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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS06735 [old locus tag: SA1185 ]
  • pan locus tag?: SAUPAN003738000
  • symbol: SA_RS06735
  • pan gene symbol?: —
  • synonym:
  • product: 4-hydroxybenzoyl-CoA thioesterase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS06735 [old locus tag: SA1185 ]
  • symbol: SA_RS06735
  • product: 4-hydroxybenzoyl-CoA thioesterase
  • replicon: chromosome
  • strand: +
  • coordinates: 1352174..1352641
  • length: 468
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002745 (1352174..1352641) NCBI
  • BioCyc: SA_RS06735 BioCyc
  • MicrobesOnline: see SA1185

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGATATATAGTATTACAGAAATAGAAGCGCGTTATGCTGAAACTGATAAGATGGGTGTA
    ATTTATCACGGGAATTATGCAACTTGGTTTGAAGTTGCGCGGTTGGATTATATATCGAAG
    TTAGGTTTTAGTTATGCTGATATGGAAAAACAAGGAATCATTTCACCTGTGACTGACCTC
    AATGTCAATTATAAAAAGTCTATTTTTTATCCAGAAAAAGTTAAAGTTAAAACTTGGGTT
    GAAAAATATTCGAGATTACGTTCAGTGTATAAATATGAGATTTTTAATGAAAAAGGTGAA
    CTTGCAACTACAGGTTCCACAGAATTGATTTGCATTAAAGAAGATACTTTTAAGCCTATA
    CGGTTGGATCGTTATTTCCCAGATTGGCATGAAGCTTATAGTAAAGTGCAAACGCTCAAT
    AATGAAGGGAAAACAGTAGAGATAATGGATGGTATTGATTCTTTATAA
    60
    120
    180
    240
    300
    360
    420
    468

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA_RS06735 [old locus tag: SA1185 ]
  • symbol: SA_RS06735
  • description: 4-hydroxybenzoyl-CoA thioesterase
  • length: 155
  • theoretical pI: 5.34661
  • theoretical MW: 18175.6
  • GRAVY: -0.452258

⊟Function[edit | edit source]

  • ⊞TIGRFAM:
    Unknown function General acyl-CoA thioester hydrolase, YbgC/YbaW family (TIGR00051; HMM-score: 101.2)
    and 3 more
    tol-pal system-associated acyl-CoA thioesterase (TIGR02799; EC 3.1.2.-; HMM-score: 61.1)
    uncharacterized domain 1 (TIGR00369; HMM-score: 15.8)
    superoxide dismutase, Ni (TIGR02753; EC 1.15.1.1; HMM-score: 12.9)
  • TheSEED: see SA1185
  • ⊞PFAM:
    HotDog (CL0050) 4HBT; Thioesterase superfamily (PF03061; HMM-score: 66)
    and 3 more
    4HBT_2; Thioesterase-like superfamily (PF13279; HMM-score: 52.5)
    Acyl-ACP_TE; Acyl-ACP thioesterase N-terminal domain (PF01643; HMM-score: 31.6)
    no clan defined NOMO_8th; NOMO eighth prealbumin-like domain (PF23660; HMM-score: 13.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • ⊞DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.874
    • Cytoplasmic Membrane Score: 0.0566
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0694
  • LocateP:
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.00707
    • TAT(Tat/SPI): 0.000322
    • LIPO(Sec/SPII): 0.000785
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MIYSITEIEARYAETDKMGVIYHGNYATWFEVARLDYISKLGFSYADMEKQGIISPVTDLNVNYKKSIFYPEKVKVKTWVEKYSRLRSVYKYEIFNEKGELATTGSTELICIKEDTFKPIRLDRYFPDWHEAYSKVQTLNNEGKTVEIMDGIDSL

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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