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FunGene: 08-OCT-2024
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus JSNZ
- locus tag: JSNZ_000368
- pan locus tag?: SAUPAN002129000
- symbol: JSNZ_000368
- pan gene symbol?: ssl11
- synonym:
- product: superantigen-like protein SSL11
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: JSNZ_000368
- symbol: JSNZ_000368
- product: superantigen-like protein SSL11
- replicon: chromosome
- strand: +
- coordinates: 401612..402304
- length: 693
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID:
- RefSeq:
- BioCyc:
- MicrobesOnline:
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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661ATGAAATTAAAAAATATTGCTAAAGCAAGTTTAGCACTAGGGATTTTAACAACAGGGATG
ATTACAACTACTGCTCAGCCAGTAAAAGCAGACGAAACTAGTAGCAGATTAGCAGTTACT
TCAAAAGATACACAAGAATTAAAAAAATACTACAGTGGAACAGGATATAATTTTCAAAAT
GTAAGTGGCTATAGTGAAAACGACAAAATGAATGTATTTTTCGGACCACAACTTAATGTA
ATATCATTGCTTGGTTCAGATAAAGAGAGATTTAAAGATGGTGATTATAATGGACTAGAT
GTATTTGTCGTACGTGAAGGATCTGGTAGACAAGCAGATAATAATTCAATAGGTGGAATT
ACAAAGACAAATAAAAATGGTTATACAGATTTCGTAAAAAATGTTGGTTTAGAAATAACA
AAACCAACAGGACATAATACAGCAACAAGACAAGCAGAAACTTATAGTATTAATAAAGAA
GAAATTTCATTAAAAGAATTAGATTTCAAATTAAGAAAGCACTTAATTGACAATAACGGT
TTATATAACACTGAGCCTAAAGATAGCAAAATAAAAGTGACTATGCAAAATGGTGATTTT
TATACTTTTGAATTGAATAAAAAGTTACAAACTCATCGTATGGGTGATGTGATTGATGGT
AGAAATATAGAGAAAATTGAAGTGAATTTATAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: JSNZ_000368
- symbol: JSNZ_000368
- description: superantigen-like protein SSL11
- length: 230
- theoretical pI: 9.3434
- theoretical MW: 25693.7
- GRAVY: -0.667391
⊟Function[edit | edit source]
- TIGRFAM:
- TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
- PFAM: Ubiquitin (CL0072) Stap_Strp_tox_C; Staphylococcal/Streptococcal toxin, beta-grasp domain (PF02876; HMM-score: 102.1)and 2 moreOB_enterotoxin (CL0658) SSL_OB; Staphylococcal superantigen-like OB-fold domain (PF09199; HMM-score: 77)no clan defined MAP; MAP domain (PF03642; HMM-score: 13.8)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Extracellular
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 0
- Cellwall Score: 0
- Extracellular Score: 10
- Internal Helices: 0
- DeepLocPro: Extracellular
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 0.0005
- Cell wall & surface Score: 0.0055
- Extracellular Score: 0.9939
- LocateP:
- SignalP: Signal peptide SP(Sec/SPI) length 30 aa
- SP(Sec/SPI): 0.994092
- TAT(Tat/SPI): 0.003329
- LIPO(Sec/SPII): 0.001985
- Cleavage Site: CS pos: 30-31. VKA-DE. Pr: 0.9617
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq:
- UniProt:
⊟Protein sequence[edit | edit source]
- MKLKNIAKASLALGILTTGMITTTAQPVKADETSSRLAVTSKDTQELKKYYSGTGYNFQNVSGYSENDKMNVFFGPQLNVISLLGSDKERFKDGDYNGLDVFVVREGSGRQADNNSIGGITKTNKNGYTDFVKNVGLEITKPTGHNTATRQAETYSINKEEISLKELDFKLRKHLIDNNGLYNTEPKDSKIKVTMQNGDFYTFELNKKLQTHRMGDVIDGRNIEKIEVNL
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator: SaeR (activation) regulon
SaeR (TF) important in Virulence; transcription unit predicted or transferred from N315 and NCTC 8325 in Wolfgramm et al. (https://doi.org/10.1101/2025.09.03.674026)
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
⊟Relevant publications[edit | edit source]
Stefan Monecke, Peter Slickers, Ralf Ehricht
Assignment of Staphylococcus aureus isolates to clonal complexes based on microarray analysis and pattern recognition.
FEMS Immunol Med Microbiol: 2008, 53(2);237-51
[PubMed:18507678] [WorldCat.org] [DOI] (P p)