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NCBI: 26-AUG-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA1096 [new locus tag: SA_RS06205 ]
  • pan locus tag?: SAUPAN003551000
  • symbol: clpQ
  • pan gene symbol?: hslV
  • synonym:
  • product: ATP-dependent protease peptidase subunit

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA1096 [new locus tag: SA_RS06205 ]
  • symbol: clpQ
  • product: ATP-dependent protease peptidase subunit
  • replicon: chromosome
  • strand: +
  • coordinates: 1242040..1242585
  • length: 546
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGAGTAATACAACATTACATGCAACAACAATTTATGCTGTAAGACATAATGGGAAAGCA
    GCTATGGCTGGAGATGGACAAGTAACGCTTGGTCAACAAGTCATCATGAAACAAACGGCA
    AGAAAAGTGCGACGTTTATATGAAGGTAAAGTGTTAGCTGGTTTCGCAGGTAGTGTAGCA
    GATGCGTTTACGTTATTTGAAAAATTTGAAACAAAATTACAACAGTTTAGTGGTAACTTA
    GAAAGAGCTGCTGTTGAATTGGCACAAGAATGGCGAGGCGATAAACAATTACGTCAATTA
    GAAGCTATGCTAATTGTAATGGATAAAGATGCTATTTTAGTTGTCAGTGGAACTGGCGAA
    GTTATTGCCCCAGATGATGACCTTATCGCTATTGGATCAGGGGGCAACTACGCATTAAGC
    GCAGGACGTGCATTGAAACGCCATGCATCGCATTTGTCTGCTGAAGAAATGGCATATGAG
    AGCTTGAAAGTAGCGGCTGATATTTGTGTCTTTACCAACGATAATATTGTTGTTGAAACA
    CTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    546

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA1096 [new locus tag: SA_RS06205 ]
  • symbol: ClpQ
  • description: ATP-dependent protease peptidase subunit
  • length: 181
  • theoretical pI: 6.11631
  • theoretical MW: 19572.2
  • GRAVY: -0.0154696

⊟Function[edit | edit source]

  • reaction:
    EC 3.4.25.2?  ExPASy
    HslU--HslV peptidase ATP-dependent cleavage of peptide bonds with broad specificity
  • TIGRFAM:
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides ATP-dependent protease HslVU, peptidase subunit (TIGR03692; EC 3.4.25.2; HMM-score: 276.6)
    and 2 more
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides proteasome endopeptidase complex, archaeal, beta subunit (TIGR03634; EC 3.4.25.1; HMM-score: 29.2)
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides proteasome, beta subunit (TIGR03690; EC 3.4.25.1; HMM-score: 25.9)
  • TheSEED  :
    • ATP-dependent protease subunit HslV (EC 3.4.25.2)
    Protein Metabolism Protein degradation Proteasome bacterial  ATP-dependent protease HslV (EC 3.4.25.-)
    and 1 more
    Protein Metabolism Protein degradation Proteolysis in bacteria, ATP-dependent  ATP-dependent protease HslV (EC 3.4.25.-)
  • PFAM:
    NTN (CL0052) Proteasome; Proteasome subunit (PF00227; HMM-score: 95.7)
    and 1 more
    NADP_Rossmann (CL0063) Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase (PF07992; HMM-score: 15.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.011612
    • TAT(Tat/SPI): 0.001933
    • LIPO(Sec/SPII): 0.00229
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSNTTLHATTIYAVRHNGKAAMAGDGQVTLGQQVIMKQTARKVRRLYEGKVLAGFAGSVADAFTLFEKFETKLQQFSGNLERAAVELAQEWRGDKQLRQLEAMLIVMDKDAILVVSGTGEVIAPDDDLIAIGSGGNYALSAGRALKRHASHLSAEEMAYESLKVAADICVFTNDNIVVETL

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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