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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_002094
  • pan locus tag?: SAUPAN005429000
  • symbol: JSNZ_002094
  • pan gene symbol?: hmrA
  • synonym:
  • product: M20 family metallopeptidase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_002094
  • symbol: JSNZ_002094
  • product: M20 family metallopeptidase
  • replicon: chromosome
  • strand: -
  • coordinates: 2106361..2107548
  • length: 1188
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGAGTGAAAAACAACAAATTCTCGATTATATAGAAACAAATAAATATAGTTATATCGAA
    ATCAGTCATAGAATTCATGAACGTCCTGAACTTGGTAATGAAGAAATATTTGCGTCTCGA
    ACTTTAATAGATCGTTTGAAAGAGCATGATTTTGAAATTGAAACCGAGATTGCTGGGCAT
    GCAACTGGGTTTATAGCGACATATGATTCAGGTCTTGACGGGCCAGCTATAGGTTTTTTA
    GCAGAATACGATGCTTTGCCAGGATTGGGTCATGCTTGTGGTCATAATATCATTGGAACT
    GCAAGTGTGCTTGGTGCAATTGGTTTGAAGCAAGTGATTGACCAAATTGGTGGTAAAGTA
    GTCGTTCTTGGATGTCCAGCTGAAGAAGGTGGGGAAAATGGTAGCGCTAAAGCTTCTTAT
    GTCAAGGCTGGTGTGATTGATCAAATAGACATTGCCTTAATGATTCATCCGGGAAATGAA
    ACTTATAAAACGATTGATACTTTGGCAGTGGATGTTTTAGATGTTAAATTTTACGGAAAA
    AGTGCTCATGCCTCTGAAAATGCAGATGAAGCGTTAAATGCATTAGACGCTATGATTAGT
    TATTTTAATGGTGTAGCACAACTACGACAACATATTAAAAAAGATCAACGTGTGCATGGT
    GTGATTTTAGATGGCGGGAAAGCAGCTAATATTATTCCAGACTATACACATGCTCGTTTT
    TATACTAGAGCAATGACGCGTAAAGAATTGGATATATTAACAGAAAAAGTAAATCAAATC
    GCACGTGGAGCTGCGATACAGACTGGTTGTGATTATGAATTTGGTCCAATTCAAAACGGT
    GTGAATGAATTCATTAAAACGCCGAAATTAGATGATTTATTTGCTAAATATGCTGAAGAA
    GTTGGTGAAGCAGTTATTGATGATGATGATTTTGGTTATGGCTCTACGGATACAGGGAAC
    GTAAGTCATGTTGTGCCAACAATACATCCTCATATTAAAATAGGATCACGTAATTTAGTA
    GGACATACGCATAGATTTAGAGAAGCGGCTGCGAGTGTACATGGTGATGAAGCATTAATT
    AAAGGTGCTAAAATAATGGCGTTGATGGGGTTAGAGTTAATTACAAATCAAGACGTTTAT
    CAAGACATTATTGAAGAGCATGCGCATTTGAAAGGGAATGGGAAGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1188

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_002094
  • symbol: JSNZ_002094
  • description: M20 family metallopeptidase
  • length: 395
  • theoretical pI: 5.07782
  • theoretical MW: 43014.1
  • GRAVY: -0.220253

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides amidohydrolase (TIGR01891; HMM-score: 203.7)
    and 4 more
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides peptidase, ArgE/DapE family (TIGR01910; EC 3.4.-.-; HMM-score: 44.7)
    Metabolism Amino acid biosynthesis Glutamate family acetylornithine deacetylase (ArgE) (TIGR01892; EC 3.5.1.16; HMM-score: 18.6)
    Metabolism Amino acid biosynthesis Aspartate family succinyl-diaminopimelate desuccinylase (TIGR01900; EC 3.5.1.18; HMM-score: 14.7)
    Metabolism Amino acid biosynthesis Aspartate family succinyl-diaminopimelate desuccinylase (TIGR01246; EC 3.5.1.18; HMM-score: 13.2)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    ZnExoPePases (CL0865) Peptidase_M20; Peptidase family M20/M25/M40 (PF01546; HMM-score: 35.1)
    no clan defined M20_dimer; Peptidase dimerisation domain (PF07687; HMM-score: 32.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9966
    • Cytoplasmic Membrane Score: 0.0014
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.0019
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002298
    • TAT(Tat/SPI): 0.000106
    • LIPO(Sec/SPII): 0.0002
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MSEKQQILDYIETNKYSYIEISHRIHERPELGNEEIFASRTLIDRLKEHDFEIETEIAGHATGFIATYDSGLDGPAIGFLAEYDALPGLGHACGHNIIGTASVLGAIGLKQVIDQIGGKVVVLGCPAEEGGENGSAKASYVKAGVIDQIDIALMIHPGNETYKTIDTLAVDVLDVKFYGKSAHASENADEALNALDAMISYFNGVAQLRQHIKKDQRVHGVILDGGKAANIIPDYTHARFYTRAMTRKELDILTEKVNQIARGAAIQTGCDYEFGPIQNGVNEFIKTPKLDDLFAKYAEEVGEAVIDDDDFGYGSTDTGNVSHVVPTIHPHIKIGSRNLVGHTHRFREAAASVHGDEALIKGAKIMALMGLELITNQDVYQDIIEEHAHLKGNGK

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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