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NCBI: 06-JUL-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_2076 [new locus tag: NWMN_RS12025 ]
  • pan locus tag?: SAUPAN005565000
  • symbol: NWMN_2076
  • pan gene symbol?: htsC
  • synonym: fecD
  • product: FecCD iron compound ABC transporter permease family protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_2076 [new locus tag: NWMN_RS12025 ]
  • symbol: NWMN_2076
  • product: FecCD iron compound ABC transporter permease family protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2312237..2313205
  • length: 969
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGATGACAACGAAAATTATACGTCGTTATAGTTTAATCACAATCCTTTTAATTGTGAGT
    ATATTCATAAGTTTATGTGTAGGGTCTGTCATGATTCATCCGATTGATGCTATTAAGGGA
    ATCTTTACACAAGATGATTTTATTTTAAATGAGTATCGTATACCTAGAACATTACTTGGT
    ATTATTATCGGTAGTAGCTTGGCTATTTCAGGTGCAATTATACAAGCTGTAATAAGAAAC
    CCGTTAGCCTCACCTGATGTTATAGGTATTTCTAAAGGTGCCAGTTTAGCTGCTGTGATT
    ATTATTATGACCTTTCCAACAGCACCATTGTTTGTATTACCTATAGGTTCATTCTTAGGT
    GCCTTTGCAGTAAGTTTATTTTTATCATTTTTAATTTCAAAATATGATGTTAAAGGTTCA
    AAGCTTGCCTTAATTGGTTTAGCAATAGGCGCAATATGTACGGCGATTGTGCAGTTCTTA
    TTAATCAGAAATCCACTGGAAGCAAACAAAGCGCTTGTTTGGTTGACAGGTAGTCTATAT
    GGACATGATATGTCGAATATTTATACTATATTACCTTGGTTTTTAATAACGATACCAATC
    ATCATTTTATTGAGTTATCAATTAGATGTATTGAATCTAGGTGATGCTGTTGCAACCGCA
    CTCGGTTTAAAAGTTAAAACTATTAAAATGCTATTGTTAATTTTAGCAGTAATATTAGCA
    GGATCCGCAATTTCAGTTGTCGGTGGTATTAGCTTTTTAGGATTAATTGCACCTCATATT
    GCGAGACAATTAATAGGAAATAAAACATTACACGTTATTATCATGTCGGGGTTAATTGGT
    GCTATATTGTTAACATTTGGAGATGGTTTAGCCCGTGGCATTCATCCGCCACTGGATATT
    CCTGTTGGGGTTATCATTGCAATTATCGGTGCACCATACTTCTTAATATTATTACGAAGA
    ATGAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    969

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: NWMN_2076 [new locus tag: NWMN_RS12025 ]
  • symbol: NWMN_2076
  • description: FecCD iron compound ABC transporter permease family protein
  • length: 322
  • theoretical pI: 10.2795
  • theoretical MW: 34347.7
  • GRAVY: 1.19379

⊟Function[edit | edit source]

  • TIGRFAM:
    proposed F420-0 ABC transporter, permease protein (TIGR03869; HMM-score: 172.1)
  • TheSEED  :
    • Heme ABC type transporter HtsABC, permease protein HtsC
    Iron acquisition and metabolism Iron acquisition and metabolism - no subcategory Heme, hemin uptake and utilization systems in GramPositives  Heme ABC type transporter HtsABC, permease protein HtsC
  • ⊞PFAM:
    Membrane_trans (CL0142) FecCD; FecCD transport family (PF01032; HMM-score: 307.5)
    and 1 more
    ABC-3; ABC 3 transport family (PF00950; HMM-score: 24.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 8
  • ⊞DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.9999
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0001
  • ⊞LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: -0.5
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.115119
    • TAT(Tat/SPI): 0.001049
    • LIPO(Sec/SPII): 0.320841
  • predicted transmembrane helices (TMHMM): 8

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MMTTKIIRRYSLITILLIVSIFISLCVGSVMIHPIDAIKGIFTQDDFILNEYRIPRTLLGIIIGSSLAISGAIIQAVIRNPLASPDVIGISKGASLAAVIIIMTFPTAPLFVLPIGSFLGAFAVSLFLSFLISKYDVKGSKLALIGLAIGAICTAIVQFLLIRNPLEANKALVWLTGSLYGHDMSNIYTILPWFLITIPIIILLSYQLDVLNLGDAVATALGLKVKTIKMLLLILAVILAGSAISVVGGISFLGLIAPHIARQLIGNKTLHVIIMSGLIGAILLTFGDGLARGIHPPLDIPVGVIIAIIGAPYFLILLRRMK

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • ⊞regulator: Fur* (repression) regulon

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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