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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS05750 [old locus tag: SACOL1126 ]
  • pan locus tag?: SAUPAN003344000
  • symbol: SACOL_RS05750
  • pan gene symbol?: ctaM
  • synonym:
  • product: membrane protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SACOL_RS05750 [old locus tag: SACOL1126 ]
  • symbol: SACOL_RS05750
  • product: membrane protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1138352..1138813
  • length: 462
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Location: NC_002951 (1138352..1138813) NCBI
  • BioCyc: SACOL_RS05750 BioCyc
  • MicrobesOnline: see SACOL1126

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGGGCGTTCCAATTTTACCAACGATTAGTACGACATGTATTGTCATTAGTGCAATTTTA
    ATTGCCATTGGTTGGAGACTTATTTGGAAAAGGGAAATAAATAAACACAAAAATGTTATG
    TTAGCTGCAGCTGTTTTTGCTTTAACTTTTTTCTTAATCTATGCAAGTAGAACGATTTTT
    ATCGGTAATACAGCATTTGGCGGACCAGCATCAATTAAGAAATATTATACGATTTTCTTA
    TTTTTCCACATTAATTTAGCAACAATTGGTGGTATTCTAGGCCTAGTTCAAATTATTACT
    GCATTTAAAGATAAATATAATGTACACCGCAAATTCGGGCCATTCGCTTCAGTTATATGG
    TTCTGTACTGCAATTACAGGTGTAGCAGTTTACTTATTATTATATGTATTATATCCAGGT
    GGAGAAACGACATCACTGATTAAAGCAACATTTGGTCATTAA
    60
    120
    180
    240
    300
    360
    420
    462

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SACOL_RS05750 [old locus tag: SACOL1126 ]
  • symbol: SACOL_RS05750
  • description: membrane protein
  • length: 153
  • theoretical pI: 10.3728
  • theoretical MW: 16909.2
  • GRAVY: 0.870588

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: see SACOL1126
  • PFAM:
    no clan defined DUF420; Protein of unknown function (DUF420) (PF04238; HMM-score: 126.5)
    and 7 more
    DUF2306; Predicted membrane protein (DUF2306) (PF10067; HMM-score: 34.8)
    DUF3488; Domain of unknown function (DUF3488) (PF11992; HMM-score: 13.7)
    DUF4750; Domain of unknown function (DUF4750) (PF15938; HMM-score: 11.7)
    TMCCDC2; Transmembrane and coiled-coil domain-containing protein 2 (PF15844; HMM-score: 11.5)
    Tetraspannin (CL0347) Tetraspannin; Tetraspanin family (PF00335; HMM-score: 9.4)
    no clan defined DHHC; DHHC palmitoyltransferase (PF01529; HMM-score: 9.4)
    DUF4131; Domain of unknown function (DUF4131) (PF13567; HMM-score: 7)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 4
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002487
    • TAT(Tat/SPI): 0.000157
    • LIPO(Sec/SPII): 0.004627
  • predicted transmembrane helices (TMHMM): 4

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MGVPILPTISTTCIVISAILIAIGWRLIWKREINKHKNVMLAAAVFALTFFLIYASRTIFIGNTAFGGPASIKKYYTIFLFFHINLATIGGILGLVQIITAFKDKYNVHRKFGPFASVIWFCTAITGVAVYLLLYVLYPGGETTSLIKATFGH

Experimental data[edit | edit source]

  • experimentally validated: see SACOL1126
  • protein localization: see SACOL1126
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]