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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159JSNZLGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40
⊟Summary[edit | edit source]
- pan ID?: SAUPAN000814000
- symbol?: arcA
- synonym:
- description?: arginine deiminase
- strand?: -
- coordinates?: 1049132..1050367
- synteny block?: BlockID0003920
- occurrence?: in 6% of 34 strains
arcAa (arcAACME) : arginine catabolic mobile element arginine deiminase [1]
• this version of arginine deiminase is found in the Arginine Catabolic Mobile Element (ACME) that is sometimes found alongside the SCCmec cassette, particularly in USA300 MRSA strains. It encodes an arginine deiminase pathway that is actively transcribed during anaerobic growth, increasing the virulence of this clade. The "a" after "arcA" is to differentiate this version from the constitutive "c" version found in the core staphylococcal genome.
⊟Orthologs[edit | edit source]
COL:
—
N315:
—
NCTC8325:
—
04-02981:
—
08BA02176:
—
11819-97:
—
6850:
—
71193:
—
ECT-R 2:
—
ED133:
—
ED98:
—
HO 5096 0412:
—
JH1:
—
JH9:
—
JKD6008:
—
JKD6159:
—
JSNZ:
—
LGA251:
—
M013:
—
MRSA252:
—
MSHR1132:
—
MSSA476:
—
Mu3:
—
Mu50:
—
MW2:
—
RF122:
—
ST398:
—
T0131:
—
TCH60:
—
TW20:
—
USA300_TCH1516:
USA300HOU_0070 (arcA1)
VC40:
—
⊟Genome Viewer[edit | edit source]
⊟Alignments[edit | edit source]
- alignment of orthologues:
- ↑ Zayda Lorena Corredor Rozo, Ricaurte Alejandro Márquez-Ortiz, Betsy Esperanza Castro, Natasha Vanegas Gómez, Javier Escobar-Pérez
Participation of the arcRACME protein in self-activation of the arc operon located in the arginine catabolism mobile element in pandemic clone USA300.
Mem Inst Oswaldo Cruz: 2017, 112(7);499-503
[PubMed:28591311] [WorldCat.org] [DOI] (I p)