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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS02280 [old locus tag: NWMN_0403 ]
  • pan locus tag?: SAUPAN002134000
  • symbol: NWMN_RS02280
  • pan gene symbol?: lpl1
  • synonym:
  • product: tandem-type lipoprotein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_RS02280 [old locus tag: NWMN_0403 ]
  • symbol: NWMN_RS02280
  • product: tandem-type lipoprotein
  • replicon: chromosome
  • strand: +
  • coordinates: 453221..453994
  • length: 774
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Location: NC_009641 (453221..453994) NCBI
  • BioCyc:
  • MicrobesOnline: see NWMN_0403

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
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    481
    541
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    661
    721
    ATGGGATATTTAAAAAGGTTTGCATTGTACATAAGCGTTATGATTTTAATATTTGCGATA
    GCAGGTTGTGGCAAAGGTAATGAAACAAAAGAAGATTCAAAGGAAGAACAAATCAAAAAG
    AGCTTTGCGAAAACATTAGATATGTATCCAATTAAGAATCTCGAGGACTTATATGACAAA
    GAAGGATATCGAGATAGCGAATTTAAAAAAGGTGACAAAGGGATGTGGACGATATATACA
    GATTTCGCCAAAAGTAATAAACCGGGTGAATTGGATGATGAAGGTATGGTTTTAAATCTG
    GATAGGAATACTAGAACCGCTAAAGGCCATTATTTTGTTACTACATTTTACCGGAATGGT
    AAACTACCAGATGAAAAGAATTATAAAATTGAAATGAAAAATAATAAGATTATTTTATTA
    GATGAAGTAAAAGATGATAAGCTCAAGCAGAAAATAGAAAACTTTAAATTTTTCGGTCAA
    TATGCAAATCTTAAAGAATTGAGAAAATATAATAATGGTGATGTTTCAATTAATGAAAAT
    GTTCCTAGTTATGATGTTGAATACAAAATGAGCAATAAAGATGAAATAGTTAAGGAATTA
    AGAAGTCGTTATAATATTTCGACTGAAAAATCACCTATATTAAAAATGCATATTGATGGG
    GACCTGAAAGGCAGTTCTGTAGGTTATAGAAAGTTAGAAATTGACTTTTCAAAACGTGAA
    AACAGCAAATTATCAGTCATTGAATTTTTAAGTTATAAACCAGCGAAAAAATAG
    60
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    774

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: NWMN_RS02280 [old locus tag: NWMN_0403 ]
  • symbol: NWMN_RS02280
  • description: tandem-type lipoprotein
  • length: 257
  • theoretical pI: 9.51151
  • theoretical MW: 30008.1
  • GRAVY: -0.829183

Function[edit | edit source]

  • TIGRFAM:
    Staphylococcus tandem lipoproteins (TIGR01742; HMM-score: 380.9)
  • TheSEED: data available for N315, USA300_FPR3757
  • PFAM:
    LolA_LolB (CL0048) DUF576; Csa1 family (PF04507; HMM-score: 358.2)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helix: 1
  • LocateP:
  • SignalP: Signal peptide LIPO(Sec/SPII) length 22 aa
    • SP(Sec/SPI): 0.000482
    • TAT(Tat/SPI): 0.000056
    • LIPO(Sec/SPII): 0.999267
    • Cleavage Site: CS pos: 22-23. IAG-CG. Pr: 0.9997
  • predicted transmembrane helices (TMHMM): 1

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MGYLKRFALYISVMILIFAIAGCGKGNETKEDSKEEQIKKSFAKTLDMYPIKNLEDLYDKEGYRDSEFKKGDKGMWTIYTDFAKSNKPGELDDEGMVLNLDRNTRTAKGHYFVTTFYRNGKLPDEKNYKIEMKNNKIILLDEVKDDKLKQKIENFKFFGQYANLKELRKYNNGDVSINENVPSYDVEYKMSNKDEIVKELRSRYNISTEKSPILKMHIDGDLKGSSVGYRKLEIDFSKRENSKLSVIEFLSYKPAKK

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]