From AureoWiki
Jump to navigation Jump to search

FunGene: 08-OCT-2024

Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_002696
  • pan locus tag?: SAUPAN006486000
  • symbol: noc
  • pan gene symbol?: noc
  • synonym:
  • product: nucleoid occlusion protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_002696
  • symbol: noc
  • product: nucleoid occlusion protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2713154..2713993
  • length: 840
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    ATGAAAAAACCTTTTTCAAAATTATTTGGTTTGAAAAACAAAGATGACATCATTGGACAT
    ATTGAAGAAGATCGCAATAGTAATGTTGAATCCATTCAAATTGAACGTATCGTTCCCAAC
    CGTTATCAACCAAGACAGGTGTTTGAACCAAATAAAATTAAAGAACTTGCTGAATCAATA
    CATGAACATGGTTTACTACAACCTATTGTTGTAAGACCGATTGAAGAAGATATGTTTGAA
    ATTATTGCTGGAGAGCGCCGATTTAGAGCAATACAATCACTAAATTTACCTCAAGCAGAC
    GTTATTATTCGTGATATGGATGATGAAGAGACGGCTGTTGTTGCATTAATTGAGAATATT
    CAAAGAGAAAATTTGTCTGTTGTTGAAGAAGCGGAAGCCTATAAGAAATTATTGGAAATT
    GGTGATACAACGCAAAGTGAATTGGCAAAAAGTTTAGGTAAAAGTCAAAGCTTTATTGCA
    AATAAGTTGCGTTTATTGAAGTTGGCGCCGAAAGTACTACTTCGCTTAAGAGAAGGTAAA
    ATTACTGAACGCCATGCGAGAGCGGTATTATCATTGTCTGATAGCGAACAAGAAGCGTTG
    ATTGAGCAAGTCATTGCACAAAAGCTAAATGTGAAACAGACTGAAGATAGAGTACGCCAA
    AAAACGGGGCCTGAAAAGGTTAAAGCACAAAATTTACAGTTTGCACAAGATGTTACTCAA
    GCCCGAGACGAAGTAGGCAAAAGTATCCAAGCGATTCAACAAACAGGATTACATGTTGAG
    CATAAAGACAAAGATCATGAAGATTATTATGAAATAAAAATTCGAATATATAAACGTTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: JSNZ_002696
  • symbol: Noc
  • description: nucleoid occlusion protein
  • length: 279
  • theoretical pI: 6.6514
  • theoretical MW: 32168.5
  • GRAVY: -0.616487

Function[edit | edit source]

  • TIGRFAM:
    nucleoid occlusion protein (TIGR04285; HMM-score: 318.2)
    and 4 more
    ParB/RepB/Spo0J family partition protein (TIGR00180; HMM-score: 185)
    PRTRC system ParB family protein (TIGR03734; HMM-score: 140.7)
    Genetic information processing Mobile and extrachromosomal element functions Plasmid functions plasmid partitioning protein RepB (TIGR03454; HMM-score: 61.6)
    Signal transduction Regulatory functions DNA interactions CRISPR locus-related DNA-binding protein (TIGR01884; HMM-score: 14.8)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    ParBc (CL0248) ParBc; ParB/Sulfiredoxin domain (PF02195; HMM-score: 98.5)
    and 5 more
    HTH (CL0123) HTH_ParB; HTH domain found in ParB protein (PF17762; HMM-score: 61.4)
    KorB; KorB domain (PF08535; HMM-score: 19.1)
    TrmB; Sugar-specific transcriptional regulator TrmB (PF01978; HMM-score: 17)
    HTH_5; Bacterial regulatory protein, arsR family (PF01022; HMM-score: 14.9)
    HTH_3; Helix-turn-helix (PF01381; HMM-score: 14.1)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9918
    • Cytoplasmic Membrane Score: 0.0026
    • Cell wall & surface Score: 0.0015
    • Extracellular Score: 0.004
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006174
    • TAT(Tat/SPI): 0.000314
    • LIPO(Sec/SPII): 0.000923
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

Protein sequence[edit | edit source]

  • MKKPFSKLFGLKNKDDIIGHIEEDRNSNVESIQIERIVPNRYQPRQVFEPNKIKELAESIHEHGLLQPIVVRPIEEDMFEIIAGERRFRAIQSLNLPQADVIIRDMDDEETAVVALIENIQRENLSVVEEAEAYKKLLEIGDTTQSELAKSLGKSQSFIANKLRLLKLAPKVLLRLREGKITERHARAVLSLSDSEQEALIEQVIAQKLNVKQTEDRVRQKTGPEKVKAQNLQFAQDVTQARDEVGKSIQAIQQTGLHVEHKDKDHEDYYEIKIRIYKR

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]