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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS10545 [old locus tag: SA1838 ]
  • pan locus tag?: SAUPAN005267000
  • symbol: SA_RS10545
  • pan gene symbol?: mroQ
  • synonym:
  • product: CPBP family intramembrane metalloprotease

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS10545 [old locus tag: SA1838 ]
  • symbol: SA_RS10545
  • product: CPBP family intramembrane metalloprotease
  • replicon: chromosome
  • strand: +
  • coordinates: 2074492..2075235
  • length: 744
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002745 (2074492..2075235) NCBI
  • BioCyc: SA_RS10545 BioCyc
  • MicrobesOnline: see SA1838

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGACAAGATTATGGGCATCATTGCTAACTGTTATTATTTATATATTGTCTCAATTTTTA
    CCGCTTCTCATTGTAAAAAAATTACCATTTGTACAATATAGTGGCATAGAACTGACTAAA
    GCAGTCATTTACATACAACTTGTTCTATTTTTAATCGCCGCCACGACGATTATTTTAATT
    AATTTAAAAATTAAAAATCCAACAAAATTAGAATTAGAAGTTAAAGAACCTAAAAAATAT
    ATCATTCCATGGGCATTGCTTGGATTTGCATTGGTAATGATTTATCAAATGGTAGTGAGC
    ATTGTATTAACGCAAATTTATGGTGGACAACAAGTAAGTCCTAATACAGAAAAGCTAATT
    ATTATTGCTCGAAAAATACCTATATTTATCTTCTTTGTATCTATTATCGGTCCTTTATTA
    GAAGAATACGTATTCAGAAAAGTAATCTTTGGAGAATTATTTAATGCGATTAAAGGTAAT
    CGTATCGTAGCATTTATTATTGCTACAACAGTAAGTTCATTAATATTTGCATTAGCACAT
    AATGATTTCAAATTTATTCCAGTTTATTTTGGTATGGGCGTCATTTTTTCATTAGCATAT
    GTATGGACAAAACGGCTTGCTGTTCCAATTATTATCCATATGTTACAAAACGGATTTGTC
    GTTATATTCCAATTACTTAATCCTGAAGCTTTGAAAAAAGCCACGGAACAAGCGAATTTT
    ATATATCACATTTTTATTCCATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    744

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA_RS10545 [old locus tag: SA1838 ]
  • symbol: SA_RS10545
  • description: CPBP family intramembrane metalloprotease
  • length: 247
  • theoretical pI: 10.2821
  • theoretical MW: 28163.1
  • GRAVY: 0.940081

⊟Function[edit | edit source]

  • ⊞TIGRFAM:
    exosortase E/protease, VPEID-CTERM system (TIGR04162; EC 3.4.22.-; HMM-score: 28.4)
    and 1 more
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides CAAX prenyl protease-related protein (TIGR03008; HMM-score: 22.4)
  • TheSEED: see SA1838
  • ⊞PFAM:
    Peptidase_U (CL0472) Rce1-like; Type II CAAX prenyl endopeptidase Rce1-like (PF02517; HMM-score: 67.4)
    and 1 more
    no clan defined DUF5698; Domain of unknown function (DUF5698) (PF18955; HMM-score: 17.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 6
  • ⊞DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.9983
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0016
  • LocateP:
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.007879
    • TAT(Tat/SPI): 0.000185
    • LIPO(Sec/SPII): 0.023779
  • predicted transmembrane helices (TMHMM): 6

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MTRLWASLLTVIIYILSQFLPLLIVKKLPFVQYSGIELTKAVIYIQLVLFLIAATTIILINLKIKNPTKLELEVKEPKKYIIPWALLGFALVMIYQMVVSIVLTQIYGGQQVSPNTEKLIIIARKIPIFIFFVSIIGPLLEEYVFRKVIFGELFNAIKGNRIVAFIIATTVSSLIFALAHNDFKFIPVYFGMGVIFSLAYVWTKRLAVPIIIHMLQNGFVVIFQLLNPEALKKATEQANFIYHIFIP

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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