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⊟Summary[edit | edit source]
- pan ID?: SAUPAN000017000
- symbol?: serS
- synonym:
- description?: serine--tRNA ligase
- serine--tRNA ligase
- seryl-tRNA synthetase
descriptions from strain specific annotations:
- strand?: +
- coordinates?: 18640..19926
- synteny block?: BlockID0000140
- occurrence?: in 100% of 34 strains
serS : seryl-tRNA synthetase [1]
• A crystal structure is available : 6R1N
⊟Orthologs[edit | edit source]
04-02981:
SA2981_0009 (serS)
08BA02176:
C248_0009 (serS)
11819-97:
MS7_0009 (serS)
6850:
RSAU_000009 (serS)
71193:
ST398NM01_0009
ECT-R 2:
ECTR2_9 (serS)
ED133:
SAOV_0009 (serS)
ED98:
SAAV_0010 (serS)
HO 5096 0412:
SAEMRSA15_00090 (serS)
JH1:
SaurJH1_0009
JH9:
SaurJH9_0009
JKD6008:
SAA6008_00009 (serS)
JKD6159:
SAA6159_00009 (serS)
JSNZ:
JSNZ_000009 (serS)
LGA251:
SARLGA251_00090 (serS)
M013:
M013TW_0010
MRSA252:
SAR0009 (serS)
MSHR1132:
SAMSHR1132_00090
MSSA476:
SAS0009
Mu3:
SAHV_0009 (serS)
Mu50:
SAV0009 (serS)
MW2:
MW0009 (serS)
RF122:
SAB0009 (serS)
ST398:
SAPIG0009 (serS)
T0131:
SAT0131_00010
TCH60:
HMPREF0772_10459 (serS)
TW20:
SATW20_00090 (serS)
USA300_TCH1516:
USA300HOU_0009 (serS)
VC40:
SAVC_00045
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MLDIRLFRNEPDTVKSKIELRGDDPKVVDEILELDEQRRKLISATEEMKARRNKVSEEIA
N315 MLDIRLFRNEPDTVKSKIELRGDDPKVVDEILELDEQRRKLISATEEMKARRNKVSEEIA
NCTC8325 MLDIRLFRNEPDTVKSKIELRGDDPKVVDEILELDEQRRKLISATEEMKARRNKVSEEIA
Newman MLDIRLFRNEPDTVKSKIELRGDDPKVVDEILELDEQRRKLISATEEMKARRNKVSEEIA
USA300_FPR3757 MLDIRLFRNEPDTVKSKIELRGDDPKVVDEILELDEQRRKLISATEEMKARRNKVSEEIA
************************************************************
COL LKKRNKENADDVIAEMRTLGDDIKEKDSQLNEIDNKMTGILCRIPNLISDDVPQGESDED
N315 LKKRNKENADDVIAEMRTLGDDIKEKDSQLNEIDNKMTGILCRIPNLISDDVPQGESDED
NCTC8325 LKKRNKENADDVIAEMRTLGDDIKEKDSQLNEIDNKMTGILCRIPNLISDDVPQGESDED
Newman LKKRNKENADDVIAEMRTLGDDIKEKDSQLNEIDNKMTGILCRIPNLISDDVPQGESDED
USA300_FPR3757 LKKRNKENADDVIAEMRTLGDDIKEKDSQLNEIDNKMTGILCRIPNLISDDVPQGESDED
************************************************************
COL NVEVKKWGTPREFSFEPKAHWDIVEELKMADFDRAAKVSGARFVYLTNEGAQLERALMNY
N315 NVEVKKWGTPREFSFEPKAHWDIVEELKMADFDRAAKVSGARFVYLTNEGAQLERALMNY
NCTC8325 NVEVKKWGTPREFSFEPKAHWDIVEELKMADFDRAAKVSGARFVYLTNEGAQLERALMNY
Newman NVEVKKWGTPREFSFEPKAHWDIVEELKMADFDRAAKVSGARFVYLTNEGAQLERALMNY
USA300_FPR3757 NVEVKKWGTPREFSFEPKAHWDIVEELKMADFDRAAKVSGARFVYLTNEGAQLERALMNY
************************************************************
COL MITKHTTQHGYTEMMVPQLVNADTMYGTGQLPKFEEDLFKVEKEGLYTIPTAEVPLTNFY
N315 MITKHTTQHGYTEMMVPQLVNADTMYGTGQLPKFEEDLFKVEKEGLYTIPTAEVPLTNFY
NCTC8325 MITKHTTQHGYTEMMVPQLVNADTMYGTGQLPKFEEDLFKVEKEGLYTIPTAEVPLTNFY
Newman MITKHTTQHGYTEMMVPQLVNADTMYGTGQLPKFEEDLFKVEKEGLYTIPTAEVPLTNFY
USA300_FPR3757 MITKHTTQHGYTEMMVPQLVNADTMYGTGQLPKFEEDLFKVEKEGLYTIPTAEVPLTNFY
************************************************************
COL RNEIIQPGVLPEKFTGQSACFRSEAGSAGRDTRGLIRLHQFDKVEMVRFEQPEDSWNALE
N315 RNEIIQPGVLPEKFTGQSACFRSEAGSAGRDTRGLIRLHQFDKVEMVRFEQPEDSWNALE
NCTC8325 RNEIIQPGVLPEKFTGQSACFRSEAGSAGRDTRGLIRLHQFDKVEMVRFEQPEDSWNALE
Newman RNEIIQPGVLPEKFTGQSACFRSEAGSAGRDTRGLIRLHQFDKVEMVRFEQPEDSWNALE
USA300_FPR3757 RNEIIQPGVLPEKFTGQSACFRSEAGSAGRDTRGLIRLHQFDKVEMVRFEQPEDSWNALE
************************************************************
COL EMTTNAEAILEELGLPYRRVILCTGDIGFSASKTYDLEVWLPSYNDYKEISSCSNCTDFQ
N315 EMTTNAEAILEELGLPYRRVILCTGDIGFSASKTYDIEVWLPSYNDYKEISSCSNCTDFQ
NCTC8325 EMTTNAEAILEELGLPYRRVILCTGDIGFSASKTYDLEVWLPSYNDYKEISSCSNCTDFQ
Newman EMTTNAEAILEELGLPYRRVILCTGDIGFSASKTYDLEVWLPSYNDYKEISSCSNCTDFQ
USA300_FPR3757 EMTTNAEAILEELGLPYRRVILCTGDIGFSASKTYDLEVWLPSYNDYKEISSCSNCTDFQ
************************************:***********************
COL ARRANIRFKRDKAAKPELAHTLNGSGLAVGRTFAAIVENYQNEDGTVTIPEALVPFMGGK
N315 ARRANIRFKRDKAAKPELAHTLNGSGLAVGRTFAAIVENYQNEDGTVTIPEALVPFMGGK
NCTC8325 ARRANIRFKRDKAAKPELAHTLNGSGLAVGRTFAAIVENYQNEDGTVTIPEALVPFMGGK
Newman ARRANIRFKRDKAAKPELAHTLNGSGLAVGRTFAAIVENYQNEDGTVTIPEALVPFMGGK
USA300_FPR3757 ARRANIRFKRDKAAKPELAHTLNGSGLAVGRTFAAIVENYQNEDGTVTIPEALVPFMGGK
************************************************************
COL TQISKPVK
N315 TQISKPVK
NCTC8325 TQISKPVK
Newman TQISKPVK
USA300_FPR3757 TQISKPVK
********
- ↑ N Bausch, L Seignovert, M Beaulande, R Leberman, M Härtlein
Analysis and overexpression in Escherichia coli of a staphylococcal gene encoding seryl-tRNA synthetase.
Biochim Biophys Acta: 1998, 1397(2);169-74
[PubMed:9565680] [WorldCat.org] [DOI] (P p)Oliver A Battenberg, Yinliang Yang, Steven H L Verhelst, Stephan A Sieber
Target profiling of 4-hydroxyderricin in S. aureus reveals seryl-tRNA synthetase binding and inhibition by covalent modification.
Mol Biosyst: 2013, 9(3);343-51
[PubMed:23295910] [WorldCat.org] [DOI] (I p)