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NCBI: 26-AUG-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA1388 [new locus tag: SA_RS07850 ]
  • pan locus tag?: SAUPAN004140000
  • symbol: SA1388
  • pan gene symbol?: —
  • synonym:
  • product: hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA1388 [new locus tag: SA_RS07850 ]
  • symbol: SA1388
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1593470..1594570
  • length: 1101
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    ATGAAAATAGCTGATTTAATGACATTGTTAGATCATCATGTGCCATTTAGTACTGCTGAA
    TCTTGGGATAATGTAGGATTGTTAATAGGTGATGGAGATGTTGAAGTTACTGGTGTTTTA
    ACAGCATTAGACTGTACGTTGGAAGTAGTAAATGAAGCAATCGAAAAAGGTTATAATACT
    ATTATTAGTCATCATCCTCTAATCTTTAAAGGCGTAACATCATTAAAAGCTAATGGTTAT
    GGTTTGATCATTAGAAAACTAATTCAACATGACATTAATTTAATAGCGATGCATACAAAT
    TTAGATGTAAATCCGTATGGTGTCAATATGATGTTGGCGAAGGCGATGGGTTTGAAGAAC
    ATTTCAATAATAAATAATCAACAAGATGTATACTATAAAGTTCAAACATATATACCTAAG
    GATAATGTTGGACCATTTAAAGATAAGCTTAGTGAAAATGGATTAGCGCAAGAAGGTAAT
    TATGAATATTGTTTCTTTGAAAGTGAAGGAAGAGGGCAATTCAAACCAGTTGGTGAAGCT
    AATCCAACAATAGGACAAATTGATAAAATTGAAGATGTAGATGAAGTTAAAATTGAATTT
    ATGATAGATGCATATCAAAAGTCAAGGGCTGAGCAATTAATTAAACAATACCATCCATAT
    GAAACACCGGTATTTGATTTTATTGAGATAAAACAAACATCCCTTTATGGACTTGGCGTT
    ATGGCAGAAGTGGATAATCAAATGACATTGGAAGATTTCGCAGCTGATATTAAATCTAAA
    TTAAATATCCCAAGTGTCCGTTTTGTTGGTGAGTCTAATCAGAAAATTAAACGTATTGCA
    ATTATTGGTGGTTCAGGTATTGGATATGAATATCAAGCTGTCCAACAAGGCGCAGATGTC
    TTTGTTACAGGTGATATTAAACATCATGATGCCTTAGATGCTAAAATTCATGGTGTGAAT
    TTAATTGATATTAATCATTACAGCGAATATGTGATGAAAGAAGGTTTAAAAACGTTACTA
    ATGAATTGGTTCAATATAGAAAAAATAAATATAGATGTTGAAGCATCTACAATTAATACA
    GATCCATTTCAATATATTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1101

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA1388 [new locus tag: SA_RS07850 ]
  • symbol: SA1388
  • description: hypothetical protein
  • length: 366
  • theoretical pI: 4.66964
  • theoretical MW: 41074.6
  • GRAVY: -0.162568

⊟Function[edit | edit source]

  • TIGRFAM:
    Unknown function General dinuclear metal center protein, YbgI/SA1388 family (TIGR00486; HMM-score: 234)
  • TheSEED  :
    • Bsu YqfO NIF3/CutA domain
    • Nif3-like dinuclear metal center hexameric protein
    EC699-706  FIG137478: Hypothetical protein YbgI
  • PFAM:
    no clan defined NIF3; NIF3 (NGG1p interacting factor 3) (PF01784; HMM-score: 270.6)
    and 1 more
    GlnB-like (CL0089) CutA1; CutA1 divalent ion tolerance protein (PF03091; HMM-score: 15.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.018413
    • TAT(Tat/SPI): 0.00036
    • LIPO(Sec/SPII): 0.000928
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKIADLMTLLDHHVPFSTAESWDNVGLLIGDGDVEVTGVLTALDCTLEVVNEAIEKGYNTIISHHPLIFKGVTSLKANGYGLIIRKLIQHDINLIAMHTNLDVNPYGVNMMLAKAMGLKNISIINNQQDVYYKVQTYIPKDNVGPFKDKLSENGLAQEGNYEYCFFESEGRGQFKPVGEANPTIGQIDKIEDVDEVKIEFMIDAYQKSRAEQLIKQYHPYETPVFDFIEIKQTSLYGLGVMAEVDNQMTLEDFAADIKSKLNIPSVRFVGESNQKIKRIAIIGGSGIGYEYQAVQQGADVFVTGDIKHHDALDAKIHGVNLIDINHYSEYVMKEGLKTLLMNWFNIEKINIDVEASTINTDPFQYI

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Kumar Singh Saikatendu, Xuejun Zhang, Lisa Kinch, Matthew Leybourne, Nick V Grishin, Hong Zhang
Structure of a conserved hypothetical protein SA1388 from S. aureus reveals a capped hexameric toroid with two PII domain lids and a dinuclear metal center.
BMC Struct Biol: 2006, 6;27
[PubMed:17187687] [WorldCat.org] [DOI] (I e)

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