PangenomeCOLN315NCTC8325NewmanUSA300_FPR3757JSNZ04-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 26-AUG-2013

⊟Summary

• organism: Staphylococcus aureus N315
• locus tag: SA0311 [new locus tag: SA_RS01790 ]
• pan locus tag^?: SAUPAN001852000
• symbol: SA0311
• pan gene symbol^?: —
• synonym:
• product: hypothetical protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SA0311 [new locus tag: SA_RS01790 ]
• symbol: SA0311
• product: hypothetical protein
• replicon: chromosome
• strand: -
• coordinates: 368675..369874
• length: 1200
• essential: no DEG other strains

⊟Accession numbers

• Gene ID: 1123090 NCBI
• RefSeq: NP_373557 NCBI
• BioCyc: see SA_RS01790
• MicrobesOnline: 102583 MicrobesOnline

⊟Phenotype

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⊟DNA sequence

• 1
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  121
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  1141
  
  ATGTACCGATACAAACCACTTTTACAATCAATCCACTTACCTAATGGCATCAAAATTTCG
  AATCGCTTTGTATTATCACCAATGACCGTAAACGCATCAACAAAAGAAGGCTATATTACA
  AAAGCAGACTTGGCTTATGCTGCACGTCGCTCTAATTCAGCTGGAATGCAAGTCACCGGC
  GCTGCTTACATTGAACCTTATGGTAAATTGTTTGAATATGGCTTTAATATTGATCATGAT
  GCTTGTATCCCTGGATTAACTAACATGGCATCTACGATGAAACAACATGGTAGCCTCGCT
  ATTATCCAGCTAGCGCATGCTGGTCGTTTTTCAAATCAAGCCATTTTAAATTTTGGAAAG
  GTGTATGGACCAAGTCCTATGACTTTGCATTCACCGATTGAACACGTTGTTATCGCCATG
  TCTCATGAGAAAATCAATAGCATCATTCAGCAGTATCGCGATGCTACATTACGCGCGATT
  AAAGCAGGTTTTGATGGTGTGGAAATTTCGATTGCACAACGTTTGCTGATTCAAACATTT
  TTCTCAACTTTTTCAAATAGACGTACAGACCATTACGGTGCCGACTCATTAAAAAATCGT
  GCAAGATTATGTTTAGAAGTTATGCGTGCGGTACAAGAAGTGATTGATAAAGAAGCACCT
  GACAATTTTATTTTAGGATTTCGAGCAACGCCAGAAGAAACCAGAGGCAGTGATTTAGGA
  TATACCATTGACGAGTTCAACCAATTAATCGATTGGGTCATGGACGTTTCAAACATCCAA
  TACTTAGCAATCGCTAGCTGGGGTCGACATATTTATCAAAATACGTCTCGTACACCAGGT
  GATCATTTCGGTCGACCAGTTAACCAAATTGTCTATGAACATTTAGCAGGTCGTATCCCT
  TTAATTGCAAGTGGCGGGATTAATTCTCCAGAGTCTGCTTTAGATGCTTTACAACATGCA
  GATATGGTCGGCATGTCTTCGCCTTTTGTCACAGAACCTGACTTTGTGCATAAACTTGCT
  GAACAGCGACCACATGATATCAATCTTGAATTTTCTATGGCAGATTTAGAAGATTTAGCC
  ATTCCACATGCTGCTTTTAAAGATATTGTTAAAATGATGGATTATGGGGAAGGTCTAAAG
  AAGCATACCCGTGACGCTTTACGTCAATTGGAACAGAATTATCATGACTCATCGTCTTAA
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⊟Protein

⊟General

• locus tag: SA0311 [new locus tag: SA_RS01790 ]
• symbol: SA0311
• description: hypothetical protein
• length: 399
• theoretical pI: 6.76511
• theoretical MW: 44616.4
• GRAVY: -0.266165

⊟Function

• TIGRFAM:
  mycofactocin system FadH/OYE family oxidoreductase 2 (TIGR03997; EC 1.-.-.-; HMM-score: 148.8)
  and 3 more
  mycofactocin system FadH/OYE family oxidoreductase 1 (TIGR03996; EC 1.-.-.-; HMM-score: 100.7)
  3-isopropylmalate dehydratase, small subunit (TIGR02087; HMM-score: 13.3)
  Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Other isopentenyl-diphosphate delta-isomerase, type 2 (TIGR02151; EC 5.3.3.2; HMM-score: 11.6)
• TheSEED  :
  • Lipoylation-related NADH-dependent flavin oxidoreductase
• PFAM:
  TIM_barrel (CL0036) Oxidored_FMN; NADH:flavin oxidoreductase / NADH oxidase family (PF00724; HMM-score: 185.2)
  and 4 more
  DHO_dh; Dihydroorotate dehydrogenase (PF01180; HMM-score: 16.3)
  His_biosynth; Histidine biosynthesis protein (PF00977; HMM-score: 14.8)
  DHDPS; Dihydrodipicolinate synthetase family (PF00701; HMM-score: 12.8)
  Dus; Dihydrouridine synthase (Dus) (PF01207; HMM-score: 11.7)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• DeepLocPro: Cytoplasmic
  • Cytoplasmic Score: 0.9773
  • Cytoplasmic Membrane Score: 0.008
  • Cell wall & surface Score: 0.0005
  • Extracellular Score: 0.0142
• LocateP: Intracellular
  • Prediction by SwissProt Classification: Cytoplasmic
  • Pathway Prediction: No pathway
  • Intracellular possibility: 0.67
  • Signal peptide possibility: -0.5
  • N-terminally Anchored Score: -1
  • Predicted Cleavage Site: No CleavageSite
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.092574
  • TAT(Tat/SPI): 0.010706
  • LIPO(Sec/SPII): 0.005287
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 15926024 NCBI
• RefSeq: NP_373557 NCBI
• UniProt: A0A0H3JJQ2 UniProt

⊟Protein sequence

• MYRYKPLLQSIHLPNGIKISNRFVLSPMTVNASTKEGYITKADLAYAARRSNSAGMQVTGAAYIEPYGKLFEYGFNIDHDACIPGLTNMASTMKQHGSLAIIQLAHAGRFSNQAILNFGKVYGPSPMTLHSPIEHVVIAMSHEKINSIIQQYRDATLRAIKAGFDGVEISIAQRLLIQTFFSTFSNRRTDHYGADSLKNRARLCLEVMRAVQEVIDKEAPDNFILGFRATPEETRGSDLGYTIDEFNQLIDWVMDVSNIQYLAIASWGRHIYQNTSRTPGDHFGRPVNQIVYEHLAGRIPLIASGGINSPESALDALQHADMVGMSSPFVTEPDFVHKLAEQRPHDINLEFSMADLEDLAIPHAAFKDIVKMMDYGEGLKKHTRDALRQLEQNYHDSSS

⊟Experimental data

• experimentally validated: data available for NCTC8325
• protein localization: data available for COL
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

• MicrobesOnline: SA0310 < SA0311

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You can add further information about the gene and protein here. [edit]

⊟Literature

⊟References

⊟Relevant publications