⊟Summary[edit | edit source]

pan ID^?: SAUPAN002608000
symbol^?: recQ1
synonym:
description^?: DNA helicase RecQ
- DNA helicase RecQ
- ATP-dependent DNA helicase RecQ
- ATP-dependent DNA helicase
- DNA helicase
- ATP-dependent helicase RecQ
- putative ATP-dependent DNA helicase
strand^?: +
coordinates^?: 3118374..3120155
synteny block^?: BlockID0018440
occurrence^?: in 100% of 34 strains

recQ (recQ1) : replication fork restart ATP-dependent DNA helicase ^[1]

DNA replication forks can occasionally stall or collapse mid-replication. Restoration of active DNA replication requires unwinding of a new replication bubble large enough for binding of replicative polymerase proteins. RecQ recognizes collapsed replication forks and remodels surrounding DNA to generate a new replication bubble.

⊟Orthologs[edit | edit source]

COL:

SACOL0780 (recQ1)

N315:

SA0676 (recQ)

NCTC8325:

SAOUHSC_00730

Newman:

NWMN_0689 (recQ)

USA300_FPR3757:

SAUSA300_0705 (recQ)

JSNZ:

JSNZ_000689 (recQ)

04-02981:

SA2981_0698 (recQ)

08BA02176:

C248_0806

11819-97:

MS7_0772 (recQ)

6850:

RSAU_000695 (recQ1)

71193:

ST398NM01_0798

ECT-R 2:

ECTR2_671 (recQ)

ED133:

SAOV_0755

ED98:

SAAV_0682 (recQ1)

HO 5096 0412:

SAEMRSA15_06470

JH1:

SaurJH1_0761

JH9:

SaurJH9_0744

JKD6008:

SAA6008_00736

JKD6159:

SAA6159_00675

LGA251:

SARLGA251_06540

M013:

M013TW_0707

MRSA252:

SAR0774

MSHR1132:

SAMSHR1132_06660

MSSA476:

SAS0686

Mu3:

SAHV_0718 (recQ)

Mu50:

SAV0721 (recQ)

MW2:

MW0683 (recQ)

RF122:

SAB0670

ST398:

SAPIG0798 (recQ)

T0131:

SAT0131_00790

TCH60:

HMPREF0772_12466 (recQ2)

TW20:

SATW20_07960

USA300_TCH1516:

USA300HOU_0744 (recQ1)

VC40:

SAVC_03235

⊟Genome Viewer[edit | edit source]

⊟Alignments[edit | edit source]

alignment of orthologues:
CLUSTAL format alignment by MAFFT L-INS-i (v7.307)

COL             MMQQTLSHYFGYETFRPGQEEIISKVLDHRNVLGVLPTGGGKSICYQVPGLLLGGTTIVI
N315            MMQQTLSHYFGYETFRPGQEEIISKVLDHRNVLGVLPTGGGKSICYQVPGLLLGGTTIVI
NCTC8325        MMQQTLSHYFGYETFRPGQEEIISKVLDHRNVLGVLPTGGGKSICYQVPGLLLGGTTIVI
Newman          MMQQTLSHYFGYETFRPGQEEIISKVLDHRNVLGVLPTGGGKSICYQVPGLLLGGTTIVI
USA300_FPR3757  MMQQTLSHYFGYETFRPGQEEIISKVLDHRNVLGVLPTGGGKSICYQVPGLLLGGTTIVI
                ************************************************************

COL             SPLISLMKDQVDQLKAMGIQAAFLNSSLTQKEQQRIEKALSNGEIQFLYVAPERFENRYF
N315            SPLISLMKDQVDQLKAMGIQAAFLNSSLTQKEQQRIEKALSNGEIQFLYVAPERFENRYF
NCTC8325        SPLISLMKDQVDQLKAMGIQAAFLNSSLTQKEQQRIEKALSNGEIQFLYVAPERFENRYF
Newman          SPLISLMKDQVDQLKAMGIQAAFLNSSLTQKEQQRIEKALSNGEIQFLYVAPERFENRYF
USA300_FPR3757  SPLISLMKDQVDQLKAMGIQAAFLNSSLTQKEQQRIEKALSNGEIQFLYVAPERFENRYF
                ************************************************************

COL             LNMLQRIKIHLVAFDEAHCISKWGHDFRPSYQNVISKVFTLPQDFTIIALTATATVEVQQ
N315            LNMLQRIKIHLVAFDEAHCISKWGHDFRPSYQNVISKVFTLPQDFTIIALTATATVEVQQ
NCTC8325        LNMLQRIKIHLVAFDEAHCISKWGHDFRPSYQNVISKVFTLPQDFTIIALTATATVEVQQ
Newman          LNMLQRIKIHLVAFDEAHCISKWGHDFRPSYQNVISKVFTLPQDFTIIALTATATVEVQQ
USA300_FPR3757  LNMLQRIKIHLVAFDEAHCISKWGHDFRPSYQNVISKVFTLPQDFTIIALTATATVEVQQ
                ************************************************************

COL             DIREKLNIAQTDQIKTSTKRRNLIFKVNPTYQRQKFILDYIKTHDEDAGIIYCSTRKQVE
N315            DIREKLNIAQTDQIKTSTKRRNLIFKVNPTYQRQKFILDYIKTHDEDAGIIYCSTRKQVE
NCTC8325        DIREKLNIAQTDQIKTSTKRRNLIFKVNPTYQRQKFILDYIKTHDEDAGIIYCSTRKQVE
Newman          DIREKLNIAQTDQIKTSTKRRNLIFKVNPTYQRQKFILDYIKTHDEDAGIIYCSTRKQVE
USA300_FPR3757  DIREKLNIAQTDQIKTSTKRRNLIFKVNPTYQRQKFILDYIKTHDEDAGIIYCSTRKQVE
                ************************************************************

COL             ELQEALESQKIESVIYHAGLSNKEREEAQNDFLFDRVKVVVATNAFGMGIDKSNVRFVIH
N315            ELQEALESQKIESVIYHAGLSNKEREEAQNDFLFDRVKVVVATNAFGMGIDKSNVRFVIH
NCTC8325        ELQEALESQKIESVIYHAGLSNKEREEAQNDFLFDRVKVVVATNAFGMGIDKSNVRFVIH
Newman          ELQEALESQKIESVIYHAGLSNKEREEAQNDFLFDRVKVVVATNAFGMGIDKSNVRFVIH
USA300_FPR3757  ELQEALESQKIESVIYHAGLSNKEREEAQNDFLFDRVKVVVATNAFGMGIDKSNVRFVIH
                ************************************************************

COL             YNMPGDLESYYQEAGRAGRDGLKSECILLFSERDINLHEYFITVSQADDDYKDKMGEKLT
N315            YNMPGDLESYYQEAGRAGRDGLKSECILLFSERDINLHEYFITVSQADDDYKDKMGEKLT
NCTC8325        YNMPGDLESYYQEAGRAGRDGLKSECILLFSERDINLHEYFITVSQADDDYKDKMGEKLT
Newman          YNMPGDLESYYQEAGRAGRDGLKSECILLFSERDINLHEYFITVSQADDDYKDKMGEKLT
USA300_FPR3757  YNMPGDLESYYQEAGRAGRDGLKSECILLFSERDINLHEYFITVSQADDDYKDKMGEKLT
                ************************************************************

COL             KMIQYTKTKKCLEATIVHYFEPNEKLEECEQCSNCVQQDKSYNMTQEAKMIISCIARMKQ
N315            KMIQYTKTKKCLEATIVHYFEPNEKLEECEQCSNCVQQDKSYNMTQEAKMIISCIARMKQ
NCTC8325        KMIQYTKTKKCLEATIVHYFEPNEKLEECEQCSNCVQQDKSYNMTQEAKMIISCIARMKQ
Newman          KMIQYTKTKKCLEATIVHYFEPNEKLEECEQCSNCVQQDKSYNMTQEAKMIISCIARMKQ
USA300_FPR3757  KMIQYTKTKKCLEATIVHYFEPNEKLEECEQCSNCVQQDKSYNMTQEAKMIISCIARMKQ
                ************************************************************

COL             QESYSVIIQVLRGESTDYIKYKGYDQISTHGLMKGYTTSELSHLIDELRFKGFLNENDEI
N315            QESYSVIIQVLRGESTDYIKYKGYDQISTHGLMKGYTTSELSHLIDELRFKGFLNENDEI
NCTC8325        QESYSVIIQVLRGESTDYIKYKGYDQISTHGLMKGYTTSELSHLIDELRFKGFLNENDEI
Newman          QESYSVIIQVLRGESTDYIKYKGYDQISTHGLMKGYTTSELSHLIDELRFKGFLNENDEI
USA300_FPR3757  QESYSVIIQVLRGESTDYIKYKGYDQISTHGLMKGYTTSELSHLIDELRFKGFLNENDEI
                ************************************************************

COL             LMCDTSIKKLLSNEVEVFTTPFKQKATEKVFINTVEGVDRVLFSQLVEVRKKLSDKLTIA
N315            LMCDTSIKKLLSNEVEVFTTPFKQKATEKVFINTVEGVDRVLFSQLVEVRKKLSDKLTIA
NCTC8325        LMCDTSIKKLLSNEVEVFTTPFKQKATEKVFINTVEGVDRVLFSQLVEVRKKLSDKLTIA
Newman          LMCDTSIKKLLSNEVEVFTTPFKQKATEKVFINTVEGVDRVLFSQLVEVRKKLSDKLTIA
USA300_FPR3757  LMCDTSIKKLLSNEVEVFTTPFKQKATEKVFINTVEGVDRVLFSQLVEVRKKLSDKLTIA
                ************************************************************

COL             PVSIFSDYTLEEFAKRKPASKQDMINIDGVGSYKLKHYCPAFLETIQNYKAKV
N315            PVSIFSDYTLEEFAKRKPASKQDMINIDGVGSYKLKHYCPAFLETIQNYKAKV
NCTC8325        PVSIFSDYTLEEFAKRKPASKQDMINIDGVGSYKLKHYCPAFLETIQNYKAKV
Newman          PVSIFSDYTLEEFAKRKPASKQDMINIDGVGSYKLKHYCPAFLETIQNYKAKV
USA300_FPR3757  PVSIFSDYTLEEFAKRKPASKQDMINIDGVGSYKLKHYCPAFLETIQNYKAKV
                *****************************************************

↑ Kaiying Cheng, Yukang Sun, Huan Yu, Yingxuan Hu, Yini He, Yuanyuan Shen
Staphylococcus aureus SOS response: Activation, impact, and drug targets.
mLife: 2024, 3(3);343-366
[PubMed:39359682] [WorldCat.org] [DOI] (I e)Wei Qin, Na-Nv Liu, Lijun Wang, Min Zhou, Hua Ren, Elisabeth Bugnard, Jie-Lin Liu, Lin-Hu Zhang, Jeremie Vendôme, Jin-Shan Hu, Xu Guang Xi
Characterization of biochemical properties of Bacillus subtilis RecQ helicase.
J Bacteriol: 2014, 196(24);4216-28
[PubMed:25246477] [WorldCat.org] [DOI] (I p)

[1] Kaiying Cheng, Yukang Sun, Huan Yu, Yingxuan Hu, Yini He, Yuanyuan Shen
Staphylococcus aureus SOS response: Activation, impact, and drug targets.
mLife: 2024, 3(3);343-366
[PubMed:39359682] [WorldCat.org] [DOI] (I e)Wei Qin, Na-Nv Liu, Lijun Wang, Min Zhou, Hua Ren, Elisabeth Bugnard, Jie-Lin Liu, Lin-Hu Zhang, Jeremie Vendôme, Jin-Shan Hu, Xu Guang Xi
Characterization of biochemical properties of Bacillus subtilis RecQ helicase.
J Bacteriol: 2014, 196(24);4216-28
[PubMed:25246477] [WorldCat.org] [DOI] (I p)

[1]

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Contents

⊟Summary[edit | edit source]

⊟Orthologs[edit | edit source]

⊟Genome Viewer[edit | edit source]

⊟Alignments[edit | edit source]

COL
N315
NCTC8325
Newman
USA300_FPR3757
JSNZ

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⊟Summary[edit | edit source]

⊟Orthologs[edit | edit source]

⊟Genome Viewer[edit | edit source]

⊟Alignments[edit | edit source]