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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_001594
  • pan locus tag?: SAUPAN004199000
  • symbol: pxpA
  • pan gene symbol?: pxpA
  • synonym:
  • product: 5-oxoprolinase subunit PxpA

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_001594
  • symbol: pxpA
  • product: 5-oxoprolinase subunit PxpA
  • replicon: chromosome
  • strand: -
  • coordinates: 1629452..1630204
  • length: 753
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGCGAGTTGATTTGAATTGTGATTTAGGCGAAGCATTTGGAAATTATTCCTTTGGTGGT
    GATCATCAAATTATTCCGTTAATTACAAGTGCGAATGTTGCTTGTGGTTTTCACGCTGGT
    GATGAAAATGTAATGAATGAAACGGTAAAACTTGCCAAAGCACATAATGTTGCAGTAGGT
    GCACATCCTGGTTTACCTGATTTGAAAGGCTTTGGCAGACGAAATATAGATATCTCTAAC
    GACGAGATTTATAATTTGATGATTTATCAATTAGGTGCATTACAAGGGTTTTGTCGCATT
    CATCAAGTTAAAATTAATCATGTTAAACCGCATGGTGCTTTGTATCAGATGGGTGCAAAA
    GACAGAGAAATAGCAAGCGTTATAGCACAAGCTGTTTATGACTTTGATCCATCACTAGTG
    TTAGTAGGATTAGCAAATTCATATCTAATTTCAGAAGCAAAGAATGTCGGATTAATTACA
    GCTTCTGAAGTGTTTGCTGATAGACGATACGAAGATGATGGGCAGCTCGTTAGTAGAAAA
    GAAAGTGATGCTGTGATTACTGATACTGACGAAGCACTTAAGCAGGTTTTAAAGATGGTG
    AAGGAAAATAAAGTTATTTCAAAAAACAATAAGGAAGTAACGTTACAAGCAGATACAATT
    TGTGTGCATGGTGATGGAGAACATGCATTATTATTTGTTTCGAAAATTAGAGAAATTTTA
    ATGAAAGAAGGCATTGATATTCAATCCTTATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    753

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_001594
  • symbol: PxpA
  • description: 5-oxoprolinase subunit PxpA
  • length: 250
  • theoretical pI: 5.55687
  • theoretical MW: 27421.1
  • GRAVY: -0.1016

⊟Function[edit | edit source]

  • reaction:
    EC 3.5.2.9?  ExPASy
    5-oxoprolinase (ATP-hydrolyzing) ATP + 5-oxo-L-proline + 2 H2O = ADP + phosphate + L-glutamate
  • TIGRFAM:
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    GH_CE (CL0158) LamB_YcsF; LamB/YcsF family (PF03746; HMM-score: 342)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.996
    • Cytoplasmic Membrane Score: 0.0001
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0038
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.034443
    • TAT(Tat/SPI): 0.006954
    • LIPO(Sec/SPII): 0.024372
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MRVDLNCDLGEAFGNYSFGGDHQIIPLITSANVACGFHAGDENVMNETVKLAKAHNVAVGAHPGLPDLKGFGRRNIDISNDEIYNLMIYQLGALQGFCRIHQVKINHVKPHGALYQMGAKDREIASVIAQAVYDFDPSLVLVGLANSYLISEAKNVGLITASEVFADRRYEDDGQLVSRKESDAVITDTDEALKQVLKMVKENKVISKNNKEVTLQADTICVHGDGEHALLFVSKIREILMKEGIDIQSL

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • data available for N315

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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