⊟Summary[edit | edit source]

PangenomeCOLN315NCTC8325NewmanUSA300_FPR3757JSNZ04-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

⊟Summary

• organism: Staphylococcus aureus N315
locus tag: SA_RS05165 [old locus tag: SA0911 ]
pan locus tag^?: SAUPAN003268000
symbol: SA_RS05165
pan gene symbol^?: qoxC
• synonym:
• product: quinol oxidase subunit 3

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SA_RS05165 [old locus tag: SA0911 ]
• symbol: SA_RS05165
• product: quinol oxidase subunit 3
• replicon: chromosome
• strand: -
• coordinates: 1035108..1035713
• length: 606
• essential: no DEG other strains

⊟Accession numbers

• Location: NC_002745 (1035108..1035713) NCBI
• BioCyc: SA_RS05165 BioCyc
• MicrobesOnline: see SA0911

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
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  481
  541
  601
  
  ATGAGTCATGATACAAACACTATTGATTCACGCACACATGAAGGCGAATTAAATAAGCTT
  GGCTTTTGGATTTTCATTACAGCCGAATTTGCGTTATTCGGTACCCTATTTGCGACACTA
  TTAACTTTGCAACATGGTGGCGATTATGCAGGTAAAATGACTACTGAGTTATTTGAATTG
  CCTCTTGTTTTAATAATGACGTTTGCATTATTATTCAGTTCTTACACATGTGGTATTGCT
  ATTTACTACATGCGCCAAGAAAAACAAAAGTTAATGATGTTTTGGATGATCATTACGTTA
  CTTTTAGGTTTAGTCTTTGTTGGATTCGAAATTTATGAATTCGCACACTATGCATCAGAA
  GGCGTTAACCCAACAATTGGTTCTTACTGGTCTAGTTTCTTTATCCTATTAGGAACGCAT
  GGTTGTCACGTATCGCTAGGTATCGTTTGGGCCATTTGTTTATTAATCCAAATCCAACGA
  CGCGGATTAGACAAATATAATGCGCCAAAATTATTTATAGTAAGTTTATACTGGCACTTC
  TTAGATGTTGTTTGGGTTTTCATCTTTACTGCCGTATATATGATAGGGATGGTGTATAGC
  GGATGA
  60
  120
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  300
  360
  420
  480
  540
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  606
  

⊟Protein

⊟General

• locus tag: SA_RS05165 [old locus tag: SA0911 ]
• symbol: SA_RS05165
• description: quinol oxidase subunit 3
• length: 201
• theoretical pI: 6.38351
• theoretical MW: 23057
• GRAVY: 0.666169

⊟Function

• ⊞⊞reaction:
  EC 1.10.3.-?  ExPASy
  2 a quinol + O₂ = 2 a quinone + 2 H₂O?
• ⊞⊞TIGRFAM:
  Metabolism Energy metabolism Electron transport cytochrome aa3 quinol oxidase, subunit III (TIGR02897; EC 1.10.3.-; HMM-score: 359)
  and 1 more
  Metabolism Energy metabolism Electron transport cytochrome o ubiquinol oxidase, subunit III (TIGR02842; EC 1.10.3.-; HMM-score: 188.3)
• TheSEED: see SA0911
• ⊞⊞PFAM:
  no clan defined COX3; Cytochrome c oxidase subunit III (PF00510; HMM-score: 51.6)
  and 2 more
  STE2; Fungal pheromone mating factor STE2 GPCR (PF02116; HMM-score: 18.6)
  PsbL; PsbL protein (PF02419; HMM-score: 13.7)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• ⊞⊞PSORTb: Cytoplasmic Membrane
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 10
  • Cellwall Score: 0
  • Extracellular Score: 0
  • Internal Helices: 5
• ⊞⊞DeepLocPro: Cytoplasmic Membrane
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 0.9996
  • Cell wall & surface Score: 0
  • Extracellular Score: 0.0004
• LocateP:
• ⊞⊞SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.005078
  • TAT(Tat/SPI): 0.000723
  • LIPO(Sec/SPII): 0.001671
• predicted transmembrane helices (TMHMM): 5

⊟Accession numbers

• GI: 445939881 NCBI
• RefSeq: WP_000017736 NCBI
• UniProt: see SA0911

⊟Protein sequence

• MSHDTNTIDSRTHEGELNKLGFWIFITAEFALFGTLFATLLTLQHGGDYAGKMTTELFELPLVLIMTFALLFSSYTCGIAIYYMRQEKQKLMMFWMIITLLLGLVFVGFEIYEFAHYASEGVNPTIGSYWSSFFILLGTHGCHVSLGIVWAICLLIQIQRRGLDKYNAPKLFIVSLYWHFLDVVWVFIFTAVYMIGMVYSG

⊟Experimental data

• experimentally validated: data available for COL, NCTC8325
• protein localization: data available for COL
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊞Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊞Other Information

You can add further information about the gene and protein here. [edit]

⊟Literature

⊟References

⊟Relevant publications