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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_002289
  • pan locus tag?: SAUPAN005801000
  • symbol: JSNZ_002289
  • pan gene symbol?: —
  • synonym:
  • product: bile acid:sodium symporter family protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_002289
  • symbol: JSNZ_002289
  • product: bile acid:sodium symporter family protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2284688..2285605
  • length: 918
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGTTTCAAAAATTGAGTATATTTGCCACGAAGAGTTTTTTGGTATGGATGTTAGTAGCA
    GCTGTTATTGGATTTATTTTTCCACAACATGTTGCGACATTAGGTAAATGGGTACCTTAT
    TTACTTGGTATTGTTATGTTAGGTATGGGATTAACAATTACACCTAATGATTTCAAAATG
    GTCTTTAAAGCACCTAGAGCAGTAATTATTGGTGTCTGTCTACAATTCAGTATTATGCCC
    ACATTAGCATTTATAATTGCAAAGTCTTTTCATTTACCACCTGATATTGCTGTTGGCGTA
    ATATTAGTTGGATGTTGTCCGGGTGGGACATCAAGTAATGTAATGAGTTATTTAGCCAAA
    GCTAACGTAGCACTTTCTGTTTCTATTACGACGGTCTCTACGTTGCTAGCGCCATTCGTT
    ACACCTGCGTTAATATATCTATTTGCAAATGAATGGTTGGAAGTATCTTTCTTGAGTATG
    TTGTGGTCAGTTGTTCAAGTTGTATTAATTCCAATTGCTTTAGGTATTGTTTTGCAAATT
    ATTAATCGTAAAATTGCTGAAAAAGCTTCTACAGCTTTGCCGATTATATCAGTTGTTGCT
    ATTTCATTAATTTTAGCAATAGTTGTAGGTGGCAGTAAGCACCAAATCTTAACTACAGGA
    TTATTAATATTTTTAGTAGTTATTTTACATAACGTATTAGGGTATACGATTGGATATTGG
    TTAGCTCGTCTTTTAAAATTAGATCGACAAGATCAAAAAGCAGTCAGTATTGAAGTTGGA
    ATGCAGAACTCTGGTTTAGCTGTGTCATTAGCAGCATTGCATTTTAATCCAATTGCAGCA
    GTACCAGGCGCAGTGTTTAGTTTCATTCATAATATAACAGGGCCTATTTTAGCAAAGTAT
    TGGTCAAAAAAGTTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    918

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_002289
  • symbol: JSNZ_002289
  • description: bile acid:sodium symporter family protein
  • length: 305
  • theoretical pI: 10.2753
  • theoretical MW: 32865.6
  • GRAVY: 1.0682

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids bile acid transporter (TIGR00841; HMM-score: 290)
    and 1 more
    membrane protein AbrB duplication (TIGR03082; HMM-score: 11.3)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    CPA_AT (CL0064) SBF; Sodium Bile acid symporter family (PF01758; HMM-score: 165.6)
    and 3 more
    SBF_like; SBF-like CPA transporter family (DUF4137) (PF13593; HMM-score: 79.3)
    Mem_trans; Membrane transport protein (PF03547; HMM-score: 16.4)
    no clan defined DUF3464; Photosynthesis affected mutant 68 (PF11947; HMM-score: 7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 8
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.9995
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0005
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.025516
    • TAT(Tat/SPI): 0.001144
    • LIPO(Sec/SPII): 0.015437
  • predicted transmembrane helices (TMHMM): 9

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MFQKLSIFATKSFLVWMLVAAVIGFIFPQHVATLGKWVPYLLGIVMLGMGLTITPNDFKMVFKAPRAVIIGVCLQFSIMPTLAFIIAKSFHLPPDIAVGVILVGCCPGGTSSNVMSYLAKANVALSVSITTVSTLLAPFVTPALIYLFANEWLEVSFLSMLWSVVQVVLIPIALGIVLQIINRKIAEKASTALPIISVVAISLILAIVVGGSKHQILTTGLLIFLVVILHNVLGYTIGYWLARLLKLDRQDQKAVSIEVGMQNSGLAVSLAALHFNPIAAVPGAVFSFIHNITGPILAKYWSKKL

⊟Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: CodY (repression) regulon
    CodY(TF)important in Amino acid metabolism;  regulation predicted or transferred from N315 and NCTC 8325  [2]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
    Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
    Bioinformatics: 2018, 34(23);4118-4120
    [PubMed:29931111] [WorldCat.org] [DOI] (I p)
  2. ↑ Hannes Wolfgramm, Larissa Milena Busch, Jöran Tebben, Henry Mehlan, Lisa Hagenau, Thomas Sura, Tilly Hoffmüller, Elisa Bludau, Manuela Gesell Salazar, Alexander Reder, Stephan Michalik, Leif Steil, Kristin Surmann, Ulrike Mäder, Silva Holtfreter, Uwe Völker
    Integrated genomic and proteomic analysis of the mouse-adapted Staphylococcus aureus strain JSNZ.
    Curr Res Microb Sci: 2025, 9;100489
    [PubMed:41146725] [WorldCat.org] [DOI] (I e)

⊟Relevant publications[edit | edit source]

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