PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

⊟Summary

• pan ID^?: SAUPAN000101000
• symbol^?: mecA
• synonym:
• description^?: PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA

  descriptions from strain specific annotations:

  • PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA
  • penicillin-binding protein 2'
  • penicillin binding protein 2 prime
  • beta-lactam-inducible penicillin-binding protein
  • penicillin-binding protein 3 (pbp 3) (pspb20)
  • penicillin-binding protein PBP2a, methicillin resistance determinant MecA
  • Penicillin-binding protein PBP2a, methicillin resistance determinant MecA, transpeptidase
  • peptidoglycan glycosyltransferase
• strand^?: -
• coordinates^?: 118573..120700
• synteny block^?: BlockID0000790
• occurrence^?: in 70% of 33 strains

⊟Orthologs

COL:
SACOL0033 (mecA)
N315:
SA0038 (mecA)
NCTC8325:
—
Newman:
—
USA300_FPR3757:
SAUSA300_0032 (mecA)
04-02981:
SA2981_0039 (mecA)
08BA02176:
C248_0036 (mecA)
11819-97:
MS7_0033 (mecA)
6850:
—
71193:
—
ECT-R 2:
—
ED133:
—
ED98:
—
HO 5096 0412:
SAEMRSA15_00310 (mecA)
JH1:
SaurJH1_0029
JH9:
SaurJH9_0029
JKD6008:
SAA6008_00039 (mecA)
JKD6159:
SAA6159_00031 (mecA)
LGA251:
SARLGA251_00260 (mecA)
M013:
M013TW_0045
MRSA252:
SAR0039 (mecA)
MSHR1132:
SAMSHR1132_00320
MSSA476:
—
Mu3:
SAHV_0040 (mecA)
Mu50:
SAV0041 (mecA)
MW2:
MW0031 (mecA)
RF122:
—
ST398:
SAPIG0042
T0131:
SAT0131_00034 (recF)
TCH60:
HMPREF0772_10435 (mecA)
TW20:
SATW20_00740 (mecA)
USA300_TCH1516:
USA300HOU_0031 (mecA)
VC40:
—

⊟Genome Viewer

COL
N315
USA300_FPR3757

⊟Alignments

• alignment of orthologues:
  CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
  
  
  COL             MKKIKIVPLILIVVVVGFGIYFYASKDKEINNTIDAIEDKNFKQVYKDSSYISKSDNGEV
  N315            MKKIKIVPLILIVVVVGFGIYFYASKDKEINNTIDAIEDKNFKQVYKDSSYISKSDNGEV
  USA300_FPR3757  MKKIKIVPLILIVVVVGFGIYFYASKDKEINNTIDAIEDKNFKQVYKDSSYISKSDNGEV
                  ************************************************************
  
  COL             EMTERPIKIYNSLGVKDINIQDRKIKKVSKNKKRVDAQYKIKTNYGNIDRNVQFNFVKED
  N315            EMTERPIKIYNSLGVKDINIQDRKIKKVSKNKKRVDAQYKIKTNYGNIDRNVQFNFVKED
  USA300_FPR3757  EMTERPIKIYNSLGVKDINIQDRKIKKVSKNKKRVDAQYKIKTNYGNIDRNVQFNFVKED
                  ************************************************************
  
  COL             GMWKLDWDHSVIIPGMQKDQSIHIENLKSERGKILDRNNVELANTGTAYEIGIVPKNVSK
  N315            GMWKLDWDHSVIIPGMQKDQSIHIENLKSERGKILDRNNVELANTGTAYEIGIVPKNVSK
  USA300_FPR3757  GMWKLDWDHSVIIPGMQKDQSIHIENLKSERGKILDRNNVELANTGTAYEIGIVPKNVSK
                  ************************************************************
  
  COL             KDYKAIAKELSISEDYIKQQMDQNWVQDDTFVPLKTVKKMDEYLSDFAKKFHLTTNETES
  N315            KDYKAIAKELSISEDYIKQQMDQNWVQDDTFVPLKTVKKMDEYLSDFAKKFHLTTNETES
  USA300_FPR3757  KDYKAIAKELSISEDYIKQQMDQNWVQDDTFVPLKTVKKMDEYLSDFAKKFHLTTNETES
                  ************************************************************
  
  COL             RNYPLEKATSHLLGYVGPINSEELKQKEYKGYKDDAVIGKKGLEKLYDKKLQHEDGYRVT
  N315            RNYPLGKATSHLLGYVGPINSEELKQKEYKGYKDDAVIGKKGLEKLYDKKLQHEDGYRVT
  USA300_FPR3757  RNYPLGKATSHLLGYVGPINSEELKQKEYKGYKDDAVIGKKGLEKLYDKKLQHEDGYRVT
                  ***** ******************************************************
  
  COL             IVDDNSNTIAHTLIEKKKKDGKDIQLTIDAKVQKSIYNNMKNDYGSGTAIHPQTGELLAL
  N315            IVDDNSNTIAHTLIEKKKKDGKDIQLTIDAKVQKSIYNNMKNDYGSGTAIHPQTGELLAL
  USA300_FPR3757  IVDDNSNTIAHTLIEKKKKDGKDIQLTIDAKVQKSIYNNMKNDYGSGTAIHPQTGELLAL
                  ************************************************************
  
  COL             VSTPSYDVYPFMYGMSNEEYNKLTEDKKEPLLNKFQITTSPGSTQKILTAMIGLNNKTLD
  N315            VSTPSYDVYPFMYGMSNEEYNKLTEDKKEPLLNKFQITTSPGSTQKILTAMIGLNNKTLD
  USA300_FPR3757  VSTPSYDVYPFMYGMSNEEYNKLTEDKKEPLLNKFQITTSPGSTQKILTAMIGLNNKTLD
                  ************************************************************
  
  COL             DKTSYKIDGKGWQKDKSWGGYNVTRYEVVNGNIDLKQAIESSDNIFFARVALELGSKKFE
  N315            DKTSYKIDGKGWQKDKSWGGYNVTRYEVVNGNIDLKQAIESSDNIFFARVALELGSKKFE
  USA300_FPR3757  DKTSYKIDGKGWQKDKSWGGYNVTRYEVVNGNIDLKQAIESSDNIFFARVALELGSKKFE
                  ************************************************************
  
  COL             KGMKKLGVGEDIPSDYPFYNAQISNKNLDNEILLADSGYGQGEILINPVQILSIYSALEN
  N315            KGMKKLGVGEDIPSDYPFYNAQISNKNLDNEILLADSGYGQGEILINPVQILSIYSALEN
  USA300_FPR3757  KGMKKLGVGEDIPSDYPFYNAQISNKNLDNEILLADSGYGQGEILINPVQILSIYSALEN
                  ************************************************************
  
  COL             NGNINAPHLLKDTKNKVWKKNIISKENINLLTDGMQQVVNKTHKEDIYRSYANLIGKSGT
  N315            NGNINAPHLLKDTKNKVWKKNIISKENINLLTDGMQQVVNKTHKEDIYRSYANLIGKSGT
  USA300_FPR3757  NGNINAPHLLKDTKNKVWKKNIISKENINLLTDGMQQVVNKTHKEDIYRSYANLIGKSGT
                  ************************************************************
  
  COL             AELKMKQGETGRQIGWFISYDKDNPNMMMAINVKDVQDKGMASYNAKISGKVYDELYENG
  N315            AELKMKQGETGRQIGWFISYDKDNPNMMMAINVKDVQDKGMASYNAKISGKVYDELYENG
  USA300_FPR3757  AELKMKQGETGRQIGWFISYDKDNPNMMMAINVKDVQDKGMASYNAKISGKVYDELYENG
                  ************************************************************
  
  COL             NKKYDIDE
  N315            NKKYDIDE
  USA300_FPR3757  NKKYDIDE
                  ********