PangenomeCOLN315NCTC8325NewmanUSA300_FPR3757JSNZ04-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

FunGene: 08-OCT-2024

⊟Summary

• organism: Staphylococcus aureus JSNZ
• locus tag: JSNZ_002521
• pan locus tag^?: SAUPAN006199000
• symbol: JSNZ_002521
• pan gene symbol^?: cidR
• synonym:
• product: LysR family transcriptional regulator

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: JSNZ_002521
• symbol: JSNZ_002521
• product: LysR family transcriptional regulator
• replicon: chromosome
• strand: -
• coordinates: 2526913..2527791
• length: 879
• essential: unknown other strains

⊟Accession numbers

• Gene ID:
• RefSeq:
• BioCyc:
• MicrobesOnline:

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  
  GTGGATATCAAACATATGAAATATTTTATTGAAGTCGTTAAGCAAGGAGGCATGACTAAT
  GCTTCCAAATCATTATATATTGCACAACCTACAATTAGTAAAGCAATTAAAGATATTGAA
  AATGAAATGGGCACGCCCTTATTTGATAGAAGTAAAAGACATTTAATTCTTACCGATGCA
  GGTCAAATTTTTTATGAGAAAAGTAAAGAAATTGTTGCACTGTATGATTATTTACCATCT
  GAAATGGAACGCTTGAATGGACTGGAAACAGGACATATAAACATGGGCATGTCGGCAGTC
  ATGAATATGAAGATTCTTATCAATATTCTTGGTGCATTCCATCAACAATATCCAAATGTT
  ACATATAATTTGATAGAAAATGGCGGTAAAACAATTGAACAGCAAATTATCAATGATGAA
  GTAGATATAGGCGTGACCACTTTGCCAGTCGATCATCATATTTTCGATTATACTACCCTA
  GATAAGGAAGATTTGCGACTTATCGTGAGCAGAGAGCATCGACTCGCAAAATATGAAACT
  GTTAAACTCGAAGATTTAGCAGGTGAAGACTTCATTTTATTTAATAAAGACTTTTACTTG
  AATGATAAAATTATTGAAAATGCTAAAAACGTTGGCTTTGTTCCGAATACTGTAGCGCAA
  ATTTCACAATGGCATGTTATAGAAGATTTAGTTACGAATGAATTAGGTATTAGTATTTTA
  CCAACATCAATTTCAGAGCAACTAAATGGAGATGTGAAGCTGCTACGCATTGAAGATGCT
  CATGTACATTGGGAATTAGGTGTTGTTTGGAAGAAGGATAAACAATTAAGTCATGCCACA
  ACGAAATGGATAGAATTTTTGAAAGACCGTTTAGGCTAA
  60
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  879
  

⊟Protein

⊟General

• locus tag: JSNZ_002521
• symbol: JSNZ_002521
• description: LysR family transcriptional regulator
• length: 292
• theoretical pI: 5.38489
• theoretical MW: 33471.2
• GRAVY: -0.236301

⊟Function

• TIGRFAM:
  Signal transduction Regulatory functions DNA interactions aminoethylphosphonate catabolism associated LysR family transcriptional regulator (TIGR03339; HMM-score: 131.9)
  and 9 more
  Metabolism Energy metabolism Other pca operon transcription factor PcaQ (TIGR02424; HMM-score: 89)
  Signal transduction Regulatory functions DNA interactions pca operon transcription factor PcaQ (TIGR02424; HMM-score: 89)
  putative choline sulfate-utilization transcription factor (TIGR03418; HMM-score: 57.1)
  Cellular processes Cellular processes Toxin production and resistance transcriptional regulator, ArgP family (TIGR03298; HMM-score: 43.9)
  Genetic information processing DNA metabolism DNA replication, recombination, and repair transcriptional regulator, ArgP family (TIGR03298; HMM-score: 43.9)
  Signal transduction Regulatory functions DNA interactions transcriptional regulator, ArgP family (TIGR03298; HMM-score: 43.9)
  Signal transduction Regulatory functions DNA interactions D-serine deaminase transcriptional activator (TIGR02036; HMM-score: 34.6)
  Metabolism Fatty acid and phospholipid metabolism Biosynthesis poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit (TIGR01836; HMM-score: 15)
  Signal transduction Regulatory functions Other ModE molybdate transport repressor domain (TIGR00637; HMM-score: 12.6)
• TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
• PFAM:
  PBP (CL0177) LysR_substrate; LysR substrate binding domain (PF03466; HMM-score: 155.3)
  and 2 more
  HTH (CL0123) HTH_1; Bacterial regulatory helix-turn-helix protein, lysR family (PF00126; HMM-score: 70)
  PBP (CL0177) PBP_like; PBP superfamily domain (PF12727; HMM-score: 11.2)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 9.97
  • Cytoplasmic Membrane Score: 0
  • Cellwall Score: 0.01
  • Extracellular Score: 0.02
  • Internal Helices: 0
• DeepLocPro: Cytoplasmic
  • Cytoplasmic Score: 0.9888
  • Cytoplasmic Membrane Score: 0.01
  • Cell wall & surface Score: 0.0001
  • Extracellular Score: 0.0011
• LocateP:
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.008057
  • TAT(Tat/SPI): 0.001993
  • LIPO(Sec/SPII): 0.001712
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI:
• RefSeq:
• UniProt:

⊟Protein sequence

• MDIKHMKYFIEVVKQGGMTNASKSLYIAQPTISKAIKDIENEMGTPLFDRSKRHLILTDAGQIFYEKSKEIVALYDYLPSEMERLNGLETGHINMGMSAVMNMKILINILGAFHQQYPNVTYNLIENGGKTIEQQIINDEVDIGVTTLPVDHHIFDYTTLDKEDLRLIVSREHRLAKYETVKLEDLAGEDFILFNKDFYLNDKIIENAKNVGFVPNTVAQISQWHVIEDLVTNELGISILPTSISEQLNGDVKLLRIEDAHVHWELGVVWKKDKQLSHATTKWIEFLKDRLG

⊟Experimental data

• experimentally validated: data available for COL, NCTC8325
• protein localization: data available for COL
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• data available for COL, Newman

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications