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⊟Summary[edit | edit source]
- pan ID?: SAUPAN001036000
- symbol?: murR
- synonym:
- description?: MurR/RpiR family transcriptional regulator
- MurR/RpiR family transcriptional regulator
- transcriptional regulator
- putative transcriptional regulator RpiR family
- RpiR family phosphosugar-binding transcriptional regulator
- helix-turn-helix domain, rpiR family protein
- phosphosugar-binding transcriptional regulator, RpiR family
- RpiR family transcripitonal regulator
- RpiR family transcriptional regulator
- RpiR family transcription regulator
- Sialic acid utilization regulator, RpiR family
- Transcriptional regulator, RpiR family
- transcription regulator RpiR family
descriptions from strain specific annotations:
- strand?: +
- coordinates?: 1311372..1312250
- synteny block?: BlockID0005630
- occurrence?: in 100% of 33 strains
murR: MurNAc-GlcNAc turnover transcriptional repressor MurR [1]
• "MurNAc-GlcNAc" also called "N-acetylmuramate" refers to the disaccharide N-acetylmuramic acid-β-1,4-N-acetylglucosamine
• MurR has a consensus DNA binding motif of: 5'-ATTGTAAwnnnwTTACAAT-3'
• The MurR Regulon consists of Four Genes
⊟Orthologs[edit | edit source]
04-02981:
SA2981_0194
08BA02176:
C248_0185
11819-97:
MS7_0186
6850:
RSAU_000145
71193:
ST398NM01_0211
ECT-R 2:
ECTR2_156
ED133:
SAOV_0138
ED98:
SAAV_0162
HO 5096 0412:
SAEMRSA15_01580
JH1:
SaurJH1_0183
JH9:
SaurJH9_0178
JKD6008:
SAA6008_00172
JKD6159:
SAA6159_00175
LGA251:
SARLGA251_01640
M013:
M013TW_0181
MRSA252:
SAR0194
MSHR1132:
SAMSHR1132_01680
MSSA476:
SAS0168
Mu3:
SAHV_0192
Mu50:
SAV0193
MW2:
MW0167
RF122:
SAB0133
ST398:
SAPIG0211
T0131:
SAT0131_00188
TCH60:
HMPREF0772_10305
TW20:
SATW20_02030
USA300_TCH1516:
USA300HOU_0207
VC40:
SAVC_00735
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL -MTNILYRIDKQLSDFTKTEKIIADYILKNPHKIIDMTVNDLADVTNVSTASIVRFSRKM
N315 -MTNILYRIDKQLSDFTKTEKIIADYILKNPHKIIDMTVNDLADVTNVSTASIVRFSRKM
NCTC8325 -MTNILYRIDKQLSDFTKTEKIIADYILKNPHKIIDMTVNDLADVTNVSTASIVRFSRKM
Newman MMTNILYRIDKQLSDFTKTEKIIADYILKNPHKIIDMTVNDLADVTNVSTASIVRFSRKM
USA300_FPR3757 -MTNILYRIDKQLSDFTKTEKIIADYILKNPHKIIDMTVNDLADVTNVSTASIVRFSRKM
***********************************************************
COL THQGFQELKIAISRYLPEDIATNPHLELIENESVETLKNKMIARATNTMRFVATNIMDAQ
N315 THQGFQELKIAISRYLPEDIATNPHLELIENESVETLKNKMIARATNTMRFVATNIMDAQ
NCTC8325 THQGFQELKIAISRYLPEDIATNPHLELIENESVETLKNKMIARATNTMRFVATNIMDAQ
Newman THQGFQELKIAISRYLPEDIATNPHLELIENESVETLKNKMIARATNTMRFVATNIMDAQ
USA300_FPR3757 THQGFQELKIAISRYLPEDIATNPHLELIENESVETLKNKMIARATNTMRFVATNIMDAQ
************************************************************
COL IDAICDVLKNARTIFLFGFGASSLTIGDLFQKLSRIGLNVRLLHETHLLVSTFATHDDRD
N315 IDAICDVLKNARTIFLFGFGASSLTIGDLFQKLSRIGLNVRLLHETHLLVSTFATHDDRD
NCTC8325 IDAICDVLKNARTIFLFGFGASSLTIGDLFQKLSRIGLNVRLLHETHLLVSTFATHDDRD
Newman IDAICDVLKNARTIFLFGFGASSLTIGDLFQKLSRIGLNVRLLHETHLLVSTFATHDDRD
USA300_FPR3757 IDAICDVLKNARTIFLFGFGASSLTIGDLFQKLSRIGLNVRLLHETHLLVSTFATHDDRD
************************************************************
COL CMIFVTNQGSHSELQSIAQVATHYSIPIITISSTANNPVAQIADYALIYGRTDENEMRMA
N315 CMIFVTNQGSHSELQSIAQVATHYSIPIITISSTANNPVAQIADYALIYGRTDENEMRMA
NCTC8325 CMIFVTNQGSHSELQSIAQVATHYSIPIITISSTANNPVAQIADYALIYGRTDENEMRMA
Newman CMIFVTNQGSHSELQSIAQVATHYSIPIITISSTANNPVAQIADYALIYGRTDENEMRMA
USA300_FPR3757 CMIFVTNQGSHSELQSIAQVATHYSIPIITISSTANNPVAQIADYALIYGRTDENEMRMA
************************************************************
COL ATTSLFAQLFTVDILYYRFVALNYHAILDCITQSKMALDNYRKHLATIDFKH
N315 ATTSLFAQLFTVDILYYRFVALNYHAILDCITQSKMALDNYRKHLATIDFKH
NCTC8325 ATTSLFAQLFTVDILYYRFVALNYHAILDCITQSKMALDNYRKHLATIDFKH
Newman ATTSLFAQLFTVDILYYRFVALNYHAILDCITQSKMALDNYRKHLATIDFKH
USA300_FPR3757 ATTSLFAQLFTVDILYYRFVALNYHAILDCITQSKMALDNYRKHLATIDFKH
****************************************************
- ↑ Robert Maria Kluj, Patrick Ebner, Martina Adamek, Nadine Ziemert, Christoph Mayer, Marina Borisova
Recovery of the Peptidoglycan Turnover Product Released by the Autolysin Atl in Staphylococcus aureus Involves the Phosphotransferase System Transporter MurP and the Novel 6-phospho-N-acetylmuramidase MupG.
Front Microbiol: 2018, 9;2725
[PubMed:30524387] [WorldCat.org] [DOI] (P e)Yefei Zhu, Renu Nandakumar, Marat R Sadykov, Nandakumar Madayiputhiya, Thanh T Luong, Rosmarie Gaupp, Chia Y Lee, Greg A Somerville
RpiR homologues may link Staphylococcus aureus RNAIII synthesis and pentose phosphate pathway regulation.
J Bacteriol: 2011, 193(22);6187-96
[PubMed:21926234] [WorldCat.org] [DOI] (I p)