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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_002448
  • pan locus tag?: SAUPAN006037000
  • symbol: JSNZ_002448
  • pan gene symbol?: —
  • synonym:
  • product: AbgT family transporter

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_002448
  • symbol: JSNZ_002448
  • product: AbgT family transporter
  • replicon: chromosome
  • strand: +
  • coordinates: 2449890..2451428
  • length: 1539
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    ATGACATCAAAACATCAACAAAAGGGGTCTATCGTCAATCGTTTCTTGAATAGTGTTGAA
    AAAATCGGAAATAAATTGCCAGATCCTAGCGTCTTATTCTTTTTAATGTGTGTGGGCTTA
    GCCATTATGACATGGGTTATCTCATTATTTAATGTATCTGTTAAGCATCCAGGTACGCAT
    CAAACCATTTATATTAAAAATATAATTAGCCATGATGGATTTACGATGATAATGAATGAT
    ACGATTAAAAATTTCTCAGAGTTCCCAGCATTAGGCTTAGTACTAGCAGTGATGATTGGT
    ATTGGTGTTGCAGAGAAAACAGGATACTTCGATAAGTTAATGATTTCTGTTGTGAATCGC
    GCACCACGTTTCTTAATTTTACCGACTATTATATTAATTGGTATTTTAGGTAGTACAGCC
    GGCGATGCTGCGACAATTATCTTGCCGCCGCTTGCAGCAATGCTTTTTATTAAAATTGGC
    TATCACCCTATCGCTGGACTAACGATGGCATATGCTTCCGCTGTTGGAGGATTTGCAGCA
    AATATAGTTGTTGGTATGCAAGATGCTTTGGTCTATTCATTTACAGAACCGGCAACACGT
    ATCGTTTCAGATTCTATTAAAACAAACGTTGCTATGAACTGGTACTTTATCGCAGCGAGT
    GTCGTTGTATTACTTCCTACGATATTGCTAGTTACAACTAAGCTCATTATTCCTAGATTA
    GGAAAATATGATGACAGTTTAATGCATGATGACCATGAAGAAACATCTTCACATATTACT
    GACAAAGAAGCACATGCTTTAAAATGGGCAAATATCAGTTTCATAGTCACAATTATTTTA
    TTAATTATTACAGCCATTCCTGAACATAGCTTTTTAAGAAATGCTAAAACAGGCAGCTTA
    CTAGACGATGCGCCATTAATTAACGGTGTCGGATTAATTATTCTTGTCGTATTTTTAGTA
    CCTGGATTAGTTTATGGGATTTTAAGCAAAGAAATTAAAAATACAAAAGACTTAGGTAAA
    ATGTTCGGCGATGCTGTAGGATCAATGGGAACATTTATCGTTATTGTGTTTTTTGCAGCA
    CAGCTACTTGCGTATTTAAAGTGGAGTAATTTAGGAATTATCGCTGCTGTTAAAGGTGCC
    AAATTATTAGAACATCAAAACGGCATTGTATTGATACTAGGTATTATTGTACTAAGTGCA
    ATGGTCAACATGTTAATCGGAAGCGCATCGGCTAAATGGGGTATTTTAGGACCGATATTC
    GTACCAATGTTAATCCTTATCGGCTTTCATCCCGCATTCACACAAGTCATTTACCGTGTA
    GGCGATTCAATTACCAATCCAATTACACCGATGATGCCGTACTTACCTTTATTATTAACT
    TATGCACAAAAATACGATAAACGCATGAAACTCGGAGCCTTACTTTCTAGTTTAATGCCG
    TATTCAATCGCGCTAAGTATTGTGTGGACAGTATTTGTCATCATTTGGTTCCTATTAGGT
    ATTCCTGTTGGACCAGGTGGACCGATATTCGTTAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1539

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_002448
  • symbol: JSNZ_002448
  • description: AbgT family transporter
  • length: 512
  • theoretical pI: 9.7071
  • theoretical MW: 55574.3
  • GRAVY: 0.775391

⊟Function[edit | edit source]

  • TIGRFAM:
    Hypothetical proteins Conserved AbgT transporter family (TIGR00819; HMM-score: 447.5)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    IT (CL0182) ABG_transport; AbgT putative transporter family (PF03806; HMM-score: 729.4)
    and 3 more
    Na_H_antiporter; Na+/H+ antiporter family (PF03553; HMM-score: 27.1)
    DcuC; C4-dicarboxylate anaerobic carrier (PF03606; HMM-score: 21.6)
    no clan defined DUF6338; Family of unknown function (DUF6338) (PF19865; HMM-score: 7.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 11
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.9999
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0001
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004399
    • TAT(Tat/SPI): 0.000242
    • LIPO(Sec/SPII): 0.001808
  • predicted transmembrane helices (TMHMM): 12

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MTSKHQQKGSIVNRFLNSVEKIGNKLPDPSVLFFLMCVGLAIMTWVISLFNVSVKHPGTHQTIYIKNIISHDGFTMIMNDTIKNFSEFPALGLVLAVMIGIGVAEKTGYFDKLMISVVNRAPRFLILPTIILIGILGSTAGDAATIILPPLAAMLFIKIGYHPIAGLTMAYASAVGGFAANIVVGMQDALVYSFTEPATRIVSDSIKTNVAMNWYFIAASVVVLLPTILLVTTKLIIPRLGKYDDSLMHDDHEETSSHITDKEAHALKWANISFIVTIILLIITAIPEHSFLRNAKTGSLLDDAPLINGVGLIILVVFLVPGLVYGILSKEIKNTKDLGKMFGDAVGSMGTFIVIVFFAAQLLAYLKWSNLGIIAAVKGAKLLEHQNGIVLILGIIVLSAMVNMLIGSASAKWGILGPIFVPMLILIGFHPAFTQVIYRVGDSITNPITPMMPYLPLLLTYAQKYDKRMKLGALLSSLMPYSIALSIVWTVFVIIWFLLGIPVGPGGPIFVK

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: CodY (repression) regulon
    CodY(TF)important in Amino acid metabolism;  regulation predicted or transferred from N315 and NCTC 8325  [1]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Hannes Wolfgramm, Larissa Milena Busch, Jöran Tebben, Henry Mehlan, Lisa Hagenau, Thomas Sura, Tilly Hoffmüller, Elisa Bludau, Manuela Gesell Salazar, Alexander Reder, Stephan Michalik, Leif Steil, Kristin Surmann, Ulrike Mäder, Silva Holtfreter, Uwe Völker
    Integrated genomic and proteomic analysis of the mouse-adapted Staphylococcus aureus strain JSNZ.
    Curr Res Microb Sci: 2025, 9;100489
    [PubMed:41146725] [WorldCat.org] [DOI] (I e)

⊟Relevant publications[edit | edit source]

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