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FunGene: 08-OCT-2024
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus JSNZ
- locus tag: JSNZ_002358
- pan locus tag?: SAUPAN005920000
- symbol: JSNZ_002358
- pan gene symbol?: —
- synonym:
- product: MerR family transcriptional regulator
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: JSNZ_002358
- symbol: JSNZ_002358
- product: MerR family transcriptional regulator
- replicon: chromosome
- strand: +
- coordinates: 2356978..2357718
- length: 741
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID:
- RefSeq:
- BioCyc:
- MicrobesOnline:
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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721TTGGCATACACATACACTTTAAAAGATATTATTGAAATTACAGGTGTAACTAAAAGAACT
TTACATTATTACGATGAAATAGGATTATTAGTTCCAGATAAAAATGATAAAAATTATCGC
GTTTATAAACAGCAAGACTTAGAAAAATTACAAAAGATTTTAATACTCAAGTCTTTTGAT
TTTGATATCGCTAAAATAAAACAATACATTTCGTATGATAATGAACAATTGCGAAAGTTA
TTATCAGAGCAAATAAGCAAGTTAGATAAAAAGATTTCTGACTTACAATTAATTAGACGC
TCTGTATGTGAATTTATTAACGGACTCTCTCTAATAGATACCAGCATTTTAAACAAGACA
CTACAGTCACAATATGATAAAGAAGCATCTATAAAATATGGTCATACGGAAGCATATCAA
TCATTTATTAGACGTAAAGACAGCTTACAATCGCAGGATATCAGACATAAATTGACAACT
ATCTTCAATAAATTTAATCATATGTCTTTGAGTCATTATCCAATCCAAGATTGTAGTGAT
CTCGTATTTGAGTGGAAGGCATTTATGAACACTATCGCTGATTTTGATGATGAAACATTA
TGCTGTATTGCTAAAACATATGAAGATGATACGCGTTTCAAAGATTACTTTAATTCATAT
GATAATCAAAATTTAGCATCATACATTTCAGAAGCTGTTAATTATTTTTTGAGCAATGTG
AATAAGAGCGACAATTTTTAA60
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741
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: JSNZ_002358
- symbol: JSNZ_002358
- description: MerR family transcriptional regulator
- length: 246
- theoretical pI: 6.36347
- theoretical MW: 29113.8
- GRAVY: -0.552033
⊟Function[edit | edit source]
- TIGRFAM: Regulatory functions DNA interactions Cu(I)-responsive transcriptional regulator (TIGR02044; HMM-score: 44.6)Regulatory functions DNA interactions Cd(II)/Pb(II)-responsive transcriptional regulator (TIGR02047; HMM-score: 40.5)Cellular processes Detoxification Hg(II)-responsive transcriptional regulator (TIGR02051; HMM-score: 39.9)Regulatory functions DNA interactions Hg(II)-responsive transcriptional regulator (TIGR02051; HMM-score: 39.9)Regulatory functions DNA interactions Zn(II)-responsive transcriptional regulator (TIGR02043; HMM-score: 37.3)and 2 moreCellular processes Detoxification redox-sensitive transcriptional activator SoxR (TIGR01950; HMM-score: 21.4)Regulatory functions DNA interactions redox-sensitive transcriptional activator SoxR (TIGR01950; HMM-score: 21.4)
- TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
- PFAM: HTH (CL0123) MerR_1; MerR HTH family regulatory protein (PF13411; HMM-score: 63.9)no clan defined TipAS; TipAS antibiotic-recognition domain (PF07739; HMM-score: 58.8)and 5 moreHTH (CL0123) MerR; MerR family regulatory protein (PF00376; HMM-score: 45.5)MerR-DNA-bind; MerR, DNA binding (PF09278; HMM-score: 25.1)no clan defined MKT1_N; Temperature dependent protein affecting M2 dsRNA replication (PF12247; HMM-score: 15.4)HTH (CL0123) MerR_2; MerR HTH family regulatory protein (PF13591; HMM-score: 12.8)HTH_49; Cry35Ab1 HTH C-terminal domain (PF18010; HMM-score: 11.3)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.8196
- Cytoplasmic Membrane Score: 0.0308
- Cell wall & surface Score: 0.0038
- Extracellular Score: 0.1458
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.0016
- TAT(Tat/SPI): 0.00007
- LIPO(Sec/SPII): 0.000362
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq:
- UniProt:
⊟Protein sequence[edit | edit source]
- MAYTYTLKDIIEITGVTKRTLHYYDEIGLLVPDKNDKNYRVYKQQDLEKLQKILILKSFDFDIAKIKQYISYDNEQLRKLLSEQISKLDKKISDLQLIRRSVCEFINGLSLIDTSILNKTLQSQYDKEASIKYGHTEAYQSFIRRKDSLQSQDIRHKLTTIFNKFNHMSLSHYPIQDCSDLVFEWKAFMNTIADFDDETLCCIAKTYEDDTRFKDYFNSYDNQNLASYISEAVNYFLSNVNKSDNF
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- Operon-mapper [1] : JSNZ_002357 > JSNZ_002358
⊟Regulation[edit | edit source]
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
Bioinformatics: 2018, 34(23);4118-4120
[PubMed:29931111] [WorldCat.org] [DOI] (I p) - ↑ Hannes Wolfgramm, Larissa Milena Busch, Jöran Tebben, Henry Mehlan, Lisa Hagenau, Thomas Sura, Tilly Hoffmüller, Elisa Bludau, Manuela Gesell Salazar, Alexander Reder, Stephan Michalik, Leif Steil, Kristin Surmann, Ulrike Mäder, Silva Holtfreter, Uwe Völker
Integrated genomic and proteomic analysis of the mouse-adapted Staphylococcus aureus strain JSNZ.
Curr Res Microb Sci: 2025, 9;100489
[PubMed:41146725] [WorldCat.org] [DOI] (I e)