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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS08190 [old locus tag: SACOL1606 ]
  • pan locus tag?: SAUPAN004129000
  • symbol: SACOL_RS08190
  • pan gene symbol?: —
  • synonym:
  • product: rhomboid family intramembrane serine protease

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL_RS08190 [old locus tag: SACOL1606 ]
  • symbol: SACOL_RS08190
  • product: rhomboid family intramembrane serine protease
  • replicon: chromosome
  • strand: -
  • coordinates: 1636419..1637882
  • length: 1464
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002951 (1636419..1637882) NCBI
  • BioCyc: SACOL_RS08190 BioCyc
  • MicrobesOnline: see SACOL1606

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    ATGAACATAGACAAACAATTTTGGAAAACAATATATTATTGGATTAGGTACTTGAATTTT
    GATATTGTCAGTAGGGAAAAAGATGACCAAGAAATTTGGTTAGCCCATAAAAGAAAAAAA
    CAAGTAGTCATTTTTAAACAACATATCAAGTCTACCCAAGAAATACGTTTTGACAAAGCG
    AAAGTGCTTGAACACAAAGATGAAATAGCAAATTTTATTTCTTTCGAACCACAAAGTTTT
    GAATTTTATTATTTTACAGAATCGGAATTTTCAGAAGAACAATTAAATGAAGTTTCGCCA
    ATTAGAATTAAATTCAATGTTATAAGACACACAAAAGATTTGATAAAGCATATGCCGAAT
    ATATTTTTGGCTAGACTTATTTCAGAAGATAATGATAAAAAGACATATATGTTCTATAAA
    CGCAAAGTATTAACCGATAACTTTTTAGATAAATATATGCAGAAATTTTCACCGGCAACA
    TACACAATAATATTTGTAAATGTCTTAATATGGTTATGTATGATTTTATATTTAAATAAT
    TTTTCGGATGTAAAATTATTAGATGTTGGCGGGTTAGTGCATTTTAATGTCGTACATGGT
    GAATGGTATCGAATTGTTACATCGATGTTTTTACATTTTAGTTTTGAACATATACTTATG
    AATATGCTTTCATTATTTATTTTTGGTAAAATAGTCGAAGCAATTATTGGTTCATGGCGG
    ATGTTAACTGTATACTTTATTGCAGGGTTGTTTGGAAACTTTGTATCACTATCATTTAAT
    ACGACTACAATTTCAGTTGGGGCTAGTGGTGCTATATTTGGTCTGATTGGATCAATTTTT
    GCGATGATGTATGTTTCAAAAACATTTAACAAAAAAATGTTAGGACAGTTATTAATTGCA
    TTAGTGATATTAGTTGGTGTTTCTCTGTTTATGTCAAATATAAATATTGTGGCGCATATT
    GGAGGATTCATTGGTGGTTTATTAATAACTTTAATTGGCTATTACTATAAAGTGAATCGT
    AATATTTTTTGGATTTTACTAATTGGTATGCTTGTTATATTTATTGCACTTCAAATTAGA
    ATTTTTACAATTAAAGAAGATAATATTTATAATAAATTGATCAAAGATGATATGACTAGT
    GGTAATTATGATAATGCTCAAAATATTGTGAAGCAGACAATAAATAAAAATTATGCCGAT
    GATCAAACATATTATTTAAGTGGTATGATTATGGCTACTATCAATTCTAAGTCCGAAGGT
    ATGACAGAATGGGAGCGAGGACTTAGAATGTTTCCTAAATCAGGTTTATTAAATTTTGAG
    TTAGCGATAGCAAATCGTTCATTAAATGATGATGAAAAAGCATTAAAATATGTGCGTAAA
    GCATTAAATGCAGACCCTAAAAATACAGATTATATTAACTTAGAAAAAGAGTTGACTAAA
    TCAAATGAGTCGAAAAATAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1464

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL_RS08190 [old locus tag: SACOL1606 ]
  • symbol: SACOL_RS08190
  • description: rhomboid family intramembrane serine protease
  • length: 487
  • theoretical pI: 9.54533
  • theoretical MW: 56889.1
  • GRAVY: 0.0568788

⊟Function[edit | edit source]

  • TIGRFAM:
    rhomboid family protease GlpG (TIGR04239; EC 3.4.21.105; HMM-score: 54.7)
    and 3 more
    rhombosortase (TIGR03902; EC 3.4.21.-; HMM-score: 42.9)
    putative PEP-CTERM system TPR-repeat lipoprotein (TIGR02917; HMM-score: 20.7)
    type IV pilus biogenesis/stability protein PilW (TIGR02521; HMM-score: 17.2)
  • TheSEED: see SACOL1606
  • PFAM:
    Rhomboid-like (CL0207) Rhomboid; Rhomboid family (PF01694; HMM-score: 124.4)
    and 12 more
    TPR (CL0020) Fis1_TPR_C; Fis1 C-terminal tetratricopeptide repeat (PF14853; HMM-score: 21.7)
    TPR_2; Tetratricopeptide repeat (PF07719; HMM-score: 19.9)
    TPR_16; Tetratricopeptide repeat (PF13432; HMM-score: 19.8)
    TPR_14; Tetratricopeptide repeat (PF13428; HMM-score: 19.6)
    TPR_8; Tetratricopeptide repeat (PF13181; HMM-score: 18)
    TPR_19; Tetratricopeptide repeat (PF14559; HMM-score: 16)
    TPR_CcmH_CycH; Cytochrome c-type biogenesis protein H TPR domain (PF23914; HMM-score: 14.8)
    TPR_1; Tetratricopeptide repeat (PF00515; HMM-score: 13.7)
    RNase_H (CL0219) DDE_Tnp_1; Transposase DDE domain (PF01609; HMM-score: 12.3)
    TPR (CL0020) TPR_17; Tetratricopeptide repeat (PF13431; HMM-score: 11.9)
    TPR_12; Tetratricopeptide repeat (PF13424; HMM-score: 11.7)
    no clan defined Sensor_TM1; Sensor N-terminal transmembrane domain (PF13755; HMM-score: 11.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 7
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0003
    • Cytoplasmic Membrane Score: 0.9891
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.0105
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001751
    • TAT(Tat/SPI): 0.000133
    • LIPO(Sec/SPII): 0.000329
  • predicted transmembrane helices (TMHMM): 7

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MNIDKQFWKTIYYWIRYLNFDIVSREKDDQEIWLAHKRKKQVVIFKQHIKSTQEIRFDKAKVLEHKDEIANFISFEPQSFEFYYFTESEFSEEQLNEVSPIRIKFNVIRHTKDLIKHMPNIFLARLISEDNDKKTYMFYKRKVLTDNFLDKYMQKFSPATYTIIFVNVLIWLCMILYLNNFSDVKLLDVGGLVHFNVVHGEWYRIVTSMFLHFSFEHILMNMLSLFIFGKIVEAIIGSWRMLTVYFIAGLFGNFVSLSFNTTTISVGASGAIFGLIGSIFAMMYVSKTFNKKMLGQLLIALVILVGVSLFMSNINIVAHIGGFIGGLLITLIGYYYKVNRNIFWILLIGMLVIFIALQIRIFTIKEDNIYNKLIKDDMTSGNYDNAQNIVKQTINKNYADDQTYYLSGMIMATINSKSEGMTEWERGLRMFPKSGLLNFELAIANRSLNDDEKALKYVRKALNADPKNTDYINLEKELTKSNESKNK

⊟Experimental data[edit | edit source]

  • experimentally validated: see SACOL1606
  • protein localization: see SACOL1606
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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