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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS03815 [old locus tag: SACOL0743 ]
  • pan locus tag?: SAUPAN002567000
  • symbol: SACOL_RS03815
  • pan gene symbol?: uppP
  • synonym:
  • product: undecaprenyl-diphosphatase

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SACOL_RS03815 [old locus tag: SACOL0743 ]
  • symbol: SACOL_RS03815
  • product: undecaprenyl-diphosphatase
  • replicon: chromosome
  • strand: -
  • coordinates: 763347..764222
  • length: 876
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Location: NC_002951 (763347..764222) NCBI
  • BioCyc: SACOL_RS03815 BioCyc
  • MicrobesOnline: see SACOL0743

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGTTTATCATTGAATTAATAAAAGGTATTATCTTAGGGGTCGTCGAAGGATTAACAGAA
    TTTGCACCTGTTTCCTCTACTGGACATATGATCCTAGTTGATGATATGTGGTTAAAATCA
    TCTGAATTTTTAGGTTCTCAGTCAGCATTTACATTTAAAATCGTCATCCAATTAGGATCC
    GTCTTTGCAGCAGCATGGGTGTTCCGCGAACGCTTCTTAGAGATTTTACATATTGGTAAA
    CACAAACATGTTGAAGGAGATAACGATCAACAAAGACGTTCAAAGCCAAGACGTTTAAAT
    TTATTACATGTATTAGTGGGTATGGTGCCAGCAGGTATTTTAGGCTTACTATTTGATGAT
    TTCATCGAAGAACATTTATTTAGTGTGCCAACTGTTATGATTGGCTTATTCGTAGGTGCT
    ATCTATATGATTATTGCTGATAAATACTCAGCTAAAGTTAAAAACCCACAAACAGTAGAT
    CAAATCAGTTATTTCCAAGCATTTGTAATTGGTATTTCTCAAGCAGTAGCTATGTGGCCT
    GGTTTCAGCCGTTCAGGCTCAACAATTTCAACTGGGGTATTAATGAAATTAAATCATAAA
    GCAGCATCGGACTTTACATTTATTATGGCTGTTCCAATTATGTTAGCAGCTAGTGGTTTA
    TCTTTATTAAAACATTATCAAGATATTCAGATTGCTGATATACCTTTTTATATTTTAGGC
    TTTTTAGCTGCATTTACTGTTGGACTAATTGCAATCAAAACATTCTTGCATCAAATTAAC
    AAAATCAAACTAATTCCATTTGCCATTTACAGAATTGTATTAGTAATCTTTATTGCTATA
    CTTTACTTCGGATTTGGCATTGGTAAAGGTATTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    876

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SACOL_RS03815 [old locus tag: SACOL0743 ]
  • symbol: SACOL_RS03815
  • description: undecaprenyl-diphosphatase
  • length: 291
  • theoretical pI: 9.6824
  • theoretical MW: 32284.2
  • GRAVY: 0.703093

Function[edit | edit source]

  • reaction:
    EC 3.6.1.27?  ExPASy
    Undecaprenyl-diphosphate phosphatase Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate
  • TIGRFAM:
    Cell structure Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan undecaprenyl-diphosphatase UppP (TIGR00753; EC 3.6.1.27; HMM-score: 277)
    and 1 more
    Genetic information processing Mobile and extrachromosomal element functions Prophage functions holin, BlyA family (TIGR01606; HMM-score: 11)
  • TheSEED: see SACOL0743
  • PFAM:
    LysE (CL0292) BacA; Bacitracin resistance protein BacA (PF02673; HMM-score: 262.6)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 6
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.011413
    • TAT(Tat/SPI): 0.000345
    • LIPO(Sec/SPII): 0.003051
  • predicted transmembrane helices (TMHMM): 8

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MFIIELIKGIILGVVEGLTEFAPVSSTGHMILVDDMWLKSSEFLGSQSAFTFKIVIQLGSVFAAAWVFRERFLEILHIGKHKHVEGDNDQQRRSKPRRLNLLHVLVGMVPAGILGLLFDDFIEEHLFSVPTVMIGLFVGAIYMIIADKYSAKVKNPQTVDQISYFQAFVIGISQAVAMWPGFSRSGSTISTGVLMKLNHKAASDFTFIMAVPIMLAASGLSLLKHYQDIQIADIPFYILGFLAAFTVGLIAIKTFLHQINKIKLIPFAIYRIVLVIFIAILYFGFGIGKGI

Experimental data[edit | edit source]

  • experimentally validated: see SACOL0743
  • protein localization: see SACOL0743
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]