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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_000925
  • pan locus tag?: SAUPAN003070000
  • symbol: JSNZ_000925
  • pan gene symbol?: pgi
  • synonym:
  • product: glucose-6-phosphate isomerase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_000925
  • symbol: JSNZ_000925
  • product: glucose-6-phosphate isomerase
  • replicon: chromosome
  • strand: +
  • coordinates: 922938..924269
  • length: 1332
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    ATGACTCATATTCAATTAGATTTTAGTAAAACGTTAGAATTTTTCGGTGAACACGAATTA
    AAACAACAACAAGAAATTGTTAAATCAATTCACAAAACAATTCATGAAGGTACTGGTGCA
    GGTAGTGACTTCTTAGGCTGGGTTGATTTACCAGTTGATTACGACAAAGAAGAATTTTCA
    AGAATTGTTGAAGCATCAAAACGCATTAAAGAAAATTCTGATGTTTTAGTAGTCATCGGT
    ATTGGTGGTTCTTACTTAGGTGCACGTGCAGCAATCGAAATGTTAACGTCATCATTTAGA
    AACAGCAATGAATACCCTGAAATTGTATTTGTTGGTAATCACTTATCATCAACATATACG
    AAAGAGTTAGTTGATTATTTAGCAGACAAAGATTTCTCTGTAAACGTTATTTCTAAATCT
    GGTACAACTACAGAACCAGCAGTTGCATTTAGATTGTTCAAACAATTAGTTGAAGAAAGA
    TACGGTAAAGAAGAAGCACAAAAACGTATATTTGCAACAACGGATAAAGAAAAAGGTGCT
    TTAAAACAGTTGGCTACAAACGAAGGTTATGAAACGTTTATCGTACCTGATGATGTAGGT
    GGAAGATATTCTGTTTTAACAGCAGTAGGATTATTACCAATTGCAACAGCTGGAATTAAC
    ATCGAAGCTATGATGATTGGTGCTGCAAAAGCACGTGAAGAATTATCTTCAGATAAATTA
    GAAGAAAACATTGCATACCAATATGCGACAATTCGAAACATTTTATATGCAAAAGGTTAT
    ACAACAGAAATGTTGATTAACTATGAACCATCTATGCAATACTTTAATGAATGGTGGAAA
    CAATTATTTGGTGAATCAGAAGGTAAAGACTTCAAAGGTATCTATCCTTCAAGTGCCAAC
    TACACAACTGATTTACATTCTTTAGGTCAATATGTACAAGAAGGCCGTCGTTTCTTATTC
    GAAACAGTGGTAAAAGTAAATCATCCTAAATATGATATTACTATTGAAAAAGATAGTGAT
    GATCTAGACGGATTAAATTATTTGGCTGGTAAAACAATCGACGAAGTTAACACAAAAGCA
    TTCGAAGGTACATTATTAGCGCATACTGATGGTGGTGTTCCTAACATGGTAGTGAACATT
    CCACAATTAGATGAAGAAACTTTCGGTTATGTCGTATACTTCTTCGAACTTGCTTGTGCA
    ATGAGTGGATACCAATTAGGTGTAAATCCATTTAACCAACCTGGTGTAGAAGCATATAAA
    CAAAACATGTTCGCATTATTAGGTAAACCTGGTTTTGAAGACTTGAAAAAAGAATTAGAA
    GAGCGTTTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1332

⊟Protein[edit | edit source]

Protein Data Bank: 3FF1

⊟General[edit | edit source]

  • locus tag: JSNZ_000925
  • symbol: JSNZ_000925
  • description: glucose-6-phosphate isomerase
  • length: 443
  • theoretical pI: 4.54735
  • theoretical MW: 49807.8
  • GRAVY: -0.325959

⊟Function[edit | edit source]

  • reaction:
    EC 5.3.1.9?  ExPASy
    Glucose-6-phosphate isomerase D-glucose 6-phosphate = D-fructose 6-phosphate
  • TIGRFAM:
    bifunctional phosphoglucose/phosphomannose isomerase (TIGR02128; EC 5.3.1.9; HMM-score: 25.6)
    and 1 more
    dihydroxyacetone kinase, phosphotransfer subunit (TIGR02364; HMM-score: 13.8)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    SIS (CL0067) PGI; Phosphoglucose isomerase (PF00342; HMM-score: 81.5)
    and 2 more
    GT-B (CL0113) Glyco_trans_4_2; Glycosyl transferase 4-like (PF13477; HMM-score: 14.2)
    EDD (CL0245) EIIA-man; PTS system fructose IIA component (PF03610; HMM-score: 13.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9887
    • Cytoplasmic Membrane Score: 0.0063
    • Cell wall & surface Score: 0.0004
    • Extracellular Score: 0.0045
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.00213
    • TAT(Tat/SPI): 0.000403
    • LIPO(Sec/SPII): 0.000235
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MTHIQLDFSKTLEFFGEHELKQQQEIVKSIHKTIHEGTGAGSDFLGWVDLPVDYDKEEFSRIVEASKRIKENSDVLVVIGIGGSYLGARAAIEMLTSSFRNSNEYPEIVFVGNHLSSTYTKELVDYLADKDFSVNVISKSGTTTEPAVAFRLFKQLVEERYGKEEAQKRIFATTDKEKGALKQLATNEGYETFIVPDDVGGRYSVLTAVGLLPIATAGINIEAMMIGAAKAREELSSDKLEENIAYQYATIRNILYAKGYTTEMLINYEPSMQYFNEWWKQLFGESEGKDFKGIYPSSANYTTDLHSLGQYVQEGRRFLFETVVKVNHPKYDITIEKDSDDLDGLNYLAGKTIDEVNTKAFEGTLLAHTDGGVPNMVVNIPQLDEETFGYVVYFFELACAMSGYQLGVNPFNQPGVEAYKQNMFALLGKPGFEDLKKELEERL

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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