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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_001014
  • pan locus tag?: SAUPAN003257000
  • symbol: JSNZ_001014
  • pan gene symbol?: —
  • synonym:
  • product: acyltransferase family protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_001014
  • symbol: JSNZ_001014
  • product: acyltransferase family protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1016284..1017294
  • length: 1011
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGACTTCATTAAAAGAGAGAGATTATTTTTTTGACAACGCAAGAGCAATTTTAATATTA
    TTAGTCGTATTTGGACATATGTTACAACCCTACACGAGTGGCGATAAATATTTATCAGCA
    TTATACCTAGTTATTTATAGTTTCCATATGCCAACATTTTTGTTTATATCTGGTTATTTC
    GCGAAAAATATTGATAAACCATACTATTTAGAAAAAATTTCAAAACGTTTGATAGTACCT
    TATATGATATTTTTTGCATTCTTTTCAATTTATTATTTCTTAACAGGTAAAAGTGACGAA
    TTACAACTTGATCCTTTTAACCCAGTATTTGCGTTATGGTTTTTGATCACGCTATTTTTC
    TTTCATGTCATTTTAGTAATAGTTAGAAGATTTAATCCATATAAAGTGCTATCAGTTTCA
    ATTATTATATCTATTGGAGCAGGTTTTTCAGATAACATCGATAGCTACTTAAGCATTTCA
    AGGACAATCGTATTTTTCCCAATATTTTATCTAGGTTACATTTTCACCAAAAAACATACG
    GCTATTTTTAAAAATAAAAAACTAATACCAGTATCTATCATTACCTTTATTTTGTTTTTT
    ATCGTTTACGTGATTCATCCTATCAATGCAGATTGGTTATTAGGAAGTTCACCATATACT
    TCACTTGAAAATGAAGGACAGAGTGTATTCAGTCCTTTTAAACGACTTATATTATATGGA
    ATTATATTAATCGCAATGACTGCGTTTCTAAATTTAATGTCAACAAAGAAAAAATTATAT
    ACTTATATTGGTAGTCGTACGCTATACGTATATTTATTACATGGTTTAATTATTGGCATT
    GTTAGAGGATTTGAATGGTATCCATTCGATAATCCTATATCATTAATGACGTATCTTTAT
    TTAATAAGTATATCTGTAATCATCGTATATGTATTATCTACAAACTTTGTTTGTAAATGG
    ACAAATCCAATAATTAATTTACAAAGACCATCACAGTTTAAAGATTCATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1011

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_001014
  • symbol: JSNZ_001014
  • description: acyltransferase family protein
  • length: 336
  • theoretical pI: 9.78139
  • theoretical MW: 39241.3
  • GRAVY: 0.628274

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    Acyl_transf_3 (CL0316) Acyl_transf_3; Acyltransferase domain (PF01757; HMM-score: 100.6)
    and 1 more
    no clan defined MWFE; NADH-ubiquinone oxidoreductase MWFE subunit (PF15879; HMM-score: 7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 10
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.9995
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0004
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.026925
    • TAT(Tat/SPI): 0.001821
    • LIPO(Sec/SPII): 0.008489
  • predicted transmembrane helices (TMHMM): 10

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MTSLKERDYFFDNARAILILLVVFGHMLQPYTSGDKYLSALYLVIYSFHMPTFLFISGYFAKNIDKPYYLEKISKRLIVPYMIFFAFFSIYYFLTGKSDELQLDPFNPVFALWFLITLFFFHVILVIVRRFNPYKVLSVSIIISIGAGFSDNIDSYLSISRTIVFFPIFYLGYIFTKKHTAIFKNKKLIPVSIITFILFFIVYVIHPINADWLLGSSPYTSLENEGQSVFSPFKRLILYGIILIAMTAFLNLMSTKKKLYTYIGSRTLYVYLLHGLIIGIVRGFEWYPFDNPISLMTYLYLISISVIIVYVLSTNFVCKWTNPIINLQRPSQFKDS

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: GraR (repression) regulon
    GraR(response regulator)important in cationic antimicrobial peptide (CAMP) resistance;  [1]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Mélanie Falord, Ulrike Mäder, Aurélia Hiron, Michel Débarbouillé, Tarek Msadek
    Investigation of the Staphylococcus aureus GraSR regulon reveals novel links to virulence, stress response and cell wall signal transduction pathways.
    PLoS One: 2011, 6(7);e21323
    [PubMed:21765893] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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