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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS07970 [old locus tag: SACOL1565 ]
  • pan locus tag?: SAUPAN004075000
  • symbol: SACOL_RS07970
  • pan gene symbol?: argR
  • synonym:
  • product: arginine repressor

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SACOL_RS07970 [old locus tag: SACOL1565 ]
  • symbol: SACOL_RS07970
  • product: arginine repressor
  • replicon: chromosome
  • strand: -
  • coordinates: 1601801..1602253
  • length: 453
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Location: NC_002951 (1601801..1602253) NCBI
  • BioCyc: SACOL_RS07970 BioCyc
  • MicrobesOnline: see SACOL1565

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    GTGCCCAAAAAATCGGTTAGGCATATAAAAATTAGAGAAATTATTTCAAATGAACAGATA
    GAGACACAAGATGAATTAGTTAAACGATTAAACGATTATGATTTAAATGTCACTCAAGCA
    ACTGTTTCTCGTGATATTAAAGAACTACAACTTATTAAAGTACCTATACCTTCAGGTCAA
    TATGTTTATAGTTTACCAAATGATAGAAAATTCCATCCTTTAGAAAAATTGGGACGTTAT
    TTAATGGATTCCTTTGTTAATATAGATGGTACTGATAATTTACTTGTTCTAAAAACATTA
    CCTGGTAATGCACAATCTATTGGAGCTATATTAGACCAAATCAATTGGGAAGAAGTACTA
    GGCACAATTTGTGGTGATGATACTTGTTTAATTATTTGTCGAAGCAAAGAGGCAAGTGAT
    GAAATCAAGTCAAGAATTTTCAATTTGTTATAA
    60
    120
    180
    240
    300
    360
    420
    453

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SACOL_RS07970 [old locus tag: SACOL1565 ]
  • symbol: SACOL_RS07970
  • description: arginine repressor
  • length: 150
  • theoretical pI: 5.28159
  • theoretical MW: 17097.6
  • GRAVY: -0.267333

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Amino acid biosynthesis Glutamate family arginine repressor (TIGR01529; HMM-score: 169.8)
    Signal transduction Regulatory functions DNA interactions arginine repressor (TIGR01529; HMM-score: 169.8)
  • TheSEED: see SACOL1565
  • PFAM:
    HTH (CL0123) Arg_repressor; Arginine repressor, DNA binding domain (PF01316; HMM-score: 94.5)
    no clan defined Arg_repressor_C; Arginine repressor, C-terminal domain (PF02863; HMM-score: 92.4)
    and 1 more
    HTH (CL0123) HTH_11; HTH domain (PF08279; HMM-score: 17)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • genes regulated by ArgR, TF important in Arginine biosynthesis, Arginine degradation: see SACOL1565

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003318
    • TAT(Tat/SPI): 0.000875
    • LIPO(Sec/SPII): 0.000397
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MPKKSVRHIKIREIISNEQIETQDELVKRLNDYDLNVTQATVSRDIKELQLIKVPIPSGQYVYSLPNDRKFHPLEKLGRYLMDSFVNIDGTDNLLVLKTLPGNAQSIGAILDQINWEEVLGTICGDDTCLIICRSKEASDEIKSRIFNLL

Experimental data[edit | edit source]

  • experimentally validated: see SACOL1565
  • protein localization: see SACOL1565
  • quantitative data / protein copy number per cell: see SACOL1565
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]