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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_001544
  • pan locus tag?: SAUPAN004134000
  • symbol: JSNZ_001544
  • pan gene symbol?: sodA
  • synonym:
  • product: superoxide dismutase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_001544
  • symbol: JSNZ_001544
  • product: superoxide dismutase
  • replicon: chromosome
  • strand: -
  • coordinates: 1580953..1581552
  • length: 600
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGGCTTTTGAATTACCAAAATTACCATACGCATTTGATGCATTAGAACCACATTTTGAC
    AAAGAAACTATGGAAATTCACCATGACAGACATCATAACACGTATGTTACGAAATTAAAT
    GCTGCAGTAGAAGGTACAGATTTAGAATCTAAATCTATTGAAGAAATTGTTGCTAATTTA
    GACAGTGTACCAGCTAACATCCAAACTGCTGTACGTAATAATGGCGGTGGACATTTAAAC
    CATTCATTATTCTGGGAGTTACTTTCACCAAACTCAGAAGAAAAAGGTACTGTAGTAGAA
    AAAATTAAAGAACAATGGGGTTCTTTAGAAGAATTTAAAAAAGAATTTGCTGACAAAGCA
    GCTGCACGCTTTGGTTCAGGTTGGGCTTGGTTAGTTGTAAACAATGGCCAGTTAGAAATT
    GTGACTACACCAAACCAAGATAATCCATTAACTGAGGGTAAAACACCTATTTTAGGTTTA
    GACGTATGGGAACACGCTTATTACCTAAAATATCAAAACAAACGCCCTGACTACATTGGC
    GCATTTTGGAATGTAGTTAACTGGGAAAAAGTTGACGAATTATATAATGCAACAAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_001544
  • symbol: JSNZ_001544
  • description: superoxide dismutase
  • length: 199
  • theoretical pI: 4.8565
  • theoretical MW: 22711.2
  • GRAVY: -0.575879

⊟Function[edit | edit source]

  • reaction:
    EC 1.15.1.1?  ExPASy
    Superoxide dismutase 2 superoxide + 2 H+ = O2 + H2O2
  • TIGRFAM:
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    no clan defined Sod_Fe_C; Iron/manganese superoxide dismutases, C-terminal domain (PF02777; HMM-score: 148)
    Sod_Fe_N; Iron/manganese superoxide dismutases, alpha-hairpin domain (PF00081; HMM-score: 119.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Extracellular
    • Cytoplasmic Score: 0.01
    • Cytoplasmic Membrane Score: 0.09
    • Cellwall Score: 0.18
    • Extracellular Score: 9.72
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9528
    • Cytoplasmic Membrane Score: 0.0004
    • Cell wall & surface Score: 0.0014
    • Extracellular Score: 0.0454
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002208
    • TAT(Tat/SPI): 0.0003
    • LIPO(Sec/SPII): 0.000241
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MAFELPKLPYAFDALEPHFDKETMEIHHDRHHNTYVTKLNAAVEGTDLESKSIEEIVANLDSVPANIQTAVRNNGGGHLNHSLFWELLSPNSEEKGTVVEKIKEQWGSLEEFKKEFADKAAARFGSGWAWLVVNNGQLEIVTTPNQDNPLTEGKTPILGLDVWEHAYYLKYQNKRPDYIGAFWNVVNWEKVDELYNATK

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: CodY (repression) regulon
    CodY(TF)important in Amino acid metabolism;  regulation predicted or transferred from N315 and NCTC 8325  [1]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Hannes Wolfgramm, Larissa Milena Busch, Jöran Tebben, Henry Mehlan, Lisa Hagenau, Thomas Sura, Tilly Hoffmüller, Elisa Bludau, Manuela Gesell Salazar, Alexander Reder, Stephan Michalik, Leif Steil, Kristin Surmann, Ulrike Mäder, Silva Holtfreter, Uwe Völker
    Integrated genomic and proteomic analysis of the mouse-adapted Staphylococcus aureus strain JSNZ.
    Curr Res Microb Sci: 2025, 9;100489
    [PubMed:41146725] [WorldCat.org] [DOI] (I e)

⊟Relevant publications[edit | edit source]

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