Jump to navigation
Jump to search
NCBI: 10-JUN-2013
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus COL
- locus tag: SACOL2682 [new locus tag: SACOL_RS14040 ]
- pan locus tag?: SAUPAN006404000
- symbol: SACOL2682
- pan gene symbol?: —
- synonym:
- product: hypothetical protein
⊟Additional information (user-provided)[edit | edit source]
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SACOL2682 [new locus tag: SACOL_RS14040 ]
- symbol: SACOL2682
- product: hypothetical protein
- replicon: chromosome
- strand: -
- coordinates: 2757708..2758319
- length: 612
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID: 3237011 NCBI
- RefSeq: YP_187469 NCBI
- BioCyc: see SACOL_RS14040
- MicrobesOnline: 914148 MicrobesOnline
⊟Phenotype[edit | edit source]
⊟Additional information (user-provided)[edit | edit source]
⊟DNA sequence[edit | edit source]
- 1
61
121
181
241
301
361
421
481
541
601ATGTATACGTTTGATGCACAATCATTAACTGCTAGAGAAAACTATAAATTATTAATTGGT
TCAATTATTCCACGACCTATAGCTTTTGTTACAACATTAAATCAAGATGCATCAGTAAAT
GCAGCACCATTTAGCTTTTTTAATATTGTTAATAATCATCCGCCAATGATTGCTATTGCA
GTTCAACGTGCAGGAGGTAAGAGAAAAGATACTGCATTAAATATAGAACGGACTGGAGAC
TTTGTTGTGCATATTACAGACGAAGATAATGTTCAAGATATTAATGAGACTGCAGCGCCG
TTAGCATATGGTGACAGTGAGTTGAGTCGTACAGAATTATCACTTTTAACATCTACAACG
ATTAAGACGCCAGGAATTAAAGATGCGAAAATGAGATTCGAATGTAAACTATCGCAAATG
ATATTGCTTGGAGATGTATTAGATGGGGCTGATTTAATAATAGGTGAAATTGTAACTTAT
CATATTGATGACAGTATTTATGAGGGTGATTTTAAAATCAATCCACACGCATTACAGGCT
GTTTCTCGTTTAGCCGGAAATGATTATGCTAAATTAGGGGGAATATTTACGATAAAGAGA
CCAGAAAAATAA60
120
180
240
300
360
420
480
540
600
612
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SACOL2682 [new locus tag: SACOL_RS14040 ]
- symbol: SACOL2682
- description: hypothetical protein
- length: 203
- theoretical pI: 5.04227
- theoretical MW: 22315.3
- GRAVY: -0.0935961
⊟Function[edit | edit source]
- TIGRFAM:
- TheSEED :
- FIG01108172: hypothetical protein
- PFAM: FMN-binding (CL0336) Flavin_Reduct; Flavin reductase like domain (PF01613; HMM-score: 80.5)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: unknown (no significant prediction)
- Cytoplasmic Score: 2.5
- Cytoplasmic Membrane Score: 2.5
- Cellwall Score: 2.5
- Extracellular Score: 2.5
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.992
- Cytoplasmic Membrane Score: 0.0007
- Cell wall & surface Score: 0
- Extracellular Score: 0.0072
- LocateP: Intracellular
- Prediction by SwissProt Classification: Cytoplasmic
- Pathway Prediction: No pathway
- Intracellular possibility: 1
- Signal peptide possibility: -1
- N-terminally Anchored Score: -1
- Predicted Cleavage Site: No CleavageSite
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.19492
- TAT(Tat/SPI): 0.021099
- LIPO(Sec/SPII): 0.003431
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Additional information (user-provided)[edit | edit source]
⊟Protein sequence[edit | edit source]
- MYTFDAQSLTARENYKLLIGSIIPRPIAFVTTLNQDASVNAAPFSFFNIVNNHPPMIAIAVQRAGGKRKDTALNIERTGDFVVHITDEDNVQDINETAAPLAYGDSELSRTELSLLTSTTIKTPGIKDAKMRFECKLSQMILLGDVLDGADLIIGEIVTYHIDDSIYEGDFKINPHALQAVSRLAGNDYAKLGGIFTIKRPEK
⊟Experimental data[edit | edit source]
- experimentally validated: PeptideAtlas
- protein localization: Cytoplasmic [1] [2] [3]
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: no polycistronic organisation predicted
⊟Regulation[edit | edit source]
- regulator: SigB* (activation) regulon
SigB* (sigma factor) controlling a large regulon involved in stress/starvation response and adaptation; [4] other strains
⊟Additional information (user-provided)[edit | edit source]
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Additional information (user-provided)[edit | edit source]
⊟Other information (user-provided)[edit | edit source]
You can add further information about the gene and protein here. [edit]
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Dörte Becher, Kristina Hempel, Susanne Sievers, Daniela Zühlke, Jan Pané-Farré, Andreas Otto, Stephan Fuchs, Dirk Albrecht, Jörg Bernhardt, Susanne Engelmann, Uwe Völker, Jan Maarten van Dijl, Michael Hecker
A proteomic view of an important human pathogen--towards the quantification of the entire Staphylococcus aureus proteome.
PLoS One: 2009, 4(12);e8176
[PubMed:19997597] [WorldCat.org] [DOI] (I e) - ↑ Kristina Hempel, Florian-Alexander Herbst, Martin Moche, Michael Hecker, Dörte Becher
Quantitative proteomic view on secreted, cell surface-associated, and cytoplasmic proteins of the methicillin-resistant human pathogen Staphylococcus aureus under iron-limited conditions.
J Proteome Res: 2011, 10(4);1657-66
[PubMed:21323324] [WorldCat.org] [DOI] (I p) - ↑ Andreas Otto, Jan Maarten van Dijl, Michael Hecker, Dörte Becher
The Staphylococcus aureus proteome.
Int J Med Microbiol: 2014, 304(2);110-20
[PubMed:24439828] [WorldCat.org] [DOI] (I p) - ↑ Markus Bischoff, Paul Dunman, Jan Kormanec, Daphne Macapagal, Ellen Murphy, William Mounts, Brigitte Berger-Bächi, Steven Projan
Microarray-based analysis of the Staphylococcus aureus sigmaB regulon.
J Bacteriol: 2004, 186(13);4085-99
[PubMed:15205410] [WorldCat.org] [DOI] (P p)