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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_001443
  • pan locus tag?: SAUPAN003918000
  • symbol: bshA
  • pan gene symbol?: bshA
  • synonym:
  • product: N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_001443
  • symbol: bshA
  • product: N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA
  • replicon: chromosome
  • strand: -
  • coordinates: 1490852..1491994
  • length: 1143
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGAAGATAGGTATAACATGTTACCCGTCCATGGGTGGTTCTGGAATTATTGCCACAGAA
    TTAGGAATTAAATTAGCAGAGCGAGGTCACGAAGTACATTTTATCACTTCAAATATCCCG
    TTTAGAATAAGAAAACCATTACCGAATATGATTTTTCATCAAGTTGAAGTGAATCAATAT
    GCAGTATTTCAGTATCCACCGTATGATATTACGTTAAGTACTAAAATCGCTGAAGTTATT
    AAAGAATATGATCTTGATTTGTTGCATATGCACTATGCTGTACCTCATGCAATTTGTGGG
    ATTTTAGCTCGTGAGATGTCAGGTAAAGATATAAAAATTATGACAACGCTACACGGTACT
    GATATTACTGTTTTGGGCTATGATCATTCACTCCAAGGTGCAATTAAATTTGGCATTGAA
    AAAAGTGATATTGTGACAAGTGTGAGTAAATCTTTAGCACAAGAAACACATGAAATTATT
    GAAACTAACAAAGAAATTATACCGATTTATAATTTTGTACGTGAAAATGAGTTTCCAACT
    AAACATAACACAGCACTAAAATCACAATTTGGTATAGCACCAGATGAAAAAGTGTTAATA
    CATGTATCGAATTTTAGACAAGTAAAACGCATAGATACTATTATAGAAACATTTGCAAAA
    GTACGTGAAAAGATACCTAGTAAATTAATTTTACTTGGAGATGGTCCTGAATTAGTGCCA
    ATGCGTCAATTGACGAAAGAGTTAAACGTAGAAGAGGATGTTTTATTTTTAGGGAAACAA
    GATTGCGTAAGTGAATTTTACCAATTATCTGACTTAGTATTATTATTAAGTGAAAAAGAA
    AGCTTTGGACTAACTTTACTTGAGGCTATGAAAACAGGCGTCGTTCCAATTGGTTCAAAT
    GCCGGTGGAATTAAAGAGGTTATTAAACATGGTGAAACTGGATTTGTCGTAGATGTGGGT
    GATTGTGATTCAGCGAGTGACTATGCTATCCGATTACTTGAAGATAAGGCGTTATACAAC
    AAACTTCAGAAAAACATGCTAGCAGATATTGCTGAACGTTTTGGATCAGAACTCATTACA
    GATCAATATGAGTATTATTATCAAAAAATGCTAAATGAGCATAACAAAAGTAAAGGCGAG
    TAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1143

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_001443
  • symbol: BshA
  • description: N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA
  • length: 380
  • theoretical pI: 5.75583
  • theoretical MW: 42767
  • GRAVY: -0.133947

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Glutathione and analogs N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA (TIGR03999; EC 2.4.1.-; HMM-score: 554)
    and 13 more
    sugar transferase, PEP-CTERM/EpsH1 system associated (TIGR03088; HMM-score: 94.1)
    glycosyltransferase, GG-Bacteroidales peptide system (TIGR04157; EC 2.4.1.-; HMM-score: 78.2)
    PEP-CTERM/exosortase A-associated glycosyltransferase, Daro_2409 family (TIGR04063; EC 2.4.-.-; HMM-score: 77.1)
    D-inositol-3-phosphate glycosyltransferase (TIGR03449; EC 2.4.1.250; HMM-score: 62.5)
    Metabolism Energy metabolism Biosynthesis and degradation of polysaccharides glycogen/starch synthase, ADP-glucose type (TIGR02095; EC 2.4.1.21; HMM-score: 62.2)
    Metabolism Energy metabolism Biosynthesis and degradation of polysaccharides glycogen synthase, Corynebacterium family (TIGR02149; HMM-score: 56.5)
    Genetic information processing Protein fate Protein modification and repair accessory Sec system glycosylation protein GtfA (TIGR02918; EC 2.4.1.-; HMM-score: 41.5)
    Unknown function Enzymes of unknown specificity glycosyltransferase, MSMEG_0565 family (TIGR04047; HMM-score: 39.2)
    Metabolism Energy metabolism Biosynthesis and degradation of polysaccharides sucrose synthase (TIGR02470; EC 2.4.1.13; HMM-score: 30.9)
    colanic acid biosynthesis glycosyltransferase WcaI (TIGR04007; EC 2.4.-.-; HMM-score: 29.7)
    sucrose-phosphate synthase, putative, glycosyltransferase domain (TIGR02472; EC 2.4.1.14; HMM-score: 27.8)
    sucrose phosphate synthase (TIGR02468; EC 2.4.1.14; HMM-score: 26.1)
    colanic acid biosynthesis glycosyltransferase WcaL (TIGR04005; EC 2.4.-.-; HMM-score: 24.5)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    GT-B (CL0113) Glycos_transf_1; Glycosyl transferases group 1 (PF00534; HMM-score: 133.8)
    and 7 more
    Glyco_trans_1_4; Glycosyl transferases group 1 (PF13692; HMM-score: 99.9)
    Glyco_transf_4; Glycosyltransferase Family 4 (PF13439; HMM-score: 75.3)
    Glyco_trans_4_2; Glycosyl transferase 4-like (PF13477; HMM-score: 49.6)
    Glyco_trans_4_4; Glycosyl transferase 4-like domain (PF13579; HMM-score: 32)
    Glyco_transf_5; Starch synthase catalytic domain (PF08323; HMM-score: 22.9)
    GT4-conflict; Family 4 Glycosyltransferase in conflict systems (PF20706; HMM-score: 18.7)
    NADP_Rossmann (CL0063) Pyr_redox; Pyridine nucleotide-disulphide oxidoreductase (PF00070; HMM-score: 14.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.7981
    • Cytoplasmic Membrane Score: 0.1569
    • Cell wall & surface Score: 0.0028
    • Extracellular Score: 0.0423
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.018066
    • TAT(Tat/SPI): 0.000537
    • LIPO(Sec/SPII): 0.004663
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKIGITCYPSMGGSGIIATELGIKLAERGHEVHFITSNIPFRIRKPLPNMIFHQVEVNQYAVFQYPPYDITLSTKIAEVIKEYDLDLLHMHYAVPHAICGILAREMSGKDIKIMTTLHGTDITVLGYDHSLQGAIKFGIEKSDIVTSVSKSLAQETHEIIETNKEIIPIYNFVRENEFPTKHNTALKSQFGIAPDEKVLIHVSNFRQVKRIDTIIETFAKVREKIPSKLILLGDGPELVPMRQLTKELNVEEDVLFLGKQDCVSEFYQLSDLVLLLSEKESFGLTLLEAMKTGVVPIGSNAGGIKEVIKHGETGFVVDVGDCDSASDYAIRLLEDKALYNKLQKNMLADIAERFGSELITDQYEYYYQKMLNEHNKSKGE

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
    Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
    Bioinformatics: 2018, 34(23);4118-4120
    [PubMed:29931111] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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