- 16S rRNA (cytosine(967)-C(5))-methyltransferase
- 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB
- ribosomal RNA small subunit methyltransferase B
- sun protein
- 16S rRNA m(5)C 967 methyltransferase
- 16S rRNA methyltransferase B
- RNA-binding protein
- RNA-binding Sun protein
- rRNA (cytosine-5-)-methyltransferase
- SA1060 protein
descriptions from strain specific annotations:
- strand?: +
- coordinates?: 3839410..3840795
- synteny block?: BlockID0025790
- occurrence?: in 100% of 34 strains
rsmB (rsmF, sun) : ribosome small subunit methyltransferase B [1]
Ribosome small subunit methyltransferase B (alt: ribosome small subunit nucleobase methyltransferase B, 16S rRNA cytosine (976)-C(5)-methyltransferase) attaches a methyl group to the cytosine nucleobase at the 5-position of residue 976 in 16S ribosomal RNA (S. aureus numbering; cytoisine 967 by E. coli numbering).
- 16S rRNA : C (976) → m5C (967)
⊟Orthologs[edit | edit source]
04-02981:
SA2981_1175
08BA02176:
C248_1247
11819-97:
MS7_1175 (sun)
6850:
RSAU_001099 (sun)
71193:
ST398NM01_1216
ECT-R 2:
ECTR2_1073 (sun)
ED133:
SAOV_1220
ED98:
SAAV_1189 (sun)
HO 5096 0412:
SAEMRSA15_10500
JH1:
SaurJH1_1301
JH9:
SaurJH9_1276
JKD6008:
SAA6008_01172 (sun)
JKD6159:
SAA6159_01070 (sun)
JSNZ:
JSNZ_001186 (rsmB)
LGA251:
SARLGA251_11280 (rsmB)
M013:
M013TW_1155
MRSA252:
SAR1193
MSHR1132:
SAMSHR1132_10580
MSSA476:
SAS1151
Mu3:
SAHV_1207
Mu50:
SAV1217
MW2:
MW1100
RF122:
SAB1081 (sun)
ST398:
SAPIG1216 (sun)
T0131:
SAT0131_01266 (modB)
TCH60:
HMPREF0772_12015 (rsmB)
TW20:
SATW20_12110 (rsmB)
USA300_TCH1516:
USA300HOU_1154
VC40:
SAVC_05250
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL --------------------------MIENVRSLAFDTIQDILNEGAYSNLRINEVLSEN
N315 MSWEKENVSCQLFKWCAKHTSREETYMIENVRSLAFDTIQDILNEGAYSNLRINEVLSEN
NCTC8325 --------------------------MIENVRSLAFDTIQDILNEGAYSNLRINEVLSEN
Newman --------------------------MIENVRSLAFDTIQDILNEGAYSNLRINEVLSEN
USA300_FPR3757 --------------------------MIENVRSLAFDTIQDILNEGAYSNLRINEVLSEN
**********************************
COL ELNAMDKALFTEIVYGTVKRKYTLDFYLKPFVKTKIKAWVRQLLWMSIYQYVYLDKVPNH
N315 ELNAMDKALFTEIVYGTVKRKYTLDFYLKPFVKTKIKAWVRQLLWMSIYQYVYLDKVPNH
NCTC8325 ELNAMDKALFTEIVYGTVKRKYTLDFYLKPFVKTKIKAWVRQLLWMSIYQYVYLDKVPNH
Newman ELNAMDKALFTEIVYGTVKRKYTLDFYLKPFVKTKIKAWVRQLLWMSIYQYVYLDKVPNH
USA300_FPR3757 ELNAMDKALFTEIVYGTVKRKYTLDFYLKPFVKTKIKAWVRQLLWMSIYQYVYLDKVPNH
************************************************************
COL AIINEAVEIAKERGGYHNGNVVNGILRTMMRSDLPDFNEIADPKKRMAIEYSMPKWIIDH
N315 AIINEAVEIAKERGGYHNGNVVNGILRTMMRSDLPDFNEIADPKKRMAIEYSMPKWIIDH
NCTC8325 AIINEAVEIAKERGGYHNGNVVNGILRTMMRSDLPDFNEIADPKKRMAIEYSMPKWIIDH
Newman AIINEAVEIAKERGGYHNGNVVNGILRTMMRSDLPDFNEIADPKKRMAIEYSMPKWIIDH
USA300_FPR3757 AIINEAVEIAKERGGYHNGNVVNGILRTMMRSDLPDFNEIADPKKRMAIEYSMPKWIIDH
************************************************************
COL WATHYGLEETETILQSFLETTSTTVRANLTRASLDDIIEKLQDEGYDVEKDHDLPYCLHI
N315 WATHYGLEETETILQSFLETTSTTVRANLTRASLDDIIEKLQDEGYDVEKDHDLPYCLHI
NCTC8325 WATHYGLEETEKILQSFLETTSTTVRANLTRASLDDIIEKLQDEGYDVEKDHDLPYCLHI
Newman WATHYGLEETETILQSFLETTSTTVRANLTRASLDDIIEKLQDEGYDVEKDHDLPYCLHI
USA300_FPR3757 WATHYGLEETETILQSFLETTSTTVRANLTRASLDDIIEKLQDEGYDVEKDHDLPYCLHI
***********.************************************************
COL GGQPIIHSRSFKDGFVSIQDKSSMFVAHIMNVDRHDHVLDACSAPGGKACHIAEVLMPEG
N315 GGQPIIHSRSFKDGFVSIQDKSSMFVAHIMNVDRHDHVLDACSAPGGKACHIAEVLMPEG
NCTC8325 GGQPIIHSRSFKDGFVSIQDKSSMFVAHIMNVDRHDHVLDACSAPGGKACHIAEVLMPEG
Newman GGQPIIHSRSFKDGFVSIQDKSSMFVAHIMNVDRHDHVLDACSAPGGKACHIAEVLMPEG
USA300_FPR3757 GGQPIIHSRSFKDGFVSIQDKSSMFVAHIMNVDRHDHVLDACSAPGGKACHIAEVLMPEG
************************************************************
COL QVDASDIHDHKIDLINFNIKKLRLTNIKAFQHDATKPYDKTYDKILVDAPCSGLGVMRHK
N315 QVDASDIHDHKIDLINFNIKKLRLTNIKAFQHDATKPYDKTYDKILVDAPCSGLGVMRHK
NCTC8325 QVDASDIHDHKIDLINFNIKKLRLTNIKAFQHDATKPYDKTYDKILVDAPCSGLGVMRHK
Newman QVDASDIHDHKIDLINFNIKKLRLTNIKAFQHDATKPYDKTYDKILVDAPCSGLGVMRHK
USA300_FPR3757 QVDASDIHDHKIDLINFNIKKLRLTNIKAFQYDATKPYDKTYDKILVDAPCSGLGVMRHK
*******************************:****************************
COL PEIKYTQSKQHIESLVELQLEILENVKNNVKIGGEIIYSTCTIEQLENENVIYTFLKNNK
N315 PEIKYTQSKQHIESLVELQLEILENVKNNVKIGGEIIYSTCTIEQLENENVIYTFLKNNK
NCTC8325 PEIKYTQSKQHIESLVELQLEILENVKNNVKIGGEIIYSTCTIEQLENENVIYTFLKNNK
Newman PEIKYTQSKQHIESLVELQLEILENVKNNVKIGGEIIYSTCTIEQLENENVIYTFLKNNK
USA300_FPR3757 PEIKYTQSKQHIESLVELQLEILENVKNNVKIGGEIIYSTCTIEQLENENVIYTFLKNNK
************************************************************
COL NFEFEPFQHPITGELVKTLQIMPQDFNSDGFFITKIKRKDN
N315 NFEFEPFQHPITGELVKTLQIMPQDFNSDGFFITKIKRKDN
NCTC8325 NFEFEPFQHPITGELVKTLQIMPQDFNSDGFFITKIKRKDN
Newman NFEFEPFQHPITGELVKTLQIMPQDFNSDGFFITKIKRKDN
USA300_FPR3757 NFEFEPFQHPITGELVKTLQIMPQDFNSDGFFITKIKRKDN
*****************************************
- ↑ Geoffrey S Briggs, Wiep Klaas Smits, Panos Soultanas
Chromosomal replication initiation machinery of low-G+C-content Firmicutes.
J Bacteriol: 2012, 194(19);5162-70
[PubMed:22797751] [WorldCat.org] [DOI] (I p)Alexander Golubev, Bulat Fatkhullin, Iskander Khusainov, Lasse Jenner, Azat Gabdulkhakov, Shamil Validov, Gulnara Yusupova, Marat Yusupov, Konstantin Usachev
Cryo-EM structure of the ribosome functional complex of the human pathogen Staphylococcus aureus at 3.2 Å resolution.
FEBS Lett: 2020, 594(21);3551-3567
[PubMed:32852796] [WorldCat.org] [DOI] (I p)Adrián González-López, Daniel S D Larsson, Ravi Kiran Koripella, Brett N Cain, Martin Garcia Chavez, Paul J Hergenrother, Suparna Sanyal, Maria Selmer
Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane.
Sci Rep: 2024, 14(1);14253
[PubMed:38902339] [WorldCat.org] [DOI] (I e)