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NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL1712 [new locus tag: SACOL_RS08745 ]
  • pan locus tag?: SAUPAN004278000
  • symbol: SACOL1712
  • pan gene symbol?: —
  • synonym:
  • product: abrB protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL1712 [new locus tag: SACOL_RS08745 ]
  • symbol: SACOL1712
  • product: abrB protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1743452..1744525
  • length: 1074
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGGCAATGATATATAGAAATAATTTCATTGTGTTCGTTTTATCATTTTTTATTAGTATT
    CTACTGTATTCATCGCACGTATTACTTCCATTTATGTTTGGTCCTATTATCGCATCAATC
    ATTTGTGTAAAAGTTTTCAAACTTGATATTAAATGGCCATTCTTACTTAGTGAATTAGGT
    ATTGTACTATTAGGTGTGCAAATCGGATCAACGTTTACGAAAAATGTCGTTATGGATATT
    AAAAACAATTGGCTTTCGATTATTGTTGTATCTATTTCGATATTATTAATTGCAATAGTA
    ATGGCATTTGTTTTTAAAAAAATTGCACGTATTAATACAGAAACAGCTATTTTAAGTGTT
    ATACCAGGAGCACTAACACAAATGCTGGTCATGGCTGAACAAGACAAACGTGCTAATTTG
    TTAGTTGTTAGCTTAACGCAAACATCACGAATTATATTTGTTGTTGTTTTAGTACCGTTC
    ATTTCATATTTTTTTCATGATGGTAACATGCATGCGAATGGAAAGTTAACAAAAGTCTTG
    CCTTTATCACAAGTATTAAACATAGGGCAAATAGTTATTTTAGCGATAGCTATCTTTATA
    GTTTATCTAATTATGTCTAAAATAAAGTTTCCAACATTTCAATTATTAGCACCACTCATT
    GTATTAATTGTTTGGAATTTTTCTACAGGTTTAACATTTACACTAGATCATTGGTTGTTG
    AACATGGCACAACTAATATATATGATTAGAATTGGAGTTCAAATTGCGCATTTATTGTCA
    GATTTAAAAGGTAGACTAGCAATCGCAATTACAATTCAAAATATTATGTTGATAATTGGT
    GCGCTAATCATGGTTTATATCATACATTTCTTTGATAATAATCCTATTAATGAATTGTTT
    CTTGGTGCAGCACCAGGAGGGGTTAATCAGATAGTTTTAGTTGCATTAGCTACTGGTGCC
    GATGTTGCTATGATTACGAGTTATCATATTTTCCGAATCTTTTTCATCCTATTTATTATT
    GCACCAGGAATTAATTACTTTTTAAAATATCGTTCGAATAAGCGTGAAGATTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1074

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL1712 [new locus tag: SACOL_RS08745 ]
  • symbol: SACOL1712
  • description: abrB protein
  • length: 357
  • theoretical pI: 10.1975
  • theoretical MW: 40065.4
  • GRAVY: 1.08796

⊟Function[edit | edit source]

  • TIGRFAM:
    membrane protein AbrB duplication (TIGR03082; HMM-score: 238.7)
  • TheSEED  :
    • FIG01107906: hypothetical protein
  • PFAM:
    Membrane_trans (CL0142) AbrB; Transition state regulatory protein AbrB (PF05145; HMM-score: 263.1)
    and 1 more
    CPA_AT (CL0064) Asp-Al_Ex; Predicted Permease Membrane Region (PF06826; HMM-score: 22.9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 9
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.9999
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0001
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006528
    • TAT(Tat/SPI): 0.000621
    • LIPO(Sec/SPII): 0.005898
  • predicted transmembrane helices (TMHMM): 10

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MAMIYRNNFIVFVLSFFISILLYSSHVLLPFMFGPIIASIICVKVFKLDIKWPFLLSELGIVLLGVQIGSTFTKNVVMDIKNNWLSIIVVSISILLIAIVMAFVFKKIARINTETAILSVIPGALTQMLVMAEQDKRANLLVVSLTQTSRIIFVVVLVPFISYFFHDGNMHANGKLTKVLPLSQVLNIGQIVILAIAIFIVYLIMSKIKFPTFQLLAPLIVLIVWNFSTGLTFTLDHWLLNMAQLIYMIRIGVQIAHLLSDLKGRLAIAITIQNIMLIIGALIMVYIIHFFDNNPINELFLGAAPGGVNQIVLVALATGADVAMITSYHIFRIFFILFIIAPGINYFLKYRSNKRED

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: Integral membrane [1]
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • data available for JSNZ

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Andreas Otto, Jan Maarten van Dijl, Michael Hecker, Dörte Becher
    The Staphylococcus aureus proteome.
    Int J Med Microbiol: 2014, 304(2);110-20
    [PubMed:24439828] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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