Jump to navigation
Jump to search
NCBI: 10-JUN-2013
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus COL
- locus tag: SACOL1629 [new locus tag: SACOL_RS08305 ]
- pan locus tag?: SAUPAN004155000
- symbol: SACOL1629
- pan gene symbol?: —
- synonym:
- product: hypothetical protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SACOL1629 [new locus tag: SACOL_RS08305 ]
- symbol: SACOL1629
- product: hypothetical protein
- replicon: chromosome
- strand: -
- coordinates: 1659132..1659830
- length: 699
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID: 3238276 NCBI
- RefSeq: YP_186469 NCBI
- BioCyc: see SACOL_RS08305
- MicrobesOnline: 913078 MicrobesOnline
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
61
121
181
241
301
361
421
481
541
601
661ATGAGTGTCGGTATTCTAATTTTTGTCATATCAGTGATCATTTCTATCATTACTACTATG
CGCGAAAATAGTCATAAAGATAGACAAAATCAAAAGCCACCTCAAAAAACATCTACCGAT
AATGAACCAAAAAAAGGTGGCTTTTTTGAAGAAATTGAGCGAACGTTTAAAGAAATAAGT
GAAGAATTAAATGAAGAAGAAAAGAAATCATCGAAACGAAAATATGATGATACGTTACCA
CCTTTATTCGATGAACTTCCAAAGGAAGAGCCTAAATCGAAACCTGTTGTAGAACCTATG
GCACCTAAAAAACAACAAGAAACAAAACCGATGACAGAGAAACCAATCACAGTGCCTAAA
GCAGAACCGGTGGAGCAGAAACATAGACCTTCTAGACAAGATAATTCTGACGAAATTAGA
CGTCAATTAGAAAAATCACTTAGAGATGATATTAAAACGATTCGTACTGACATTGATAGA
GAAAAAGAAAAGCAAATTGCTAAAATGGAAAAACGTGCTAGAGATATTATTGAGGATAAA
TACTTATCTGAACGTACAAAACGTTTGAAATTAAAGCAGCTGCTTAATTCTCAAAATGTC
GAAAAAGATTTGACTAAATCAGCGTTCCAATTTGATAAAGATGAAGTAATCAATGGTATG
ATATGGTCAGAAATTTTAGCTAAACCAAAACAATTATAA60
120
180
240
300
360
420
480
540
600
660
699
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SACOL1629 [new locus tag: SACOL_RS08305 ]
- symbol: SACOL1629
- description: hypothetical protein
- length: 232
- theoretical pI: 9.69683
- theoretical MW: 27256
- GRAVY: -1.13578
⊟Function[edit | edit source]
- TIGRFAM: Cellular processes Pathogenesis putative immunoglobulin-blocking virulence protein (TIGR04526; HMM-score: 17.2)and 2 moreEnergy metabolism TCA cycle succinate dehydrogenase, flavoprotein subunit (TIGR01816; HMM-score: 11)RNA polymerase sigma factor, sigma-70 family (TIGR02937; HMM-score: 4.6)
- TheSEED :
- Uncharacterized membrane anchored protein YqfB
- PFAM: no clan defined EphA2_TM; Ephrin type-A receptor 2 transmembrane domain (PF14575; HMM-score: 15.4)PulG; Type II secretory pathway pseudopilin (PF11773; HMM-score: 12.8)and 4 moreDUF2897; Protein of unknown function (DUF2897) (PF11446; HMM-score: 11.6)IncA; IncA protein (PF04156; HMM-score: 10.2)SICA_like (CL0474) SICA_alpha; SICA extracellular alpha domain (PF12887; HMM-score: 7.7)no clan defined Ndc1_Nup; Nucleoporin protein Ndc1-Nup (PF09531; HMM-score: 5.4)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helix: 1
- LocateP: N-terminally anchored (No CS)
- Prediction by SwissProt Classification: Membrane
- Pathway Prediction: Sec-(SPI)
- Intracellular possibility: 0.5
- Signal peptide possibility: 0
- N-terminally Anchored Score: 4
- Predicted Cleavage Site: No CleavageSite
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.351133
- TAT(Tat/SPI): 0.001289
- LIPO(Sec/SPII): 0.216154
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MSVGILIFVISVIISIITTMRENSHKDRQNQKPPQKTSTDNEPKKGGFFEEIERTFKEISEELNEEEKKSSKRKYDDTLPPLFDELPKEEPKSKPVVEPMAPKKQQETKPMTEKPITVPKAEPVEQKHRPSRQDNSDEIRRQLEKSLRDDIKTIRTDIDREKEKQIAKMEKRARDIIEDKYLSERTKRLKLKQLLNSQNVEKDLTKSAFQFDKDEVINGMIWSEILAKPKQL
⊟Experimental data[edit | edit source]
- experimentally validated: PeptideAtlas
- protein localization: Signal peptide containing [1] [2] [3]
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Dörte Becher, Kristina Hempel, Susanne Sievers, Daniela Zühlke, Jan Pané-Farré, Andreas Otto, Stephan Fuchs, Dirk Albrecht, Jörg Bernhardt, Susanne Engelmann, Uwe Völker, Jan Maarten van Dijl, Michael Hecker
A proteomic view of an important human pathogen--towards the quantification of the entire Staphylococcus aureus proteome.
PLoS One: 2009, 4(12);e8176
[PubMed:19997597] [WorldCat.org] [DOI] (I e) - ↑ Kristina Hempel, Florian-Alexander Herbst, Martin Moche, Michael Hecker, Dörte Becher
Quantitative proteomic view on secreted, cell surface-associated, and cytoplasmic proteins of the methicillin-resistant human pathogen Staphylococcus aureus under iron-limited conditions.
J Proteome Res: 2011, 10(4);1657-66
[PubMed:21323324] [WorldCat.org] [DOI] (I p) - ↑ Andreas Otto, Jan Maarten van Dijl, Michael Hecker, Dörte Becher
The Staphylococcus aureus proteome.
Int J Med Microbiol: 2014, 304(2);110-20
[PubMed:24439828] [WorldCat.org] [DOI] (I p)