PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

⊟Summary

• pan ID^?: SAUPAN003276000
• symbol^?: folD
• synonym:
• description^?: bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase

  descriptions from strain specific annotations:

  • bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase
  • bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase
  • bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase, FolD
  • bifunctional methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase
  • bifunctional methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate
  • bifunctional protein FolD
  • methylenetetrahydrofolate dehydrogenase
  • Methylenetetrahydrofolate dehydrogenase (NADP+) / Methenyltetrahydrofolate cyclohydrolase
  • tetrahydrofolate dehydrogenase/cyclohydrolase domain protein
• strand^?: -
• coordinates^?: 3651410..3652270
• synteny block^?: BlockID0023600
• occurrence^?: in 100% of 33 strains

⊟Orthologs

COL:
SACOL1072 (folD)
N315:
SA0915 (folD)
NCTC8325:
SAOUHSC_01007
Newman:
NWMN_0932 (folD)
USA300_FPR3757:
SAUSA300_0965 (folD)
04-02981:
SA2981_1019 (folD)
08BA02176:
C248_1088 (folD)
11819-97:
MS7_1021
6850:
RSAU_000950 (folD)
71193:
ST398NM01_1061
ECT-R 2:
ECTR2_919
ED133:
SAOV_1009c
ED98:
SAAV_1028 (folD)
HO 5096 0412:
SAEMRSA15_08940 (folD)
JH1:
SaurJH1_1145
JH9:
SaurJH9_1123
JKD6008:
SAA6008_01019 (folD)
JKD6159:
SAA6159_00919 (folD)
LGA251:
SARLGA251_09770 (folD)
M013:
M013TW_0995
MRSA252:
SAR1037 (folD)
MSHR1132:
SAMSHR1132_09110
MSSA476:
SAS0999
Mu3:
SAHV_1055 (folD)
Mu50:
SAV1063 (folD)
MW2:
MW0946 (folD)
RF122:
SAB0930c (folD)
ST398:
SAPIG1061
T0131:
SAT0131_01099
TCH60:
HMPREF0772_12170 (folD)
TW20:
SATW20_10590 (folD)
USA300_TCH1516:
USA300HOU_1008 (folD)
VC40:
SAVC_04480

⊟Genome Viewer

COL
N315
NCTC8325
Newman
USA300_FPR3757

⊟Alignments

• alignment of orthologues:
  CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
  
  
  COL             MVAKILDGKQIAKDYRQGLQDQVEALKEKGFTPKLSVILVGNDGASQSYVRSKKKAAEKI
  N315            MVAKILDGKQIAKDYRQGLQDQVEALKEKGFTPKLSVILVGNDGASQSYVRSKKKAAEKI
  NCTC8325        MVAKILDGKQIAKDYRQGLQDQVEALKEKGFTPKLSVILVGNDGASQSYVRSKKKAAEKI
  Newman          MVAKILDGKQIAKDYRQGLQDQVEALKEKGFTPKLSVILVGNDGASQSYVRSKKKAAEKI
  USA300_FPR3757  MVAKILDGKQIAKDYRQGLQDQVEALKEKGFTPKLSVILVGNDGASQSYVRSKKKAAEKI
                  ************************************************************
  
  COL             GMISEIVHLEETATEEEVLNELNRLNNDDSVSGILVQVPLPKQVSEQKILEAINPEKDVD
  N315            GMISEIVHLEETATEEEVLNELNRLNNDDSVSGILVQVPLPKQVSEQKILEAINPEKDVD
  NCTC8325        GMISEIVHLEETATEEEVLNELNRLNNDDSVSGILVQVPLPKQVSEQKILEAINPEKDVD
  Newman          GMISEIVHLEETATEEEVLNELNRLNNDDSVSGILVQVPLPKQVSEQKILEAINPEKDVD
  USA300_FPR3757  GMISEIVHLEETATEEEVLNELNRLNNDDSVSGILVQVPLPKQVSEQKILEAINPEKDVD
                  ************************************************************
  
  COL             GFHPINIGKLYIDEQTFVPCTPLGIMEILKHADIDLEGKNAVVIGRSHIVGQPVSKLLLQ
  N315            GFHPINIGKLYIDEQTFVPCTPLGIMEILKHADIDLEAKNAVVIGRSHIVGQPVSKLLLQ
  NCTC8325        GFHPINIGKLYIDEQTFVPCTPLGIMEILKHADIDLEGKNAVVIGRSHIVGQPVSKLLLQ
  Newman          GFHPINIGKLYIDEQTFVPCTPLGIMEILKHADIDLEGKNAVVIGRSHIVGQPVSKLLLQ
  USA300_FPR3757  GFHPINIGKLYIDEQTFVPCTPLGIMEILKHADIDLEGKNAVVIGRSHIVGQPVSKLLLQ
                  *************************************.**********************
  
  COL             KNASVTILHSRSKDMASYLKDADVIVSAVGKPGLVTKDVVKEGAVIIDVGNTPDENGKLK
  N315            KNASVTILHSRSKDMASYLKDADVIVSAVGKPSLVTKDVVKEGAVIIDVGNTPDENGKLK
  NCTC8325        KNASVTILHSRSKDMASYLKDADVIVSAVGKPGLVTKDVVKEGAVIIDVGNTPDENGKLK
  Newman          KNASVTILHSRSKDMASYLKDADVIVSAVGKPGLVTKDVVKEGAVIIDVGNTPDENGKLK
  USA300_FPR3757  KNASVTILHSRSKDMASYLKDADVIVSAVGKPGLVTKDVVKEGAVIIDVGNTPDENGKLK
                  ********************************.***************************
  
  COL             GDVDYDAVKEIAGAITPVPGGVGPLTITMVLNNTLLAEKMRRGIDS
  N315            GDVDYDAVKEIAGAITPVPGGVGPLTITMVLNNTLLAEKMRRGIDS
  NCTC8325        GDVDYDAVKEIAGAITPVPGGVGPLTITMVLNNTLLAEKMRRGIDS
  Newman          GDVDYDAVKEIAGAITPVPGGVGPLTITMVLNNTLLAEKMRRGIDS
  USA300_FPR3757  GDVDYDAVKEIAGAITPVPGGVGPLTITMVLNNTLLAEKMRRGIDS
                  **********************************************