Jump to navigation
Jump to search
⊟Summary[edit | edit source]
- pan ID?: SAUPAN001065000
- symbol?: malE
- synonym:
- description?: maltose ABC transporter substrate-binding protein
- maltose ABC transporter substrate-binding protein
- extracellular solute-binding protein
- maltodextrin ABC transporter substrate-binding protein
- maltose ABC transporter, substrate binding protein
- maltose ABC transporter maltose-binding protein
- putative maltose ABC transporter maltose-binding protein
- Maltose/maltodextrin ABC transporter, substrate binding periplasmic protein MalE
- putative extracellular sugar-binding lipoprotein
- ABC transporter substrate-binding protein
- bacterial extracellular solute-binding family protein
- extracellular solute-binding family protein
- Extracellular solute-binding protein, family 1
- maltose/maltodextrin ABC superfamily ATP binding cassette transporter, binding protein
- Maltose/maltodextrin-binding protein
- maltose/maltodextrin transport system
- maltose/maltodextrin transport system protein
- maltose ABC transporter, maltose-binding protein, putative
descriptions from strain specific annotations:
- strand?: +
- coordinates?: 1342233..1343504
- synteny block?: BlockID0005870
- occurrence?: in 100% of 34 strains
malE : maltodextrin transport system substrate-binding protein [1]
• A crystal structure is available : 4HS7
The nomenclature of the malKEFG ATP transport system is inconsistently applied across organisms. By convention, MalK is the ATPase and MalE is the substrate binding protein. However, nomenclature for the ATPase (i.e. MsmK, MsmX) as well as the permease components (i.e. MalC, malD) is not consistently applied in E. coli, B. subtilis, S. pneumoniae and E. faecalis.
⊟Orthologs[edit | edit source]
04-02981:
SA2981_0215
08BA02176:
C248_0198
11819-97:
MS7_0200
6850:
RSAU_000158
71193:
ST398NM01_0224
ECT-R 2:
ECTR2_175
ED133:
SAOV_0152
ED98:
SAAV_0180
HO 5096 0412:
SAEMRSA15_01730
JH1:
SaurJH1_0205
JH9:
SaurJH9_0199
JKD6008:
SAA6008_00183
JKD6159:
SAA6159_00189
JSNZ:
JSNZ_000151
LGA251:
SARLGA251_01780
M013:
M013TW_0194
MRSA252:
SAR0206
MSHR1132:
SAMSHR1132_01800
MSSA476:
SAS0190
Mu3:
SAHV_0213
Mu50:
SAV0214
MW2:
MW0190
RF122:
SAB0152
ST398:
SAPIG0224
T0131:
SAT0131_00199 (grpE)
TCH60:
HMPREF0772_10293
TW20:
SATW20_02150
USA300_TCH1516:
USA300HOU_0221
VC40:
SAVC_00810
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MSKILKCITLAVVMLLIVTACGPNRSKEDIDKALNKDNSKDKPNQLTMWVDGDKQMAFYK
N315 MSKILKCITLAVVMLLIVTACGPNRSKEDIDKALNKDNSKDKPNQLTMWVDGDKQMAFYK
NCTC8325 MSKILKCITLAVVMLLIVTACGPNRSKEDIDKALNKDNSKDKPNQLTMWVDGDKQMAFYK
Newman MSKILKCITLAVVMLLIVTACGPNRSKEDIDKALNKDNSKDKPNQLTMWVDGDKQMAFYK
USA300_FPR3757 MSKILKCITLAVVMLLIVTACGPNRSKEDIDKALNKDNSKDKPNQLTMWVDGDKQMAFYK
************************************************************
COL KITDQYTKKTGIKVKLVNIGQNDQLENISLDAPAGKGPDIFFLAHDNTGSAYLQGLAAEI
N315 KITDQYTKKTGIKVKLVNIGQNDQLENISLDAPAGKGPDIFFLAHDNTGSAYLQGLAAEI
NCTC8325 KITDQYTKKTGIKVKLVNIGQNDQLENISLDAPAGKGPDIFFLAHDNTGSAYLQGLAAEI
Newman KITDQYTKKTGIKVKLVNIGQNDQLENISLDAPAGKGPDIFFLAHDNTGSAYLQGLAAEI
USA300_FPR3757 KITDQYTKKTGIKVKLVNIGQNDQLENISLDAPAGKGPDIFFLAHDNTGSAYLQGLAAEI
************************************************************
COL KLSKDELKGFNKQALKAMNYDNKQLALPAIVETTALFYNKKLVKNAPQTLEEVEANAAKL
N315 KLSKDELKGFNKQALKAMNYDNKQLALPAIVETTALFYNKKLVKNAPQTLEEVEANAAKL
NCTC8325 KLSKDELKGFNKQALKAMNYDNKQLALPAIVETTALFYNKKLVKNAPQTLEEVEANAAKL
Newman KLSKDELKGFNKQALKAMNYDNKQLALPAIVETTALFYNKKLVKNAPQTLEEVEANAAKL
USA300_FPR3757 KLSKDELKGFNKQALKAMNYDNKQLALPAIVETTALFYNKKLVKNAPQTLEEVEANAAKL
************************************************************
COL TDSKKKQYGMLFDAKNFYFNYPFLFGNDDYIFKKNGSEYDIHQLGLNSKHVVKNAERLQK
N315 TDSKKKQYGMLFDAKNFYFNYPFLFGNDDYIFKKNGSEYDIHQLGLNSKHVVKNAERLQK
NCTC8325 TDSKKKQYGMLFDAKNFYFNYPFLFGNDDYIFKKNGSEYDIHQLGLNSKHVVKNAERLQK
Newman TDSKKKQYGMLFDAKNFYFNYPFLFGNDDYIFKKNGSEYDIHQLGLNSKHVVKNAERLQK
USA300_FPR3757 TDSKKKQYGMLFDAKNFYFNYPFLFGNDDYIFKKNGSEYDIHQLGLNSKHVVKNAERLQK
************************************************************
COL WYDKGYLPKAATHDVMIGLFKEGKVGQFVTGPWNINEYQETFGKDLGVTTLPTDGGKPMK
N315 WYDKGYLPKAATHDVMIGLFKEGKVGQFVTGPWNINEYQETFGKDLGVTTLPTDGGKPMK
NCTC8325 WYDKGYLPKAATHDVMIGLFKEGKVGQFVTGPWNINEYQETFGKDLGVTTLPTDGGKPMK
Newman WYDKGYLPKAATHDVMIGLFKEGKVGQFVTGPWNINEYQETFGKDLGVTTLPTDGGKPMK
USA300_FPR3757 WYDKGYLPKAATHDVMIGLFKEGKVGQFVTGPWNINEYQETFGKDLGVTTLPTDGGKPMK
************************************************************
COL PFLGVRGWYLSEYSKHKYWAKDLMLYITSKDTLQKYTDEMSEITGRVDVKSSNPNLKVFE
N315 PFLGVRGWYLSEYSKHKYWAKDLMLYITSKDTLQKYTDEMSEITGRVDVKSSNPNLKVFE
NCTC8325 PFLGVRGWYLSEYSKHKYWAKDLMLYITSKDTLQKYTDEMSEITGRVDVKSSNPNLKVFE
Newman PFLGVRGWYLSEYSKHKYWAKDLMLYITSKDTLQKYTDEMSEITGRVDVKSSNPNLKVFE
USA300_FPR3757 PFLGVRGWYLSEYSKHKYWAKDLMLYITSKDTLQKYTDEMSEITGRVDVKSSNPNLKVFE
************************************************************
COL KQARHAEPMPNIPEMRQVWEPMGNASIFISNGKNPKQALDEATNDITQNIKILHPSQNDK
N315 KQARHAEPMPNIPEMRQVWEPMGNASIFISNGKNPKQALDEATNDITQNIKILHPSQNDK
NCTC8325 KQARHAEPMPNIPEMRQVWEPMGNASIFISNGKNPKQALDEATNDITQNIKILHPSQNDK
Newman KQARHAEPMPNIPEMRQVWEPMGNASIFISNGKNPKQALDEATNDITQNIKILHPSQNDK
USA300_FPR3757 KQARHAEPMPNIPEMRQVWEPMGNASIFISNGKNPKQALDEATNDITQNIKILHPSQNDK
************************************************************
COL KGD
N315 KGD
NCTC8325 KGD
Newman KGD
USA300_FPR3757 KGD
***
- ↑ Kiyoko Takemiya, Shelly Wang, Yu Liu, Niren Murthy, Mark M Goodman, W Robert Taylor
Isothermal titration calorimetry analysis of the binding between the maltodextrin binding protein malE of Staphylococcus aureus with maltodextrins of various lengths.
Biochem Biophys Res Commun: 2024, 695;149467
[PubMed:38211531] [WorldCat.org] [DOI] (I p)