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NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL2170 [new locus tag: SACOL_RS11410 ]
  • pan locus tag?: SAUPAN005571000
  • symbol: SACOL2170
  • pan gene symbol?: sfnaA
  • synonym:
  • product: transporter

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL2170 [new locus tag: SACOL_RS11410 ]
  • symbol: SACOL2170
  • product: transporter
  • replicon: chromosome
  • strand: -
  • coordinates: 2250059..2251252
  • length: 1194
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGACAAAATATTTTTTTAGCAGTTCTTTTCTACTATTTCTAGGTAATTGGATTGGACAA
    ATAGGGCTAAATTGGTTTGTACTTACCACTTATCATAACGCAGTTTATCTGGGGATTGTC
    AATTTTTGCAGACTTGTACCAATATTATTACTAAGTGTGTGGGCAGGGGCAATTGCCGAT
    AAATATGATAAAGGGCGATTGCTGAGAATTACAATTTCATCATCATTTTTAGTAACTGCA
    ATTTTATGTGTGCTCACGTATAGTTTCACTGCAATTCCAATTAGCGTCATTATTATATAT
    GCGACATTAAGAGGGATTTTAAGTGCGGTTGAAACACCTTTAAGACAAGCAATCTTACCA
    GATTTATCAGATAAAATATCTACTACACAAGCTGTATCATTTCATTCATTCATCATTAAT
    ATTTGTCGTTCAATAGGGCCTGCCATTGCTGGTGTCATATTAGCAGTCTATCATGCGCCA
    ACAACATTTCTTGCACAGGCAATTTGTTATTTTATCGCAGTTTTATTATGCTTACCATTA
    CATTTTAAAGTAACTAAAATACCTGAAGATGCATCAAGATACATGCCGTTAAAAGTTATT
    ATAGATTACTTCAAATTACATATGGAAGGTCGACAAATATTTATAACATCATTATTGATT
    ATGGCGACAGGTTTTTCATATACGACACTTTTACCAGTTTTGACAAACAAAGTATTTCCG
    GGGAAATCTGAAATATTTGGTATCGCTATGACGATGTGTGCCATTGGTGGTATTATTGCA
    ACGCTAGTTTTACCTAAAGTACTTAAATATATTGGTATGGTAAATATGTATTATTTAAGT
    TCATTTTTATTTGGCATTGCTTTGTTAGGTGTGGTATTTCACAATATTGTCATCATGTTC
    ATTTGTATTACATTGATTGGGTTATTTAGTCAATGGGCACGTACGACAAATCGCGTTTAT
    TTTCAAAATAATGTTAAAGATTATGAACGTGGTAAAGTACTGAGTATTATTATGATGGAT
    AGAGGTATGATTCCATTGGGAAGTCTATTAATGAGTATATGTGCAGATGTGTTTGGCATT
    GTTAGAACTTTTTCAATAATGGGAATAAGTACTATATGCATTACAATGGTATTCTATTTT
    ATAAATAGAAAGTTGAAGTTAAAGTTGGAGGAAAGTAATCATGGTATATCTTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1194

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL2170 [new locus tag: SACOL_RS11410 ]
  • symbol: SACOL2170
  • description: transporter
  • length: 397
  • theoretical pI: 9.65741
  • theoretical MW: 44337.1
  • GRAVY: 0.86801

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Cations and iron carrying compounds H+ Antiporter protein (TIGR00900; HMM-score: 123.6)
    and 1 more
    multidrug resistance protein (TIGR00880; HMM-score: 31.4)
  • TheSEED  :
    • Macrolide-efflux protein
  • PFAM:
    MFS (CL0015) MFS_3; Transmembrane secretion effector (PF05977; HMM-score: 141.6)
    and 2 more
    MFS_1; Major Facilitator Superfamily (PF07690; HMM-score: 100.5)
    MFS_2; MFS/sugar transport protein (PF13347; HMM-score: 13.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 12
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.009055
    • TAT(Tat/SPI): 0.00056
    • LIPO(Sec/SPII): 0.01214
  • predicted transmembrane helices (TMHMM): 11

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MTKYFFSSSFLLFLGNWIGQIGLNWFVLTTYHNAVYLGIVNFCRLVPILLLSVWAGAIADKYDKGRLLRITISSSFLVTAILCVLTYSFTAIPISVIIIYATLRGILSAVETPLRQAILPDLSDKISTTQAVSFHSFIINICRSIGPAIAGVILAVYHAPTTFLAQAICYFIAVLLCLPLHFKVTKIPEDASRYMPLKVIIDYFKLHMEGRQIFITSLLIMATGFSYTTLLPVLTNKVFPGKSEIFGIAMTMCAIGGIIATLVLPKVLKYIGMVNMYYLSSFLFGIALLGVVFHNIVIMFICITLIGLFSQWARTTNRVYFQNNVKDYERGKVLSIIMMDRGMIPLGSLLMSICADVFGIVRTFSIMGISTICITMVFYFINRKLKLKLEESNHGIS

⊟Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: Fur* (repression) regulon
    Fur*(TF)important in Iron homeostasis; RegPrecise 

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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