PangenomeCOLN315NCTC8325NewmanUSA300_FPR3757JSNZ04-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 22-FEB-2026

⊟Summary

• organism: Staphylococcus aureus JSNZ
• locus tag: EGJ38_RS10795 [old locus tag: EGJ38_002163 ]
• pan locus tag^?: SAUPAN005589000
• symbol: lacC
• pan gene symbol^?: lacC
• synonym:
• product: tagatose-6-phosphate kinase

⊟Additional information (user-provided)

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: EGJ38_RS10795 [old locus tag: EGJ38_002163 ]
• symbol: lacC
• product: tagatose-6-phosphate kinase
• replicon: chromosome
• strand: -
• coordinates: 2181910..2182842
• length: 933
• essential: unknown other strains

⊟Accession numbers

• Location: NZ_CM129921 (2181910..2182842) NCBI
• BioCyc:
• MicrobesOnline:

⊟Phenotype

⊟Additional information (user-provided)

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  901
  
  ATGATTTTAACTTTAACATTAAATCCATCCGTTGATATTTCATATCCATTAACAGCATTG
  AAATTAGATGATGTTAATCGTGTTCAAGAAGTAAGTAAAACAGCTGGTGGTAAAGGTTTA
  AATGTAACAAGAGTACTTGCGCAAGTAGGTGAGCCAGTCCTTGCGAGTGGTTTTATTGGC
  GGTGAATTAGGTCAATTTATTGCTAAAAAATTAGATCATGCCGACATCAAGCATGCATTT
  TATAACATTAAGGGTGAAACACGAAACTGCATTGCAATTTTACATGAAGGGCAACAAACA
  GAAATTTTAGAGCAGGGACCGGAGATTGATAATCAAGAGGCTGCAGGATTTATTAAACAT
  TTTGAGCAATTATTAGAAAAAGTTGAAGCAGTTGCTATTTCAGGTAGCTTACCTAAAGGA
  TTAAATCAAGATTATTATGCACAAATTATTGAACGATGCCAAAACAAAGGTGTGCCTGTG
  ATATTGGACTGCTCGGGTGCAACTTTGCAAACAGTTTTGGAAAATCCATACAAACCAACA
  GTCATTAAACCAAACATTTCTGAACTATATCAATTGCTTAACCAGCCACTTGATGAAAGT
  TTAGAAAGTTTGAAACAGGCAGTGTCACAACCCTTATTCGAAGGGATTGAGTGGATTATT
  GTGTCTTTAGGTGCACAAGGTGCATTAGCTAAGCACAATCATACATTCTATAGAGTGAAT
  ATTCCGACAATAAGCGTATTAAATCCGGTTGGTTCAGGTGATTCTACAGTTGCTGGAATT
  ACTTCAGCAATTCTCAATCATGAAAACGACCACGATTTACTAAAAAAAGCTAATACTTTA
  GGCATGCTGAATGCGCAAGAAGCACAAACAGGATATGTCAATTTAAATAATTATGATGAA
  TTATTCAATCAAATTGAAGTTTTAGAGGTGTAA
  60
  120
  180
  240
  300
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  480
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  933
  

⊟Protein

⊟General

• locus tag: EGJ38_RS10795 [old locus tag: EGJ38_002163 ]
• symbol: LacC
• description: tagatose-6-phosphate kinase
• length: 310
• theoretical pI: 4.66537
• theoretical MW: 33833.2
• GRAVY: -0.0945161

⊟Function

• reaction:
  EC 2.7.1.144?  ExPASy
  Tagatose-6-phosphate kinase ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate
• TIGRFAM:
  Metabolism Energy metabolism Biosynthesis and degradation of polysaccharides tagatose-6-phosphate kinase (TIGR01231; EC 2.7.1.144; HMM-score: 616.4)
  and 6 more
  hexose kinase, 1-phosphofructokinase family (TIGR03168; EC 2.7.1.-; HMM-score: 324.9)
  1-phosphofructokinase (TIGR03828; EC 2.7.1.56; HMM-score: 280.4)
  Metabolism Energy metabolism Sugars ribokinase (TIGR02152; EC 2.7.1.15; HMM-score: 64.6)
  Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides bifunctional protein RfaE, domain I (TIGR02198; EC 2.7.1.-; HMM-score: 61)
  Metabolism Energy metabolism Sugars 5-dehydro-2-deoxygluconokinase (TIGR04382; EC 2.7.1.92; HMM-score: 48.6)
  Unknown function General YjeF family C-terminal domain (TIGR00196; HMM-score: 43)
• TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
• PFAM:
  Ribokinase (CL0118) PfkB; pfkB family carbohydrate kinase (PF00294; HMM-score: 226.6)
  and 4 more
  Carb_kinase; NAD(P)H-hydrate dehydratase (PF01256; HMM-score: 42.1)
  Phos_pyr_kin; Phosphomethylpyrimidine kinase (PF08543; HMM-score: 19.9)
  NADP_Rossmann (CL0063) ADH_zinc_N; Zinc-binding dehydrogenase (PF00107; HMM-score: 12.2)
  no clan defined DUF7360; Domain of unknown function (DUF7360) (PF24059; HMM-score: 11.3)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• DeepLocPro: Cytoplasmic
  • Cytoplasmic Score: 0.9974
  • Cytoplasmic Membrane Score: 0.0003
  • Cell wall & surface Score: 0.0004
  • Extracellular Score: 0.0018
• LocateP:
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.013235
  • TAT(Tat/SPI): 0.000863
  • LIPO(Sec/SPII): 0.000994
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI:
• RefSeq: WP_000604138 NCBI
• UniProt:

⊟Additional information (user-provided)

⊟Protein sequence

• MILTLTLNPSVDISYPLTALKLDDVNRVQEVSKTAGGKGLNVTRVLAQVGEPVLASGFIGGELGQFIAKKLDHADIKHAFYNIKGETRNCIAILHEGQQTEILEQGPEIDNQEAAGFIKHFEQLLEKVEAVAISGSLPKGLNQDYYAQIIERCQNKGVPVILDCSGATLQTVLENPYKPTVIKPNISELYQLLNQPLDESLESLKQAVSQPLFEGIEWIIVSLGAQGALAKHNHTFYRVNIPTISVLNPVGSGDSTVAGITSAILNHENDHDLLKKANTLGMLNAQEAQTGYVNLNNYDELFNQIEVLEV

⊟Experimental data

• experimentally validated:
• protein localization:
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator: LacR see EGJ38_002163

⊟Additional information (user-provided)

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Additional information (user-provided)

⊟Other information (user-provided)

You can add further information about the gene and protein here. [edit]

⊟Literature

⊟References

⊟Relevant publications