PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159JSNZLGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

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⊟Summary

• organism: Staphylococcus aureus COL
locus tag: SACOL_RS04660 [old locus tag: SACOL0908 ]
pan locus tag^?: SAUPAN002880000
symbol: SACOL_RS04660
pan gene symbol^?: ear
• synonym:
• product: hypothetical protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SACOL_RS04660 [old locus tag: SACOL0908 ]
• symbol: SACOL_RS04660
• product: hypothetical protein
• replicon: chromosome
• strand: -
• coordinates: 917356..917913
• length: 558
• essential: unknown

⊟Accession numbers

• Location: NC_002951 (917356..917913) NCBI
• BioCyc: SACOL_RS04660 BioCyc
• MicrobesOnline: see SACOL0908

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
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  ATGAATAAAAAACTATTAACAAGAACATTGATAGCAAGTGCTTTAGTTTTAACAACAGTA
  GGTTCAGGTTTTCATTCTTCTTCAAATTATAATGGTATTAATAACGTTGCAAAGGCTTCT
  GAAATAACAGATAGAGACTTATGGAAAAATGTAAGAGATGCTTTGAAAGAAGCAAATATT
  ATCGATAAAACAGCAAATGAGACAGTTGGTGTTACGTACAATTTAAATAATGGTGGCGAA
  AGTAGTATTACGGGTACAGCTGATTTAGATGAACTTAGTAATTTTAATAACAAGCCGATT
  AATACCGATAGTGTTAAAAGAATTGATTTGTCAAGAATAAATCCAAATGGAAATAGGTTT
  GACGCAAATGATGCATGGAAAAAATTAACTGACAAATTAAAAGAGAAACAAATCGTTAAA
  AACGGCGACACAGTAACTATCCATAGTAAAGATAAAAATGATCCCCCAATTTCAGCTAAA
  GTTGGTGAAAACTATAATGGCAACAAGGGGTTAATGCTAAATCAGAGAGATATAACAAAA
  ATAACTATAACTAAATAA
  60
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  558
  

⊟Protein

⊟General

• locus tag: SACOL_RS04660 [old locus tag: SACOL0908 ]
• symbol: SACOL_RS04660
• description: hypothetical protein
• length: 185
• theoretical pI: 9.99344
• theoretical MW: 20345.7
• GRAVY: -0.692432

⊟Function

• TIGRFAM:
  Genetic information processing Mobile and extrachromosomal element functions Prophage functions putative phage terminase, small subunit, P27 family (TIGR01558; HMM-score: 17.9)
• TheSEED: see SACOL0908
• ⊞PFAM:
  no clan defined DUF4888; Domain of unknown function (DUF4888) (PF16229; HMM-score: 75.7)
  and 1 more
  DUF7599; Domain of unknown function (DUF7599) (PF24538; HMM-score: 19.2)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• ⊞PSORTb: unknown (no significant prediction)
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 3.33
  • Cellwall Score: 3.33
  • Extracellular Score: 3.33
  • Internal Helices: 0
• ⊞DeepLocPro: Extracellular
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 0.0001
  • Cell wall & surface Score: 0.0166
  • Extracellular Score: 0.9833
• LocateP:
• ⊞SignalP: Signal peptide SP(Sec/SPI) length 39 aa
  • SP(Sec/SPI): 0.757326
  • TAT(Tat/SPI): 0.010019
  • LIPO(Sec/SPII): 0.181312
  • Cleavage Site: CS pos: 39-40. AKA-SE. Pr: 0.4390
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 446958375 NCBI
• RefSeq: WP_001035631 NCBI
• UniProt: see SACOL0908

⊟Protein sequence

• MNKKLLTRTLIASALVLTTVGSGFHSSSNYNGINNVAKASEITDRDLWKNVRDALKEANIIDKTANETVGVTYNLNNGGESSITGTADLDELSNFNNKPINTDSVKRIDLSRINPNGNRFDANDAWKKLTDKLKEKQIVKNGDTVTIHSKDKNDPPISAKVGENYNGNKGLMLNQRDITKITITK

⊟Experimental data

• experimentally validated: see SACOL0908
• protein localization: see SACOL0908
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator: SaeR see SACOL0908

⊟Transcription pattern

• S.aureus Expression Data Browser: no data available

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊞Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊞Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications