PangenomeCOLN315NCTC8325NewmanUSA300_FPR3757JSNZ04-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 06-JUL-2013

⊟Summary

• organism: Staphylococcus aureus Newman
• locus tag: NWMN_1714 [new locus tag: NWMN_RS09625 ]
• pan locus tag^?: SAUPAN004577000
• symbol: bsaC
• pan gene symbol^?: epiC
• synonym:
• product: lantibiotic biosynthesis protein

⊟Additional information (user-provided)

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: NWMN_1714 [new locus tag: NWMN_RS09625 ]
• symbol: bsaC
• product: lantibiotic biosynthesis protein
• replicon: chromosome
• strand: -
• coordinates: 1910298..1911542
• length: 1245
• essential: unknown other strains

⊟Accession numbers

• Gene ID: 5331785 NCBI
• RefSeq: YP_001332748 NCBI
• BioCyc:
• MicrobesOnline: 3707266 MicrobesOnline

⊟Phenotype

⊟Additional information (user-provided)

⊟DNA sequence

• 1
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  ATGATTGATATGAATCTAATATTGAAGAAGAAGTTTCAAGAGATTTCAGAAGTAGATGAT
  TTCATTTCAAAAGCATCTACTGAAACCGATTATTTTGAACCTTCAACTTTATCACATGGT
  ATACCAGGTATCATTTTGTTTTTAGATGCTTATCAAAAAGTTTTCGATATTAATACTGAG
  CAAATTGTGCATAAGTACATCATGAAATTAGCACCATATTTACAGAGTGGTCAATATAAC
  AATTCTTTGTTTGGTGGACTTTCAGGTATTGCATTTTCAATGGATTTAGCATCGCAAAAT
  GGCAAAAATTATCAAAATATTTTAAATAATATTGATGGTCACATTGTAAATGAAATAGAA
  AATAAATTTGATCAAATATTACAAGAACCATTAAATCCATTAAATTATGATACTGTCAGT
  GGATTAGCTGGGATAGGGAGATATTTGCTAAATAGAGTAGATGAGAATGAATTTAATGTT
  AAAGCATTAAAAAGCATATTAGTATACTTTAAAGATATTCAATATTCTAAAAATAGCTGG
  GTAGTCCCACAAGAAAGTCAATTTTTAGAGTCTGATAAAAATTATTTTACTGAAGGTAAT
  ATCAATCTTGGCCTTGCACATGGAGTGCTAGGACCGATGTCTTTATTTGCATTATGCGTG
  ATTAAAGGAATTACGATTGAAAATCATCAGCACATATTAAAAGACATGTACAAATTTATC
  ATGGACGAAAAATTTTGTAACCACGAAAGATGGTTGCAGCGTTACGATTTAATTTCTGAA
  CGTAATCATTTCAATTTTATTCGGAATGGTTGGTGTTATGGCAATACGGGTGTAATGACG
  ACGTTGTTTTTAATCGGCCAAGCATTACAAGATGATGAAATAATTAAAATGTCTAAAAAA
  GTGATGCTACAAGTAGTAAATGATAAAGATGAAAATTTAATAAGTCCAACTATTTGTCAT
  GGATTGTCATCACAAATATTAATGTTAACAATTATGAATTTGAATTTTGAATTAAATGAA
  GTGTCTGATTATATCACTGTATTAATAAATAAACTGATTTCTCATTATAAGGAAGATTAT
  CTGGTGAATTTTATAGACATTAATGAAAATAAGCAAGATGTATTTAAAAGTAGGAAAGTT
  GGCCTTTTAGAAGGTGAATTAGGGGTCTATCTAACATTGATGACACTGAAAAATACAAAA
  ATTCTCAATGAAAAAAATTGGACCAATGCGTTTTTAATTAGCTGA
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⊟Protein

⊟General

• locus tag: NWMN_1714 [new locus tag: NWMN_RS09625 ]
• symbol: BsaC
• description: lantibiotic biosynthesis protein
• length: 414
• theoretical pI: 5.15033
• theoretical MW: 47645.4
• GRAVY: -0.148309

⊟Function

• TIGRFAM:
  Cellular processes Cellular processes Toxin production and resistance type 2 lantibiotic biosynthesis protein LanM (TIGR03897; HMM-score: 60.8)
• TheSEED  :
  • Lanthionine biosynthesis cyclase LanC
• PFAM:
  6_Hairpin (CL0059) LANC_like; Lanthionine synthetase C-like protein (PF05147; HMM-score: 279.3)
  and 1 more
  no clan defined YppF; YppF-like protein (PF14178; HMM-score: 14.9)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• DeepLocPro: Cytoplasmic
  • Cytoplasmic Score: 0.4861
  • Cytoplasmic Membrane Score: 0.3403
  • Cell wall & surface Score: 0.0028
  • Extracellular Score: 0.1708
• LocateP: Intracellular
  • Prediction by SwissProt Classification: Cytoplasmic
  • Pathway Prediction: No pathway
  • Intracellular possibility: 1
  • Signal peptide possibility: -1
  • N-terminally Anchored Score: -1
  • Predicted Cleavage Site: No CleavageSite
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.001413
  • TAT(Tat/SPI): 0.000105
  • LIPO(Sec/SPII): 0.000432
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 151221926 NCBI
• RefSeq: YP_001332748 NCBI
• UniProt: A0A0H3K959 UniProt

⊟Additional information (user-provided)

⊟Protein sequence

• MIDMNLILKKKFQEISEVDDFISKASTETDYFEPSTLSHGIPGIILFLDAYQKVFDINTEQIVHKYIMKLAPYLQSGQYNNSLFGGLSGIAFSMDLASQNGKNYQNILNNIDGHIVNEIENKFDQILQEPLNPLNYDTVSGLAGIGRYLLNRVDENEFNVKALKSILVYFKDIQYSKNSWVVPQESQFLESDKNYFTEGNINLGLAHGVLGPMSLFALCVIKGITIENHQHILKDMYKFIMDEKFCNHERWLQRYDLISERNHFNFIRNGWCYGNTGVMTTLFLIGQALQDDEIIKMSKKVMLQVVNDKDENLISPTICHGLSSQILMLTIMNLNFELNEVSDYITVLINKLISHYKEDYLVNFIDINENKQDVFKSRKVGLLEGELGVYLTLMTLKNTKILNEKNWTNAFLIS

⊟Experimental data

• experimentally validated:
• protein localization:
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

• MicrobesOnline: bsaG < bsaE < bsaF < bsaP < bsaD < bsaC < bsaB < bsaA2

⊟Regulation

• regulator:

⊟Additional information (user-provided)

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Additional information (user-provided)

⊟Other information (user-provided)

You can add further information about the gene and protein here. [edit]

⊟Literature

⊟References

⊟Relevant publications