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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_002500
  • pan locus tag?: SAUPAN006168000
  • symbol: JSNZ_002500
  • pan gene symbol?: frp
  • synonym:
  • product: NAD(P)H-dependent oxidoreductase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_002500
  • symbol: JSNZ_002500
  • product: NAD(P)H-dependent oxidoreductase
  • replicon: chromosome
  • strand: -
  • coordinates: 2507617..2508288
  • length: 672
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    ATGAGCAATATGAATCAAACAATTATGGATGCATTTCATTTCAGACATGCGACTAAGCAA
    TTCGATCCACAAAAGAAAGTTTCGAAAGAAGATTTTGAAACAATATTAGAGTCAGGTAGA
    TTGTCTCCAAGTTCTCTTGGGTTAGAACCTTGGAAGTTTGTCGTGATTCAAGATCAAGCG
    TTACGTGATGAATTAAAAGCGCACAGTTGGGGCGCAGCAAAACAATTAGATACAGCGAGC
    CATTTTGTGCTAATTTTTGCGCGTAAAAATGTAACGTCAAGATCACCGTATGTACAACAT
    ATGTTAAGAGATATTAAAAAATATGAGGCACAAACGATTCCAGCTGTTGAACAAAAATTC
    GATGCATTCCAAGCAGATTTCCATATTTCTGATAATGATCAAGCCTTGTATGACTGGTCA
    AGTAAACAAACGTATATTGCATTAGGCAATATGATGACGACAGCCGCATTGTTAGGTATT
    GATTCATGTCCGATGGAAGGTTTTAGTCTGGATACAGTGACAGACATTTTAGCAAATAAA
    GGGATCTTAGATACTGAGCAATTTGGTTTATCAGTGATGGTCGCATTTGGCTACAGACAA
    CAAGTGCCACCGAAAAATAAAACACGCCAAGCTTATGAAGATGTTATTGAATGGGTTGGA
    CCAAAAGAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    672

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_002500
  • symbol: JSNZ_002500
  • description: NAD(P)H-dependent oxidoreductase
  • length: 223
  • theoretical pI: 5.94894
  • theoretical MW: 25358.6
  • GRAVY: -0.402691

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin 5,6-dimethylbenzimidazole synthase (TIGR02476; EC 1.14.99.40; HMM-score: 20)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    FMN-dep-NRtase (CL0529) Nitroreductase; Nitroreductase family (PF00881; HMM-score: 98.6)
    and 1 more
    TM1586_NiRdase; Putative TM nitroreductase (PF14512; HMM-score: 20.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9868
    • Cytoplasmic Membrane Score: 0.0046
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0086
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002464
    • TAT(Tat/SPI): 0.00023
    • LIPO(Sec/SPII): 0.000371
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MSNMNQTIMDAFHFRHATKQFDPQKKVSKEDFETILESGRLSPSSLGLEPWKFVVIQDQALRDELKAHSWGAAKQLDTASHFVLIFARKNVTSRSPYVQHMLRDIKKYEAQTIPAVEQKFDAFQADFHISDNDQALYDWSSKQTYIALGNMMTTAALLGIDSCPMEGFSLDTVTDILANKGILDTEQFGLSVMVAFGYRQQVPPKNKTRQAYEDVIEWVGPKE

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • data available for N315

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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