From AureoWiki
Jump to navigation Jump to search
PangenomeCOLN315NCTC8325NewmanUSA300_FPR3757JSNZ04-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

FunGene: 08-OCT-2024

Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_000697
  • pan locus tag?: SAUPAN002625000
  • symbol: JSNZ_000697
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_000697
  • symbol: JSNZ_000697
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 732940..733185
  • length: 246
  • essential: unknown

Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    TTGATTTTCCTAACTTATTGGTGTGTTTTTCATTTAGCATACATAATAGGTTACATTAAA
    ATAACATTTTATACCAAAGTACACCAAAAGAATATTAGTACACGAATTAAACAACATTTT
    TATAGAAACCTATTGCACTTTAACGTCAATAAGTATATTTTTATATTATCTCTAATTAAT
    TGTGCGCACTTAATAACAGAATATTCTCAATATTTTTATTTTTTTGTGATTTGTTGGGAT
    ATTTAG
    60
    120
    180
    240
    246

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: JSNZ_000697
  • symbol: JSNZ_000697
  • description: hypothetical protein
  • length: 81
  • theoretical pI: 9.34945
  • theoretical MW: 10087.9
  • GRAVY: 0.503704

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED:
  • PFAM:
    no clan defined PRA1; PRA1 family protein (PF03208; HMM-score: 7.3)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.32
    • Cytoplasmic Membrane Score: 9.55
    • Cellwall Score: 0.12
    • Extracellular Score: 0.01
    • Internal Helix: 1
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.6078
    • Cytoplasmic Membrane Score: 0.1151
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.2771
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.009983
    • TAT(Tat/SPI): 0.000209
    • LIPO(Sec/SPII): 0.028035
  • predicted transmembrane helices (TMHMM): 2

Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

Protein sequence[edit | edit source]

  • MIFLTYWCVFHLAYIIGYIKITFYTKVHQKNISTRIKQHFYRNLLHFNVNKYIFILSLINCAHLITEYSQYFYFFVICWDI

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator: LexA (repression) regulon
    LexA(TF)important in SOS response;  regulation predicted or transferred from N315 and NCTC 8325  [2]

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

Literature[edit | edit source]

References[edit | edit source]

  1. Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
    Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
    Bioinformatics: 2018, 34(23);4118-4120
    [PubMed:29931111] [WorldCat.org] [DOI] (I p)
  2. Hannes Wolfgramm, Larissa Milena Busch, Jöran Tebben, Henry Mehlan, Lisa Hagenau, Thomas Sura, Tilly Hoffmüller, Elisa Bludau, Manuela Gesell Salazar, Alexander Reder, Stephan Michalik, Leif Steil, Kristin Surmann, Ulrike Mäder, Silva Holtfreter, Uwe Völker
    Integrated genomic and proteomic analysis of the mouse-adapted Staphylococcus aureus strain JSNZ.
    Curr Res Microb Sci: 2025, 9;100489
    [PubMed:41146725] [WorldCat.org] [DOI] (I e)

Relevant publications[edit | edit source]