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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_000278
  • pan locus tag?: SAUPAN001855000
  • symbol: JSNZ_000278
  • pan gene symbol?: —
  • synonym:
  • product: LLM class flavin-dependent oxidoreductase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_000278
  • symbol: JSNZ_000278
  • product: LLM class flavin-dependent oxidoreductase
  • replicon: chromosome
  • strand: +
  • coordinates: 315011..316012
  • length: 1002
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    TTGGTTAAATTAAGCGTATTAGACTATGCCTTAATAGATGAAGGTAAGGATGCAGAAAAG
    GCATTGCAAGATTCAGTGACACTTGCAAAATTAGCAGATCGACTTGGCTTTAAGCGAATT
    TGGTTTACGGAACATCATAATGTACCAGCGTTTGCGTGTAGTAGTCCAGAACTTTTGATG
    ATGCATACATTGGCGCAGACAAATCACATACGAGTTGGCTCTGGTGGTGTGATGCTGCCG
    CACTATCGACCTTATAAAATTGCTGAGCATTTTAGAATGATGGCAGCGTTATATCCAAAT
    CGTATTGATTTAGGTATTGGTAATAATCCAGGTACTACTATGGTAAAGCAAGCTTTAGAT
    GGAATAAATCCTACATATGATAGTTACGATGAATCGATTTCGTTATTACGTGATTATCTT
    ACAATAAAGGATAAACCAAGTGCGCATACGTTAGGTGTCCAACCACACATTGATCATTTT
    CCAGAAATGTGGTTATTAAGTAGTAGCGCAACATCTGCCAAAATAGCTGCCGAACTAGGT
    ATAGGGCTTTCTGTTGGCACATTTTTGCTACCAGATATAAATGCGATACATGCAGCGAAG
    GATAACATTGATATTTACAAAAAACATTTCCAAGCATCAACGATTAAAATGGACGAAAAG
    GTGATGGCATCTGTATTTGTCATTGTAGCTGATAATGAAGCGGAAGTAGCAGCATTGCAA
    CATGCCTTAGATGTTTGGTTATTAGGTAAATTACAATTTGCAGAATTTGAACATTTTCCA
    TCGGTAGACACAGCACAAAAGTATAAGCTTAATGATCGAGACAAAGAGATGATTCAAGCA
    CATCAAGCACGCATCATTGCAGGTACACAAGAACAGGTTAAAACACGATTAGATGATTTC
    ATTGCTACGTTTGAAGTTGATGAGGTGTTAGTAGCACCGCTTATTCCAGGCATTGAACAG
    CGTTGTAAAACATTAAAATTACTCGCGGAAATCTATTTGTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1002

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_000278
  • symbol: JSNZ_000278
  • description: LLM class flavin-dependent oxidoreductase
  • length: 333
  • theoretical pI: 6.14577
  • theoretical MW: 37208.7
  • GRAVY: -0.0561562

⊟Function[edit | edit source]

  • reaction:
    EC 1.-.-.-?  ExPASy
  • TIGRFAM:
    Unknown function Enzymes of unknown specificity luciferase family oxidoreductase, group 1 (TIGR03558; EC 1.-.-.-; HMM-score: 348.4)
    and 20 more
    Unknown function Enzymes of unknown specificity putative FMN-dependent luciferase-like monooxygenase, KPN_01858 family (TIGR04027; EC 1.-.-.-; HMM-score: 49)
    natural product biosynthesis luciferase-like monooxygenase domain (TIGR04020; EC 1.-.-.-; HMM-score: 43.1)
    Unknown function Enzymes of unknown specificity putative luciferase-like monooxygenase, FMN-dependent, CE1758 family (TIGR04036; EC 1.-.-.-; HMM-score: 41.4)
    probable oxidoreductase, LLM family (TIGR03858; EC 1.-.-.-; HMM-score: 38.8)
    Unknown function Enzymes of unknown specificity probable F420-dependent oxidoreductase, MSMEG_3544 family (TIGR03854; HMM-score: 35.7)
    Unknown function Enzymes of unknown specificity probable F420-dependent oxidoreductase, Rv3093c family (TIGR03841; EC 1.-.-.-; HMM-score: 34)
    Unknown function Enzymes of unknown specificity probable F420-dependent oxidoreductase, MSMEG_4141 family (TIGR03620; HMM-score: 28.3)
    TAT-translocated F420-dependent dehydrogenase, FGD2 family (TIGR04465; EC 1.-.-.-; HMM-score: 27)
    Unknown function Enzymes of unknown specificity F420-dependent oxidoreductase, MSMEG_4879 family (TIGR03564; EC 1.-.-.-; HMM-score: 25.8)
    Unknown function Enzymes of unknown specificity probable F420-dependent oxidoreductase, Rv2161c family (TIGR03619; EC 1.-.-.-; HMM-score: 24.8)
    Metabolism Energy metabolism Methanogenesis 5,10-methylenetetrahydromethanopterin reductase (TIGR03555; EC 1.5.98.2; HMM-score: 24.2)
    Metabolism Energy metabolism Pentose phosphate pathway glucose-6-phosphate dehydrogenase (coenzyme-F420) (TIGR03554; EC 1.1.98.2; HMM-score: 22.8)
    Unknown function Enzymes of unknown specificity luciferase-type oxidoreductase, BA3436 family (TIGR03571; EC 1.-.-.-; HMM-score: 22.3)
    Unknown function Enzymes of unknown specificity probable F420-dependent oxidoreductase, MSMEG_2249 family (TIGR03857; HMM-score: 20.8)
    Unknown function Enzymes of unknown specificity F420-dependent oxidoreductase, CPS_4043 family (TIGR03842; HMM-score: 18.1)
    Unknown function Enzymes of unknown specificity probable F420-dependent oxidoreductase, MSMEG_2516 family (TIGR03621; HMM-score: 16.1)
    Unknown function Enzymes of unknown specificity probable F420-dependent oxidoreductase, Rv3520c family (TIGR03559; HMM-score: 13.8)
    Unknown function Enzymes of unknown specificity probable F420-dependent oxidoreductase, Rv1855c family (TIGR03560; HMM-score: 13.1)
    Unknown function Enzymes of unknown specificity FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family (TIGR03860; EC 1.-.-.-; HMM-score: 12.1)
    Unknown function Enzymes of unknown specificity coenzyme F420-dependent oxidoreductase, NP1902A family (TIGR04024; EC 1.14.-.-; HMM-score: 11)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    TIM_barrel (CL0036) Bac_luciferase; Luciferase-like monooxygenase (PF00296; HMM-score: 116.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9783
    • Cytoplasmic Membrane Score: 0.0063
    • Cell wall & surface Score: 0.0003
    • Extracellular Score: 0.0151
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004896
    • TAT(Tat/SPI): 0.000326
    • LIPO(Sec/SPII): 0.000528
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MVKLSVLDYALIDEGKDAEKALQDSVTLAKLADRLGFKRIWFTEHHNVPAFACSSPELLMMHTLAQTNHIRVGSGGVMLPHYRPYKIAEHFRMMAALYPNRIDLGIGNNPGTTMVKQALDGINPTYDSYDESISLLRDYLTIKDKPSAHTLGVQPHIDHFPEMWLLSSSATSAKIAAELGIGLSVGTFLLPDINAIHAAKDNIDIYKKHFQASTIKMDEKVMASVFVIVADNEAEVAALQHALDVWLLGKLQFAEFEHFPSVDTAQKYKLNDRDKEMIQAHQARIIAGTQEQVKTRLDDFIATFEVDEVLVAPLIPGIEQRCKTLKLLAEIYL

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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