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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_000931
  • pan locus tag?: SAUPAN003078000
  • symbol: JSNZ_000931
  • pan gene symbol?: —
  • synonym:
  • product: fumarylacetoacetate hydrolase family protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_000931
  • symbol: JSNZ_000931
  • product: fumarylacetoacetate hydrolase family protein
  • replicon: chromosome
  • strand: +
  • coordinates: 933745..934647
  • length: 903
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGAAATTCTTATCATTCAAGTATAATGACAAAACTTCATATGGCGTTAAAGTAAAACGC
    GAAGATGCTGTATGGGATTTAACACAAGTATTTGCTGACTTTGCAGAAGGAGATTTCCAT
    CCTAAAACATTGTTAGCTGGTTTACAACAAAATCATACTTTAGATTTTCAAGAACAAGTA
    CGTAAAGCAGTTGTAGCAGCAGAAGATAGCGGCAAAGCTGAAGACTATAAAATTTCATTT
    AATGACATTGAATTCTTACCACCAGTAACACCTCCGAATAATGTGATTGCTTTTGGTAGA
    AATTACAAAGATCATGCGAACGAATTAAATCATGAAGTAGAAAAATTATATGTATTTACA
    AAAGCAGCGTCATCTTTAACAGGAGATAATGCAACAATTCCAAATCATAAAGATATTACT
    GATCAATTAGATTATGAAGGTGAATTAGGTATTGTTATTGGTAAGTCTGGTGAAAAGATT
    CCAAAAGCATTAGCTTTAGATTATGTTTACGGCTATACAATTATTAACGATATCACTGAT
    CGCAAAGCACAAAGTGAACAAGATCAAGCATTTTTATCAAAAAGTTTAACTGGCGGTTGC
    CCAATGGGTCCTTATATCGTTACTAAAGACGAACTACCATTACCTGAAAATGTAAATATT
    GTTACAAAAGTTAACAATGAAATTAGACAAGATGGTAACACTGGCGAAATGATTCTTAAA
    ATTGATGAATTAATAGAAGAAATTTCAAAATATGTTGCATTACATCCGGGAGATATTATT
    GCAACTGGTACACCAGCAGGCGTTGGTGCAGGTATGCAACCACCTAAATTTTTACAACCA
    GGTGATGAAGTTAAAGTGACTATTGATAATATTGGAACACTGACAACTTATATCGCTAAA
    TAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    903

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_000931
  • symbol: JSNZ_000931
  • description: fumarylacetoacetate hydrolase family protein
  • length: 300
  • theoretical pI: 4.60314
  • theoretical MW: 33113.1
  • GRAVY: -0.368667

⊟Function[edit | edit source]

  • TIGRFAM:
    4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit (TIGR02303; EC 4.1.1.68,5.3.3.10; HMM-score: 174.5)
    and 2 more
    4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit (TIGR02305; EC 4.1.1.68,5.3.3.10; HMM-score: 96.8)
    Metabolism Energy metabolism Amino acids and amines fumarylacetoacetase (TIGR01266; EC 3.7.1.2; HMM-score: 18.5)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    FAH (CL0377) FAA_hydrolase; Fumarylacetoacetate (FAA) hydrolase C-terminal (PF01557; HMM-score: 217.8)
    and 1 more
    KH (CL0007) KH_2; KH domain (PF07650; HMM-score: 13)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9978
    • Cytoplasmic Membrane Score: 0.0004
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0017
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.00242
    • TAT(Tat/SPI): 0.000144
    • LIPO(Sec/SPII): 0.000406
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKFLSFKYNDKTSYGVKVKREDAVWDLTQVFADFAEGDFHPKTLLAGLQQNHTLDFQEQVRKAVVAAEDSGKAEDYKISFNDIEFLPPVTPPNNVIAFGRNYKDHANELNHEVEKLYVFTKAASSLTGDNATIPNHKDITDQLDYEGELGIVIGKSGEKIPKALALDYVYGYTIINDITDRKAQSEQDQAFLSKSLTGGCPMGPYIVTKDELPLPENVNIVTKVNNEIRQDGNTGEMILKIDELIEEISKYVALHPGDIIATGTPAGVGAGMQPPKFLQPGDEVKVTIDNIGTLTTYIAK

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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