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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_001528
  • pan locus tag?: SAUPAN004116000
  • symbol: JSNZ_001528
  • pan gene symbol?: aroK
  • synonym:
  • product: shikimate kinase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_001528
  • symbol: JSNZ_001528
  • product: shikimate kinase
  • replicon: chromosome
  • strand: -
  • coordinates: 1569881..1570405
  • length: 525
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGAATCATGACAAATCACCAATAATTTTAATTGGTTTCATGGGTACCGGTAAATCTACG
    ATTGGTAAATACGTTGCAGATGAGCAAAATTTATCATTTATTGATATAGATTCATATATC
    GAAGAGAAGTATAAGTTAACAATACCAGAAATATTTAGTAAACATGGTGAACAATATTTC
    AGGAATTTAGAGTTCACATGTTTGCAAGAATGTATTAACACTGCAGATATAATTGCTACT
    GGTGGTGGTATTATTGAGAGTGAAGAGGCATTTAATTTTTTGAAAAATCAAAAAAACATT
    ATTTGGTTAGATTGTAATATTGATATTATATATAGTCGAATCAATGATGACCCACATCGA
    CCTAATGCAAATAATAAGACAATCAAGCAGTTAAATGACTTGTATTGCTCGCGGAATTTA
    AGATATAATGAAATCGCATTCAAGAAATTTGATAGTCATTTGCTATCAATTTCAGAAATA
    TATTATGAATTGCTAAATTTAATAAAAGCGAGTGATCAGTATTAG
    60
    120
    180
    240
    300
    360
    420
    480
    525

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_001528
  • symbol: JSNZ_001528
  • description: shikimate kinase
  • length: 174
  • theoretical pI: 4.87103
  • theoretical MW: 20205.8
  • GRAVY: -0.363218

⊟Function[edit | edit source]

  • reaction:
    EC 2.7.1.71?  ExPASy
    Shikimate kinase ATP + shikimate = ADP + shikimate 3-phosphate
  • TIGRFAM:
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Pantothenate and coenzyme A dephospho-CoA kinase (TIGR00152; EC 2.7.1.24; HMM-score: 19.8)
    carbohydrate kinase, thermoresistant glucokinase family (TIGR01313; EC 2.7.1.-; HMM-score: 19.5)
    putative cytidylate kinase (TIGR02173; EC 2.7.4.14; HMM-score: 17.8)
    and 1 more
    AAA family ATPase, CDC48 subfamily (TIGR01243; HMM-score: 9.5)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    P-loop_NTPase (CL0023) SKI; Shikimate kinase (PF01202; HMM-score: 158.6)
    and 7 more
    AAA_18; AAA domain (PF13238; HMM-score: 32.4)
    AAA; ATPase family associated with various cellular activities (AAA) (PF00004; HMM-score: 22.8)
    AAA_22; AAA domain (PF13401; HMM-score: 16.7)
    AAA_14; AAA domain (PF13173; HMM-score: 14.6)
    AAA_33; AAA domain (PF13671; HMM-score: 13.9)
    CoaE; Dephospho-CoA kinase (PF01121; HMM-score: 12.4)
    Cytidylate_kin; Cytidylate kinase (PF02224; HMM-score: 12.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9929
    • Cytoplasmic Membrane Score: 0.0002
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0069
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.020471
    • TAT(Tat/SPI): 0.000764
    • LIPO(Sec/SPII): 0.018107
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MNHDKSPIILIGFMGTGKSTIGKYVADEQNLSFIDIDSYIEEKYKLTIPEIFSKHGEQYFRNLEFTCLQECINTADIIATGGGIIESEEAFNFLKNQKNIIWLDCNIDIIYSRINDDPHRPNANNKTIKQLNDLYCSRNLRYNEIAFKKFDSHLLSISEIYYELLNLIKASDQY

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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